| Literature DB >> 21049974 |
Ernest H L Tee1, Tomislav Karoli, Soumya Ramu, Johnny X Huang, Mark S Butler, Matthew A Cooper.
Abstract
The triazolopyrimidine natural product essramycin (1) was synthesized without the use of protecting groups via a two-step reaction scheme involving a 3-amino-1,2,4-triazole intermediate, and its structure was unequivocally determined. However, in contrast to the natural product, the synthetic essramycin (1) did not display any antibacterial activity.Entities:
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Year: 2010 PMID： 21049974 DOI： 10.1021/np100648q
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050