| Literature DB >> 21041318 |
M Figueiredo1, S Lane, F Tang, B H Liu, J Hewinson, N Marina, V Kasymov, E A Souslova, D M Chudakov, A V Gourine, A G Teschemacher, S Kasparov.
Abstract
We briefly review the current literature where optogenetics has been used to study various aspects of astrocyte physiology in vitro and in vivo. This includes both genetically engineered Ca(2+) sensors and effector proteins, such as channelrhodopsin. We demonstrate how the ability to target astrocytes with cell-specific viral vectors to express optogenetic constructs helped to unravel some previously unsuspected roles of these inconspicuous cells.Entities:
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Year: 2010 PMID： 21041318 DOI： 10.1113/expphysiol.2010.052597
Source DB: PubMed Journal: Exp Physiol ISSN： 0958-0670 Impact factor: 2.969