Literature DB >> 21047263

The RecQ DNA helicases in DNA repair.

Kara A Bernstein1, Serge Gangloff, Rodney Rothstein.   

Abstract

The RecQ helicases are conserved from bacteria to humans and play a critical role in genome stability. In humans, loss of RecQ gene function is associated with cancer predisposition and/or premature aging. Recent experiments have shown that the RecQ helicases function during distinct steps during DNA repair; DNA end resection, displacement-loop (D-loop) processing, branch migration, and resolution of double Holliday junctions (dHJs). RecQ function in these different processing steps has important implications for its role in repair of double-strand breaks (DSBs) that occur during DNA replication and meiosis, as well as at specific genomic loci such as telomeres.

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Year:  2010        PMID： 21047263      PMCID： PMC4038414          DOI： 10.1146/annurev-genet-102209-163602

Source DB:  PubMed          Journal:  Annu Rev Genet        ISSN： 0066-4197            Impact factor:   16.830


  161 in total

1.  Oligomeric ring structure of the Bloom's syndrome helicase.

Authors:  J K Karow; R H Newman; P S Freemont; I D Hickson
Journal:  Curr Biol       Date:  1999-06-03       Impact factor: 10.834

2.  CHROMOSOMAL BREAKAGE IN A RARE AND PROBABLY GENETICALLY DETERMINED SYNDROME OF MAN.

Authors:  J GERMAN; R ARCHIBALD; D BLOOM
Journal:  Science       Date:  1965-04-23       Impact factor: 47.728

3.  An abnormal profile of DNA replication intermediates in Bloom's syndrome.

Authors:  U Lönn; S Lönn; U Nylen; G Winblad; J German
Journal:  Cancer Res       Date:  1990-06-01       Impact factor: 12.701

4.  The jmjN and jmjC domains of the yeast zinc finger protein Gis1 interact with 19 proteins involved in transcription, sumoylation and DNA repair.

Authors:  Susanna Tronnersjö; Christine Hanefalk; Darius Balciunas; Guo-Zhen Hu; Niklas Nordberg; Eva Murén; Hans Ronne
Journal:  Mol Genet Genomics       Date:  2006-10-17       Impact factor: 3.291

5.  Sgs1: a eukaryotic homolog of E. coli RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation.

Authors:  P M Watt; E J Louis; R H Borts; I D Hickson
Journal:  Cell       Date:  1995-04-21       Impact factor: 41.582

6.  Purification of two DNA-dependent adenosinetriphosphatases having DNA helicase activity from HeLa cells and comparison of the properties of the two enzymes.

Authors:  M Seki; J Yanagisawa; T Kohda; T Sonoyama; M Ui; T Enomoto
Journal:  J Biochem       Date:  1994-03       Impact factor: 3.387

7.  The Saccharomyces cerevisiae Sgs1 helicase efficiently unwinds G-G paired DNAs.

Authors:  H Sun; R J Bennett; N Maizels
Journal:  Nucleic Acids Res       Date:  1999-05-01       Impact factor: 16.971

8.  Functional interaction between the Werner Syndrome protein and DNA polymerase delta.

Authors:  A S Kamath-Loeb; E Johansson; P M Burgers; L A Loeb
Journal:  Proc Natl Acad Sci U S A       Date:  2000-04-25       Impact factor: 11.205

9.  Enhanced tumor formation in mice heterozygous for Blm mutation.

Authors:  Kathleen Heppner Goss; Mary A Risinger; Jennifer J Kordich; Maureen M Sanz; Joel E Straughen; Lisa E Slovek; Anthony J Capobianco; James German; Gregory P Boivin; Joanna Groden
Journal:  Science       Date:  2002-09-20       Impact factor: 47.728

10.  The fission yeast BLM homolog Rqh1 promotes meiotic recombination.

Authors:  Gareth A Cromie; Randy W Hyppa; Gerald R Smith
Journal:  Genetics       Date:  2008-06-18       Impact factor: 4.562
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  157 in total

1.  The RecQ4 orthologue Hrq1 is critical for DNA interstrand cross-link repair and genome stability in fission yeast.

Authors:  Lynda M Groocock; John Prudden; J Jefferson P Perry; Michael N Boddy
Journal:  Mol Cell Biol       Date:  2011-11-07       Impact factor: 4.272

2.  Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining.

Authors:  Anastazja Grabarz; Aurélia Barascu; Josée Guirouilh-Barbat; Bernard S Lopez
Journal:  Am J Cancer Res       Date:  2012-04-21       Impact factor: 6.166

3.  Synergic and opposing activities of thermophilic RecQ-like helicase and topoisomerase 3 proteins in Holliday junction processing and replication fork stabilization.

Authors:  Anna Valenti; Mariarita De Felice; Giuseppe Perugino; Anna Bizard; Marc Nadal; Mosè Rossi; Maria Ciaramella
Journal:  J Biol Chem       Date:  2012-06-21       Impact factor: 5.157

4.  RECQL5 has unique strand annealing properties relative to the other human RecQ helicase proteins.

Authors:  Prabhat Khadka; Deborah L Croteau; Vilhelm A Bohr
Journal:  DNA Repair (Amst)       Date:  2015-12-02

5.  Hrq1 facilitates nucleotide excision repair of DNA damage induced by 4-nitroquinoline-1-oxide and cisplatin in Saccharomyces cerevisiae.

Authors:  Do-Hee Choi; Moon-Hee Min; Min-Ji Kim; Rina Lee; Sung-Hun Kwon; Sung-Ho Bae
Journal:  J Microbiol       Date:  2014-03-29       Impact factor: 3.422

Review 6.  The role of post-translational modifications in fine-tuning BLM helicase function during DNA repair.

Authors:  Stefanie Böhm; Kara Anne Bernstein
Journal:  DNA Repair (Amst)       Date:  2014-08-24

Review 7.  Clinically Applicable Inhibitors Impacting Genome Stability.

Authors:  Anu Prakash; Juan F Garcia-Moreno; James A L Brown; Emer Bourke
Journal:  Molecules       Date:  2018-05-13       Impact factor: 4.411

8.  Resection activity of the Sgs1 helicase alters the affinity of DNA ends for homologous recombination proteins in Saccharomyces cerevisiae.

Authors:  Kara A Bernstein; Eleni P Mimitou; Michael J Mihalevic; Huan Chen; Ivana Sunjaveric; Lorraine S Symington; Rodney Rothstein
Journal:  Genetics       Date:  2013-10-04       Impact factor: 4.562

9.  Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling.

Authors:  Julia M Sidorova; Keffy Kehrli; Frances Mao; Raymond Monnat
Journal:  DNA Repair (Amst)       Date:  2012-12-17

10.  Hrq1 functions independently of Sgs1 to preserve genome integrity in Saccharomyces cerevisiae.

Authors:  Do-Hee Choi; Rina Lee; Sung-Hun Kwon; Sung-Ho Bae
Journal:  J Microbiol       Date:  2013-03-02       Impact factor: 3.422
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