Literature DB >> 21066926

Arthroprosthetic cobaltism: identification of the at-risk patient.

Stephen Tower1.   

Abstract

MoM hip bearings are being scrutinized due to high early failure rates and concerns that the results of the revision surgeries will be poor. However, orthopedic surgeons and the general medical community are unaware that patients with MoM bearings are also at risk for cobaltism. Medical providers need to know that hip arthroplasty implantees that present with symptom complexes that include tinnitus, deafness, vertigo, visual changes, rashes, hypothyroidism, tremor, dyspnea on exertion, mood disorders, dementia, heart failure, and peripheral neuropathy may be presenting arthroprosthetic cobaltism. These patients need to be asked if they have had a hip replacement and if so what type. For those patients implanted with a MoM bearing or those with a history of hip revision for a failed ceramic bearing obtaining a [Co] is indicated. MoM implantees with renal failure are a particularly high risk for cobaltism. A [Co] can be measured by many reference laboratories from royal blue top trace elements tube of venous blood. Venipuncture with a standard needle is adequate as long as a red stoppered tube is drawn first. The radiographic appearance of a MoM bearing is readily apparent to an orthopedic surgeon. The patient's operative report will usually specify the bearing type. Given that the publicity of the recent ASR bearing recall medical providers will be contacted by worried patients concerned about their hip implants. Most patients with hip replacements will not know the brand or material of their bearings. Providing patients with copies of their hip implant inventory might avoid worry by the majority of patients with hip arthroplasties that are not at risk. Patients with a cobalt levels of greater than 7 mcg/l bear observation of neurologic and cardiac function. Those patients with levels greater than 20 should be advised to have revision of their hip arthroplasty to a bearing that eliminates cobalt. Most patients implanted with MoM bearing have cobalt levels greater than those allowed in industry and cobalt exposed workers may have an increased incidence of subclinical cognitive and cardiac impairments. This association merits further study. Table 1 is a summation of the previously referenced data of this paper that might assist the clinician in interpreting a [Co].

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Year:  2010        PMID: 21066926

Source DB:  PubMed          Journal:  Alaska Med        ISSN: 0002-4538


  11 in total

1.  Revision for taper corrosion at the head-neck junction: pearls and pitfalls.

Authors:  Brian J McGrory; Brigham R McKenney
Journal:  Curr Rev Musculoskelet Med       Date:  2016-03

2.  Cobalt and Chromium Ion Release in Metal-on-Polyethylene and Ceramic-on-Polyethylene THA: A Simulator Study With Cellular and Microbiological Correlations.

Authors:  Cody C Wyles; Christopher R Paradise; Thao L Masters; Robin Patel; Andre J van Wijnen; Matthew P Abdel; Robert T Trousdale; Rafael J Sierra
Journal:  J Arthroplasty       Date:  2019-11-27       Impact factor: 4.757

3.  Self-reported systemic complaints in patients with metal-on-metal hip arthroplasty.

Authors:  Jetse Jelsma; Martijn Schotanus; Henne Kleinveld; Bernd Grimm; Ide Heyligers
Journal:  J Orthop       Date:  2020-01-25

4.  Cobalt-chromium toxic retinopathy case study.

Authors:  Warren Apel; Denis Stark; Anthony Stark; Stephen O'Hagan; Joseph Ling
Journal:  Doc Ophthalmol       Date:  2012-12-15       Impact factor: 2.379

5.  [Metal ion concentrations in patients with metal-metal bearings in prostheses].

Authors:  J P Kretzer; C Van Der Straeten; R Sonntag; U Müller; M Streit; B Moradi; S Jäger; J Reinders
Journal:  Orthopade       Date:  2013-08       Impact factor: 1.087

6.  Ultrasound-based decision making following metal-on-metal hip arthroplasty.

Authors:  Remo Goderecci; Andrea Fidanza; Stefano Necozione; Vincenzo Francione; Pier Francesco Indelli; Vittorio Calvisi
Journal:  J Clin Orthop Trauma       Date:  2019-04-16

7.  Arthroprosthetic cobaltism associated with cardiomyopathy.

Authors:  Ryan S Charette; Alexander L Neuwirth; Charles L Nelson
Journal:  Arthroplast Today       Date:  2016-12-15

Review 8.  A Review of Mitochondrial Optic Neuropathies: From Inherited to Acquired Forms.

Authors:  Yasmine L Pilz; Sherry J Bass; Jerome Sherman
Journal:  J Optom       Date:  2016-12-28

9.  A Systematic Review of Systemic Cobaltism After Wear or Corrosion of Chrome-Cobalt Hip Implants.

Authors:  Bradford D Gessner; Thomas Steck; Erik Woelber; Stephen S Tower
Journal:  J Patient Saf       Date:  2019-06       Impact factor: 2.844

10.  N-Acetyl-Cysteine as Effective and Safe Chelating Agent in Metal-on-Metal Hip-Implanted Patients: Two Cases.

Authors:  Andrea Giampreti; Davide Lonati; Benedetta Ragghianti; Anna Ronchi; Valeria Margherita Petrolini; Sarah Vecchio; Carlo Alessandro Locatelli
Journal:  Case Rep Orthop       Date:  2016-04-11
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