BACKGROUND: We investigated the usefulness of optical coherence tomography (OCT) to evaluate vessel response after stent implantation by comparing with that of intravascular ultrasound (IVUS). METHODS AND RESULTS: Eighteen cases undergoing percutaneous coronary intervention (PCI) who provided consent for both IVUS and OCT usage pre- and post-PCI procedure were enrolled. The lumen area at the distal site of the culprit lesion was smaller on OCT images than on IVUS images due to proximal vessel occlusion, whereas the lumen area at the proximal site of the lesion did not differ between OCT and IVUS images (distal site: 4.6 ± 2.0 vs. 5.0 ± 1.8 mm²; p = 0.0004; proximal site: 5.5 ± 2.3 vs. 5.6 ± 2.3 mm²; p = 0.8160). Stent malapposition was more frequently observed by OCT (30%) than by IVUS (5%, p = 0.0381). Stent edge dissection was not detected by IVUS, but was detected in 10% by OCT. Tissue prolapse was identified in all stents by OCT and in 5% by IVUS. Thrombus was observed in 15% by OCT and in 5% by IVUS. CONCLUSIONS: Proximal coronary occlusion during OCT imaging was possibly related to underestimation of vessel sizing at distal reference. Our data suggested that OCT might provide more detailed information on the presence of tissue prolapse, thrombus formation and edge dissection than IVUS. Further study is warranted to assess its clinical utility.
BACKGROUND: We investigated the usefulness of optical coherence tomography (OCT) to evaluate vessel response after stent implantation by comparing with that of intravascular ultrasound (IVUS). METHODS AND RESULTS: Eighteen cases undergoing percutaneous coronary intervention (PCI) who provided consent for both IVUS and OCT usage pre- and post-PCI procedure were enrolled. The lumen area at the distal site of the culprit lesion was smaller on OCT images than on IVUS images due to proximal vessel occlusion, whereas the lumen area at the proximal site of the lesion did not differ between OCT and IVUS images (distal site: 4.6 ± 2.0 vs. 5.0 ± 1.8 mm²; p = 0.0004; proximal site: 5.5 ± 2.3 vs. 5.6 ± 2.3 mm²; p = 0.8160). Stent malapposition was more frequently observed by OCT (30%) than by IVUS (5%, p = 0.0381). Stent edge dissection was not detected by IVUS, but was detected in 10% by OCT. Tissue prolapse was identified in all stents by OCT and in 5% by IVUS. Thrombus was observed in 15% by OCT and in 5% by IVUS. CONCLUSIONS: Proximal coronary occlusion during OCT imaging was possibly related to underestimation of vessel sizing at distal reference. Our data suggested that OCT might provide more detailed information on the presence of tissue prolapse, thrombus formation and edge dissection than IVUS. Further study is warranted to assess its clinical utility.
Authors: Gregory T Stefano; Hiram G Bezerra; Emile Mehanna; Hirosada Yamamoto; Yusuke Fujino; Wei Wang; Guilherme Attizzani; Daniel Chamié; Daniel I Simon; Marco A Costa Journal: Int J Cardiovasc Imaging Date: 2012-10-12 Impact factor: 2.357
Authors: Francesco Burzotta; Antonio Maria Leone; Giovanni Luigi De Maria; Giampaolo Niccoli; Valentina Coluccia; Giancarlo Pirozzolo; Silvia Saffioti; Cristina Aurigemma; Carlo Trani; Filippo Crea Journal: Trials Date: 2014-04-23 Impact factor: 2.279
Authors: Marta Francesca Brancati; Francesco Burzotta; Carlo Trani; Ornella Leonzi; Claudio Cuccia; Filippo Crea Journal: Pragmat Obs Res Date: 2017-07-13