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Literature DB >> 21045802

An age of fewer histones.

Abstract

Changes in chromatin structure are a conserved hallmark of ageing, and the mechanism driving these changes, as well as their functional significance, are heavily investigated. Loss of core histones is now observed in aged cells and may contribute to this phenomenon. Histone loss is coupled to cell division and seems to be triggered by telomeric DNA damage.

Mesh：

Substances：
Chromatin
Histones

Year: 2010 PMID： 21045802 DOI： 10.1038/ncb1110-1029

Source DB: PubMed Journal: Nat Cell Biol ISSN： 1465-7392 Impact factor: 28.824

16 in total

1. Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo.

Authors: Maarten Hoek; Bruce Stillman
Journal: Proc Natl Acad Sci U S A Date: 2003-09-30 Impact factor: 11.205

2. Increased cell-to-cell variation in gene expression in ageing mouse heart.

Authors: Rumana Bahar; Claudia H Hartmann; Karl A Rodriguez; Ashley D Denny; Rita A Busuttil; Martijn E T Dollé; R Brent Calder; Gary B Chisholm; Brad H Pollock; Christoph A Klein; Jan Vijg
Journal: Nature Date: 2006-06-22 Impact factor: 49.962

Review 3. The aging brain.

Authors: Bruce A Yankner; Tao Lu; Patrick Loerch
Journal: Annu Rev Pathol Date: 2008 Impact factor: 23.472

Review 4. Cellular senescence: when bad things happen to good cells.

Authors: Judith Campisi; Fabrizio d'Adda di Fagagna
Journal: Nat Rev Mol Cell Biol Date: 2007-09 Impact factor: 94.444

5. A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.

Authors: Laura J Niedernhofer; George A Garinis; Anja Raams; Astrid S Lalai; Andria Rasile Robinson; Esther Appeldoorn; Hanny Odijk; Roos Oostendorp; Anwaar Ahmad; Wibeke van Leeuwen; Arjan F Theil; Wim Vermeulen; Gijsbertus T J van der Horst; Peter Meinecke; Wim J Kleijer; Jan Vijg; Nicolaas G J Jaspers; Jan H J Hoeijmakers
Journal: Nature Date: 2006-12-21 Impact factor: 49.962

6. DNA damage induces downregulation of histone gene expression through the G1 checkpoint pathway.

Authors: Chuan Su; Guang Gao; Sandra Schneider; Christopher Helt; Carsten Weiss; Michael A O'Reilly; Dirk Bohmann; Jiyong Zhao
Journal: EMBO J Date: 2004-02-19 Impact factor: 11.598

7. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

Authors: Francis Rodier; Jean-Philippe Coppé; Christopher K Patil; Wieteke A M Hoeijmakers; Denise P Muñoz; Saba R Raza; Adam Freund; Eric Campeau; Albert R Davalos; Judith Campisi
Journal: Nat Cell Biol Date: 2009-07-13 Impact factor: 28.824

Review 8. The ageing epigenome: damaged beyond repair?

Authors: David A Sinclair; Philipp Oberdoerffer
Journal: Ageing Res Rev Date: 2009-05-09 Impact factor: 10.895

9. Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells.

Authors: Jorrit V Tjeertes; Kyle M Miller; Stephen P Jackson
Journal: EMBO J Date: 2009-04-30 Impact factor: 11.598

10. CBP/p300-mediated acetylation of histone H3 on lysine 56.

Authors: Chandrima Das; M Scott Lucia; Kirk C Hansen; Jessica K Tyler
Journal: Nature Date: 2009-03-08 Impact factor: 49.962

8 in total

Review 1. Chromatin dynamics in DNA double-strand break repair.

Authors: Lei Shi; Philipp Oberdoerffer
Journal: Biochim Biophys Acta Date: 2012-01-17

Review 2. Chromatin and nucleosome dynamics in DNA damage and repair.

Authors: Michael H Hauer; Susan M Gasser
Journal: Genes Dev Date: 2017-11-15 Impact factor: 11.361

3. Cellular response to moderate chromatin architectural defects promotes longevity.

Authors: Ruofan Yu; Luyang Sun; Yu Sun; Xin Han; Lidong Qin; Weiwei Dang
Journal: Sci Adv Date: 2019-07-10 Impact factor: 14.136

4. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin.

Authors: Baoxu Pang; Xiaohang Qiao; Lennert Janssen; Arno Velds; Tom Groothuis; Ron Kerkhoven; Marja Nieuwland; Huib Ovaa; Sven Rottenberg; Olaf van Tellingen; Jeroen Janssen; Peter Huijgens; Wilbert Zwart; Jacques Neefjes
Journal: Nat Commun Date: 2013 Impact factor: 14.919

5. Sustained activation of Akt elicits mitochondrial dysfunction to block Plasmodium falciparum infection in the mosquito host.

Authors: Shirley Luckhart; Cecilia Giulivi; Anna L Drexler; Yevgeniya Antonova-Koch; Danielle Sakaguchi; Eleonora Napoli; Sarah Wong; Mark S Price; Richard Eigenheer; Brett S Phinney; Nazzy Pakpour; Jose E Pietri; Kong Cheung; Martha Georgis; Michael Riehle
Journal: PLoS Pathog Date: 2013-02-28 Impact factor: 6.823