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Literature DB >> 21049956

Nanostructure-initiator mass spectrometry metabolite analysis and imaging.

Matthew P Greving¹, Gary J Patti, Gary Siuzdak.

Abstract

Nanostructure-Initiator Mass Spectrometry (NIMS) is a matrix-free desorption/ionization approach that is particularly well-suited for unbiased (untargeted) metabolomics. An overview of the NIMS technology and its application in the detection of biofluid and tissue metabolites are presented. (To listen to a podcast about this feature, please go to the Analytical Chemistry multimedia page at pubs.acs.org/page/ancham/audio/index.html .).

Entities: Chemical Disease Gene Species

Mesh：

Year: 2010 PMID： 21049956 PMCID： PMC3012143 DOI： 10.1021/ac101565f

Source DB: PubMed Journal: Anal Chem ISSN： 0003-2700 Impact factor: 6.986

43 in total

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Review 2. Single-cell MALDI: a new tool for direct peptide profiling.

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3. Direct tissue analysis using matrix-assisted laser desorption/ionization mass spectrometry: practical aspects of sample preparation.

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4. Clinical proteomics: written in blood.

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Journal: Proc Natl Acad Sci U S A Date: 2008-08-12 Impact factor: 11.205

8. Matrix vapor deposition/recrystallization and dedicated spray preparation for high-resolution scanning microprobe matrix-assisted laser desorption/ionization imaging mass spectrometry (SMALDI-MS) of tissue and single cells.

Authors: Werner Bouschen; Oliver Schulz; Daniel Eikel; Bernhard Spengler
Journal: Rapid Commun Mass Spectrom Date: 2010-02 Impact factor: 2.419

9. Desorption/ionization on silicon (DIOS): a diverse mass spectrometry platform for protein characterization.

Authors: J J Thomas; Z Shen; J E Crowell; M G Finn; G Siuzdak
Journal: Proc Natl Acad Sci U S A Date: 2001-04-10 Impact factor: 11.205

10. Matrix-assisted laser desorption/ionization imaging mass spectrometry for direct measurement of clozapine in rat brain tissue.

Authors: Yunsheng Hsieh; Roger Casale; Elaine Fukuda; Jiwen Chen; Ian Knemeyer; Julia Wingate; Richard Morrison; Walter Korfmacher
Journal: Rapid Commun Mass Spectrom Date: 2006 Impact factor: 2.419

29 in total

Review 1. Nanostructure imaging mass spectrometry: the role of fluorocarbons in metabolite analysis and yoctomole level sensitivity.

Authors: Michael E Kurczy; Trent R Northen; Sunia A Trauger; Gary Siuzdak
Journal: Methods Mol Biol Date: 2015

Review 2. Probing Metabolism in the Intact Retina Using Stable Isotope Tracers.

Authors: Jianhai Du; Jonathan D Linton; James B Hurley
Journal: Methods Enzymol Date: 2015-06-14 Impact factor: 1.600

3. Novel galvanic nanostructures of Ag and Pd for efficient laser desorption/ionization of low molecular weight compounds.

Authors: Yuliya E Silina; Florian Meier; Valeriy A Nebolsin; Marcus Koch; Dietrich A Volmer
Journal: J Am Soc Mass Spectrom Date: 2014-05 Impact factor: 3.109

4. Brain region mapping using global metabolomics.

Authors: Julijana Ivanisevic; Adrian A Epstein; Michael E Kurczy; Paul H Benton; Winnie Uritboonthai; Howard S Fox; Michael D Boska; Howard E Gendelman; Gary Siuzdak
Journal: Chem Biol Date: 2014-11-20

5. Reverse engineering biomolecular systems using -omic data: challenges, progress and opportunities.

Authors: Chang F Quo; Chanchala Kaddi; John H Phan; Amin Zollanvari; Mingqing Xu; May D Wang; Gil Alterovitz
Journal: Brief Bioinform Date: 2012-07 Impact factor: 11.622

6. Biomolecular imaging with a C60-SIMS/MALDI dual ion source hybrid mass spectrometer: instrumentation, matrix enhancement, and single cell analysis.

Authors: Eric J Lanni; Sage J B Dunham; Peter Nemes; Stanislav S Rubakhin; Jonathan V Sweedler
Journal: J Am Soc Mass Spectrom Date: 2014-09-03 Impact factor: 3.109

10. Qualitative and quantitative metabolomic investigation of single neurons by capillary electrophoresis electrospray ionization mass spectrometry.

Authors: Peter Nemes; Stanislav S Rubakhin; Jordan T Aerts; Jonathan V Sweedler
Journal: Nat Protoc Date: 2013-03-28 Impact factor: 13.491