AIMS: The present study evaluated the relationship between metabolic syndrome (MS), body fat composition and epicardial adipose tissue (EAT) in type 1 diabetes. Epicardial adipose tissue is a new independent marker of coronary artery disease (CAD). METHODS: forty-five type 1 diabetic women were evaluated (age 36 ± 9 years; body mass index 24.6 ± 4.4 kg/m(2)). Metabolic syndrome was defined by the World Health Organization criteria. Body fat composition and EAT were analyzed by dual-energy-X-ray absorptiometry and echocardiogram, respectively. RESULTS: twenty patients (45%) had MS. Patients with MS had greater android (central) fat deposition than patients without MS (41.9 ± 2.0% vs. 33.7 ± 1.8%, p=0.004). Total body fat and gynoid (peripheric) fat distribution were similar between the groups. Mean EAT was higher in patients with MS (6.15 ± 0.34 mm vs. 4.96 ± 0.25 mm; p=0.006) and EAT was positively correlated with android (central) fat distribution (r=0.44; p=0.002), however no correlation was found with gynoid (peripheric) fat distribution. CONCLUSIONS: there was a high incidence of MS in type 1 diabetes related to increased central adiposity, despite the absence of obesity. Metabolic syndrome and central obesity were associated with increased EAT. Thus, young non-obese type 1 diabetic women with central adiposity and/or MS may have increased EAT, what may predict CAD risk. 2010 Elsevier Ireland Ltd. All rights reserved.
AIMS: The present study evaluated the relationship between metabolic syndrome (MS), body fat composition and epicardial adipose tissue (EAT) in type 1 diabetes. Epicardial adipose tissue is a new independent marker of coronary artery disease (CAD). METHODS: forty-five type 1 diabeticwomen were evaluated (age 36 ± 9 years; body mass index 24.6 ± 4.4 kg/m(2)). Metabolic syndrome was defined by the World Health Organization criteria. Body fat composition and EAT were analyzed by dual-energy-X-ray absorptiometry and echocardiogram, respectively. RESULTS: twenty patients (45%) had MS. Patients with MS had greater android (central) fat deposition than patients without MS (41.9 ± 2.0% vs. 33.7 ± 1.8%, p=0.004). Total body fat and gynoid (peripheric) fat distribution were similar between the groups. Mean EAT was higher in patients with MS (6.15 ± 0.34 mm vs. 4.96 ± 0.25 mm; p=0.006) and EAT was positively correlated with android (central) fat distribution (r=0.44; p=0.002), however no correlation was found with gynoid (peripheric) fat distribution. CONCLUSIONS: there was a high incidence of MS in type 1 diabetes related to increased central adiposity, despite the absence of obesity. Metabolic syndrome and central obesity were associated with increased EAT. Thus, young non-obese type 1 diabeticwomen with central adiposity and/or MS may have increased EAT, what may predict CAD risk. 2010 Elsevier Ireland Ltd. All rights reserved.
Authors: Harshal R Patil; Nirav T Patil; Samantha I King; Evan O'Keefe; Rajiv Chhabra; Shaya Ansari; Kevin F Kennedy; Damini Dey; James H O'Keefe; John H Helzberg; Randall C Thompson Journal: J Nucl Cardiol Date: 2014-08-16 Impact factor: 5.952
Authors: O C Santos; N A O Silva; M Vaisman; M D Turano; M G Dytz; G A Huber; V B Braulio; P F S Teixeira Journal: J Endocrinol Invest Date: 2014-10-29 Impact factor: 4.256
Authors: Daniela Bertol Graeff; Murilo Foppa; Julio Cesar Gall Pires; Alvaro Vigo; Maria Ines Schmidt; Paulo Andrade Lotufo; Jose Geraldo Mill; Bruce Bartholow Duncan Journal: Int J Cardiovasc Imaging Date: 2015-11-19 Impact factor: 2.357
Authors: Umjeet S Jolly; Abraam Soliman; Charles McKenzie; Terry Peters; John Stirrat; Immaculate Nevis; Matthew Brymer; Tisha Joy; Maria Drangova; James A White Journal: J Cardiovasc Magn Reson Date: 2013-09-10 Impact factor: 5.364