Literature DB >> 21063425

Genome mining and biosynthesis of fumitremorgin-type alkaloids in ascomycetes.

Shu-Ming Li1.   

Abstract

This review summarizes the recent progress on the biosynthesis of fumitremorgin-type alkaloids; that is, the identification of the biosynthetic gene clusters from genome sequences by genome mining and proof of gene function by molecular biological and biochemical investigations.

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Year:  2010        PMID： 21063425     DOI： 10.1038/ja.2010.128

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  9 in total

1.  Prototype of an intertwined secondary-metabolite supercluster.

Authors:  Philipp Wiemann; Chun-Jun Guo; Jonathan M Palmer; Relebohile Sekonyela; Clay C C Wang; Nancy P Keller
Journal:  Proc Natl Acad Sci U S A       Date:  2013-09-30       Impact factor: 11.205

2.  Distinct mechanisms for spiro-carbon formation reveal biosynthetic pathway crosstalk.

Authors:  Yuta Tsunematsu; Noriyasu Ishikawa; Daigo Wakana; Yukihiro Goda; Hiroshi Noguchi; Hisao Moriya; Kinya Hotta; Kenji Watanabe
Journal:  Nat Chem Biol       Date:  2013-10-13       Impact factor: 15.040

3.  Biochemical characterization of NotB as an FAD-dependent oxidase in the biosynthesis of notoamide indole alkaloids.

Authors:  Shengying Li; Jennifer M Finefield; James D Sunderhaus; Timothy J McAfoos; Robert M Williams; David H Sherman
Journal:  J Am Chem Soc       Date:  2011-12-28       Impact factor: 15.419

4.  Comparative analysis of the biosynthetic systems for fungal bicyclo[2.2.2]diazaoctane indole alkaloids: the (+)/(-)-notoamide, paraherquamide and malbrancheamide pathways.

Authors:  Shengying Li; Krithika Anand; Hong Tran; Fengan Yu; Jennifer M Finefield; James D Sunderhaus; Timothy J McAfoos; Sachiko Tsukamoto; Robert M Williams; David H Sherman
Journal:  Medchemcomm       Date:  2012-08       Impact factor: 3.597

5.  Engineered Production of Tryprostatins in E. coli through Reconstitution of a Partial ftm Biosynthetic Gene Cluster from Aspergillus sp.

Authors:  Gopitkumar R Shah; Shane R Wesener; Yi-Qiang Cheng
Journal:  Jacobs J Biotechnol Bioeng       Date:  2014-12-18

6.  Aspergillus hancockii sp. nov., a biosynthetically talented fungus endemic to southeastern Australian soils.

Authors:  John I Pitt; Lene Lange; Alastair E Lacey; Daniel Vuong; David J Midgley; Paul Greenfield; Mark I Bradbury; Ernest Lacey; Peter K Busk; Bo Pilgaard; Yit-Heng Chooi; Andrew M Piggott
Journal:  PLoS One       Date:  2017-04-05       Impact factor: 3.240

7.  Genome-Inspired Chemical Exploration of Marine Fungus Aspergillus fumigatus MF071.

Authors:  Jianying Han; Miaomiao Liu; Ian D Jenkins; Xueting Liu; Lixin Zhang; Ronald J Quinn; Yunjiang Feng
Journal:  Mar Drugs       Date:  2020-07-06       Impact factor: 5.118

8.  C7-Prenylation of Tryptophan-Containing Cyclic Dipeptides by 7-Dimethylallyl Tryptophan Synthase Significantly Increases the Anticancer and Antimicrobial Activities.

Authors:  Rui Liu; Hongchi Zhang; Weiqiang Wu; Hui Li; Zhipeng An; Feng Zhou
Journal:  Molecules       Date:  2020-08-12       Impact factor: 4.411

9.  Novel Prenylated Indole Alkaloids with Neuroprotection on SH-SY5Y Cells against Oxidative Stress Targeting Keap1-Nrf2.

Authors:  Xueyang Xiao; Zhou Tong; Yuexing Zhang; Hui Zhou; Mengying Luo; Tianhui Hu; Ping Hu; Luqi Kong; Zeqin Liu; Chan Yu; Zhiyong Huang; Linzhen Hu
Journal:  Mar Drugs       Date:  2022-03-04       Impact factor: 5.118
  9 in total

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