Literature DB >> 21060319

Farm living: effects on childhood asthma and allergy.

Erika von Mutius1, Donata Vercelli.   

Abstract

Numerous epidemiological studies have shown that children who grow up on traditional farms are protected from asthma, hay fever and allergic sensitization. Early-life contact with livestock and their fodder, and consumption of unprocessed cow's milk have been identified as the most effective protective exposures. Studies of the immunobiology of farm living point to activation and modulation of innate and adaptive immune responses by intense microbial exposures and possibly xenogeneic signals delivered before or soon after birth.

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Mesh：

Year:  2010        PMID： 21060319     DOI： 10.1038/nri2871

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  79 in total

1.  Reduced risk of hay fever and asthma among children of farmers.

Authors:  O S Von Ehrenstein; E Von Mutius; S Illi; L Baumann; O Böhm; R von Kries
Journal:  Clin Exp Allergy       Date:  2000-02       Impact factor: 5.018

2.  Effect of farming environment on sensitisation to allergens continues after childhood.

Authors:  H O Koskela; K K Happonen; S T Remes; J Pekkanen
Journal:  Occup Environ Med       Date:  2005-09       Impact factor: 4.402

3.  Cord blood cytokines are modulated by maternal farming activities and consumption of farm dairy products during pregnancy: the PASTURE Study.

Authors:  Petra Ina Pfefferle; Gisela Büchele; Nicole Blümer; Marjut Roponen; Markus Johannes Ege; Susanne Krauss-Etschmann; Jon Genuneit; Anne Hyvärinen; Maija-Riitta Hirvonen; Roger Lauener; Juha Pekkanen; Josef Riedler; Jean Charles Dalphin; Bert Brunekeef; Charlotte Braun-Fahrländer; Erika von Mutius; Harald Renz
Journal:  J Allergy Clin Immunol       Date:  2009-12-06       Impact factor: 10.793

4.  Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey.

Authors:  J Riedler; C Braun-Fahrländer; W Eder; M Schreuer; M Waser; S Maisch; D Carr; R Schierl; D Nowak; E von Mutius
Journal:  Lancet       Date:  2001-10-06       Impact factor: 79.321

5.  Inhalation of stable dust extract prevents allergen induced airway inflammation and hyperresponsiveness.

Authors:  M Peters; M Kauth; J Schwarze; C Körner-Rettberg; J Riedler; D Nowak; C Braun-Fahrländer; E von Mutius; A Bufe; O Holst
Journal:  Thorax       Date:  2005-10-21       Impact factor: 9.139

6.  Asthma in late adolescence--farm childhood is protective and the prevalence increase has levelled off.

Authors:  Göran Wennergren; Linda Ekerljung; Bernt Alm; Jonas Eriksson; Jan Lötvall; Bo Lundbäck
Journal:  Pediatr Allergy Immunol       Date:  2010-04-08       Impact factor: 6.377

7.  Interleukin 4 down-regulates the expression of CD14 in normal human monocytes.

Authors:  R P Lauener; S M Goyert; R S Geha; D Vercelli
Journal:  Eur J Immunol       Date:  1990-11       Impact factor: 5.532

8.  Exposure to animals and risk of oligoarticular juvenile idiopathic arthritis: a multicenter case-control study.

Authors:  Katja Radon; Doris Windstetter; David Poluda; Renate Häfner; Silke Thomas; Hartmut Michels; Erika von Mutius
Journal:  BMC Musculoskelet Disord       Date:  2010-04-20       Impact factor: 2.362

9.  Microbial exposure of rural school children, as assessed by levels of N-acetyl-muramic acid in mattress dust, and its association with respiratory health.

Authors:  Robert Theodoor van Strien; Regina Engel; Otto Holst; Albrecht Bufe; Waltraud Eder; Marco Waser; Charlotte Braun-Fahrländer; Josef Riedler; Dennis Nowak; Erika von Mutius
Journal:  J Allergy Clin Immunol       Date:  2004-05       Impact factor: 10.793

10.  Low IFN-gamma production in the first year of life as a predictor of wheeze during childhood.

Authors:  Debra A Stern; Stefano Guerra; Marilyn Halonen; Anne L Wright; Fernando D Martinez
Journal:  J Allergy Clin Immunol       Date:  2007-08-08       Impact factor: 10.793
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  192 in total

Review 1.  The impact of perinatal immune development on mucosal homeostasis and chronic inflammation.

Authors:  Harald Renz; Per Brandtzaeg; Mathias Hornef
Journal:  Nat Rev Immunol       Date:  2011-12-09       Impact factor: 53.106

2.  Regulatory T cells and regulation of allergic airway disease.

Authors:  Helen Martin; Christian Taube
Journal:  Am J Clin Exp Immunol       Date:  2012-11-15

Review 3.  Innate and adaptive immune responses in asthma.

Authors:  Stephen T Holgate
Journal:  Nat Med       Date:  2012-05-04       Impact factor: 53.440

4.  Continental-scale distributions of dust-associated bacteria and fungi.

Authors:  Albert Barberán; Joshua Ladau; Jonathan W Leff; Katherine S Pollard; Holly L Menninger; Robert R Dunn; Noah Fierer
Journal:  Proc Natl Acad Sci U S A       Date:  2015-04-20       Impact factor: 11.205

5.  Household siblings and nasal and fecal microbiota in infants.

Authors:  Kohei Hasegawa; Rachel W Linnemann; Jonathan M Mansbach; Nadim J Ajami; Janice A Espinola; Lauren G Fiechtner; Joseph F Petrosino; Carlos A Camargo
Journal:  Pediatr Int       Date:  2016-12-22       Impact factor: 1.524

Review 6.  The relationships between environmental bacterial exposure, airway bacterial colonization, and asthma.

Authors:  Avraham Beigelman; George M Weinstock; Leonard B Bacharier
Journal:  Curr Opin Allergy Clin Immunol       Date:  2014-04

Review 7.  The genetics of asthma and allergic disease: a 21st century perspective.

Authors:  Carole Ober; Tsung-Chieh Yao
Journal:  Immunol Rev       Date:  2011-07       Impact factor: 12.988

Review 8.  Gene-environment interactions in chronic inflammatory disease.

Authors:  Harald Renz; Erika von Mutius; Per Brandtzaeg; William O Cookson; Ingo B Autenrieth; Dirk Haller
Journal:  Nat Immunol       Date:  2011-04       Impact factor: 25.606

Review 9.  Asthma: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.

Authors:  Daniel J Jackson; Tina V Hartert; Fernando D Martinez; Scott T Weiss; John V Fahy
Journal:  Ann Am Thorac Soc       Date:  2014-04

Review 10.  Regulation of inflammation by microbiota interactions with the host.

Authors:  J Magarian Blander; Randy S Longman; Iliyan D Iliev; Gregory F Sonnenberg; David Artis
Journal:  Nat Immunol       Date:  2017-07-19       Impact factor: 25.606
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