| Literature DB >> 21062090 |
Dong Kee Yi1, In-Cheol Sun, Ju Hee Ryu, Heebeom Koo, Chul Wan Park, In-Chan Youn, Kuiwon Choi, Ick Chan Kwon, Kwangmeyung Kim, Cheol-Hee Ahn.
Abstract
Herein, we developed matrix metalloprotease (MMP) sensitive gold nanorods (MMP-AuNR) for cancer imaging and therapy. It was feasible to absorb NIR laser and convert into heat as well as visualize MMP activity. We showed the possibility of gold nanorods as a hyperthermal therapeutic agent and MMP sensitive imaging agent both in vitro and in vivo condition. The results suggested potential application of MMP-AuNR for simultaneous cancer diagnosis and therapy.Entities:
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Year: 2010 PMID： 21062090 DOI： 10.1021/bc100308p
Source DB: PubMed Journal: Bioconjug Chem ISSN： 1043-1802 Impact factor: 4.774