Literature DB >> 21062201

Self-reported changes in providers' hormone therapy prescribing and counseling practices after the Women's Health Initiative.

Susan L Lakey1, Susan D Reed, Andrea Z LaCroix, Lou Grothaus, Katherine M Newton.   

Abstract

BACKGROUND: Prescribing and counseling practices in hormone therapy (HT) since publication of the Women's Health Initiative (WHI) trials have changed. Our objective was to compare changes by practice field and region.
METHODS: Between December 2005 and May 2006, we mailed surveys to 938 practitioners from two large integrated health systems in the Northeastern and Northwestern United States. We received 736 responses and excluded 144 who do not prescribe/counsel about HT, leaving 592. Data included prescriber characteristics, knowledge about HT trials, and self-reported HT counseling and prescribing changes. We compared provider characteristics and HT counseling and prescribing by region and practice field (obstetrician/gynecology [OB/GYN] or primary care).
RESULTS: Respondents included 79 OB/GYNs and 513 primary care providers. OB/GYNs were more likely, than primary care providers to consider themselves experts regarding the Heart and Estrogen/progestin Replacement Study (HERS) and WHI trials (30.4% vs. 8.2%, p < 0.001). The majority (87%) were cautious about HT use, especially primary care providers (p < 0.01 compared to OB/GYNs). Respondents reported prescribing less oral unopposed estrogen (64%) and combination estrogen/progestin (81%) post-WHI. OB/GYNs were less likely to report decreases in oral unopposed estrogen use (p = 0.006). Use of lower-dose and transdermal products (low-dose estrogen, vaginal estrogen, estradiol vaginal ring) increased, especially by OB/GYNs.
CONCLUSIONS: Our study highlights numerous HT prescribing and counseling differences between primary care and OB/GYN providers. Reasons for these differences are unknown but may be related to self-reported WHI/HERS knowledge. HT formulations used in the WHI trials are being replaced by low-dose and alternate formulations. Studies to support this practice are needed.

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Year:  2010        PMID: 21062201      PMCID: PMC3003913          DOI: 10.1089/jwh.2010.2047

Source DB:  PubMed          Journal:  J Womens Health (Larchmt)        ISSN: 1540-9996            Impact factor:   2.681


  29 in total

1.  Hormone replacement therapy and cardiovascular disease: a statement for healthcare professionals from the American Heart Association.

Authors:  L Mosca; P Collins; D M Herrington; M E Mendelsohn; R C Pasternak; R M Robertson; K Schenck-Gustafsson; S C Smith ; K A Taubert; N K Wenger
Journal:  Circulation       Date:  2001-07-24       Impact factor: 29.690

2.  Prevalence of estrogen or estrogen-progestin hormone therapy use.

Authors:  Kate M Brett; Cynthia A Reuben
Journal:  Obstet Gynecol       Date:  2003-12       Impact factor: 7.661

Review 3.  Postmenopausal hormone replacement therapy and the primary prevention of cardiovascular disease.

Authors:  Linda L Humphrey; Benjamin K S Chan; Harold C Sox
Journal:  Ann Intern Med       Date:  2002-08-20       Impact factor: 25.391

4.  FDA orders estrogen safety warnings: agency offers guidance for HRT use.

Authors:  Joan Stephenson
Journal:  JAMA       Date:  2003-02-05       Impact factor: 56.272

5.  Physician specialty is significantly associated with hormone replacement therapy use.

Authors:  Barcey T Levy; Justine M Ritchie; Elaine Smith; Teresa Gray; Wei Zhang
Journal:  Obstet Gynecol       Date:  2003-01       Impact factor: 7.661

6.  What factors account for hormone replacement therapy prescribing frequency?

Authors:  K M Newton; A Z LaCroix; D S Buist; L A Anderson; K Delaney
Journal:  Maturitas       Date:  2001-07-25       Impact factor: 4.342

7.  Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial.

Authors:  Garnet L Anderson; Marian Limacher; Annlouise R Assaf; Tamsen Bassford; Shirley A A Beresford; Henry Black; Denise Bonds; Robert Brunner; Robert Brzyski; Bette Caan; Rowan Chlebowski; David Curb; Margery Gass; Jennifer Hays; Gerardo Heiss; Susan Hendrix; Barbara V Howard; Judith Hsia; Allan Hubbell; Rebecca Jackson; Karen C Johnson; Howard Judd; Jane Morley Kotchen; Lewis Kuller; Andrea Z LaCroix; Dorothy Lane; Robert D Langer; Norman Lasser; Cora E Lewis; JoAnn Manson; Karen Margolis; Judith Ockene; Mary Jo O'Sullivan; Lawrence Phillips; Ross L Prentice; Cheryl Ritenbaugh; John Robbins; Jacques E Rossouw; Gloria Sarto; Marcia L Stefanick; Linda Van Horn; Jean Wactawski-Wende; Robert Wallace; Sylvia Wassertheil-Smoller
Journal:  JAMA       Date:  2004-04-14       Impact factor: 56.272

8.  Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial.

Authors:  Jacques E Rossouw; Garnet L Anderson; Ross L Prentice; Andrea Z LaCroix; Charles Kooperberg; Marcia L Stefanick; Rebecca D Jackson; Shirley A A Beresford; Barbara V Howard; Karen C Johnson; Jane Morley Kotchen; Judith Ockene
Journal:  JAMA       Date:  2002-07-17       Impact factor: 56.272

9.  National use of postmenopausal hormone therapy: annual trends and response to recent evidence.

Authors:  Adam L Hersh; Marcia L Stefanick; Randall S Stafford
Journal:  JAMA       Date:  2004-01-07       Impact factor: 56.272

Review 10.  Issues to debate on the Women's Health Initiative (WHI) study. Prescription attitudes among Belgian gynaecologists after premature discontinuation of the WHI study.

Authors:  Graziella Ena; Serge Rozenberg
Journal:  Hum Reprod       Date:  2003-11       Impact factor: 6.918

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  1 in total

Review 1.  Postmenopausal hormone therapy is not associated with risk of all-cause dementia and Alzheimer's disease.

Authors:  Jacqueline O'Brien; John W Jackson; Francine Grodstein; Deborah Blacker; Jennifer Weuve
Journal:  Epidemiol Rev       Date:  2013-09-15       Impact factor: 6.222

  1 in total

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