Literature DB >> 2105172

An analysis of the cost effectiveness of the implantable defibrillator.

M Kuppermann1, B R Luce, B McGovern, P J Podrid, J T Bigger, J N Ruskin.   

Abstract

The automatic implantable defibrillator has been shown to decrease the mortality of patients who have survived cardiac arrest due to ventricular tachycardia or fibrillation and are at high risk for recurrence. We performed a cost-effectiveness analysis of this seemingly expensive new technology with data obtained from the 1984 Medicare data base, the medical literature, Medicare carriers, individual pharmacies and hospitals, and expert opinion. Analyzing combinations of principal and secondary discharge diagnoses across 18 diagnosis-related groups, we estimated the cost of hospitalization for a comparison group of patients. Hospitalization costs for the defibrillator group were obtained from reported empirical data. Rehospitalization rates and other health-care use estimates were solicited from an expert panel of physicians, and mortality rates for both groups were obtained from the literature. Using a decision-analytic model, we estimated that the net cost effectiveness of the defibrillator, when used in the high-risk patient, is approximately $17,100 per life-year saved, with sensitivity analyses suggesting that the true value lies between $15,000 and $25,000. This estimate is well within the range that is currently accepted by the US medical care system for other life-saving interventions. We also estimated the cost effectiveness of the defibrillator in a 1991 scenario to be $7,400 per life-year saved, when the device would have greater longevity, would be programmable, and would not require a thoracotomy. Sensitivity analyses suggest that the true value lies between a value that is cost saving (less expensive than pharmacologic therapy) and $19,600 per life-year saved.

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Mesh:

Year:  1990        PMID: 2105172     DOI: 10.1161/01.cir.81.1.91

Source DB:  PubMed          Journal:  Circulation        ISSN: 0009-7322            Impact factor:   29.690


  11 in total

1.  Audit of implantable cardioverter-defibrillators in a single UK centre.

Authors:  S Gupta; H Hasan; O Valencia; S Jones; E Rowland; A J Camm; C W Pumphrey; D E Ward
Journal:  BMJ       Date:  1999-05-22

2.  Pharmacoeconomic considerations in antiarrhythmic therapy.

Authors:  P J Podrid; R J Arnold; D J Kaniecki
Journal:  Pharmacoeconomics       Date:  1992-12       Impact factor: 4.981

3.  Experience with unipolar pectoral defibrillation.

Authors:  R K Reddy; G H Bardy
Journal:  Herzschrittmacherther Elektrophysiol       Date:  1997-03

4.  Life at a price: the implantable defibrillator.

Authors:  A J Camm; M Anderson
Journal:  Br Heart J       Date:  1991-04

5.  Health-related quality of life assessment and the pharmaceutical industry.

Authors:  D A Revicki; M Rothman; B Luce
Journal:  Pharmacoeconomics       Date:  1992-06       Impact factor: 4.981

6.  Implications for present and future applications of the implantable cardioverter-defibrillator resulting from the use of a simple model of cost efficacy.

Authors:  M H Anderson; A J Camm
Journal:  Br Heart J       Date:  1993-01

7.  Use of the implantable defibrillator.

Authors:  S C Hammil; M S Stanton
Journal:  Br Heart J       Date:  1995-01

8.  Florid psychopathology in patients receiving shocks from implanted cardioverter-defibrillators.

Authors:  J P Bourke; D Turkington; G Thomas; J M McComb; M Tynan
Journal:  Heart       Date:  1997-12       Impact factor: 5.994

Review 9.  Cost effectiveness of implantable cardioverter defibrillator therapy versus drug therapy for patients at high risk of sudden cardiac death.

Authors:  Marian A Spath; Bernie J O'Brien
Journal:  Pharmacoeconomics       Date:  2002       Impact factor: 4.981

10.  Cost effectiveness of the implantable cardioverter defibrillator: a preliminary analysis.

Authors:  B J O'Brien; M J Buxton; J A Rushby
Journal:  Br Heart J       Date:  1992-08
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