Chaehun Lim1, Myeong-Im Ahn2, Jung Im Jung3, Kyongmin Sarah Beck3. 1. Department of Radiology, Medicheck Health Care Gangnam Center, 269 Olympic-ro, Songpa-gu, Seoul, 05510, South Korea. 2. Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 06591, South Korea. ami@catholic.ac.kr. 3. Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul, 06591, South Korea.
Abstract
PURPOSE: To assess the usefulness of simple axial bi-dimensional diameters of pericardial fat tissues at low-dose chest CT, in correlation with metabolic parameters in predicting metabolic syndrome. MATERIALS AND METHODS: Subjects were 373 asymptomatic individuals who performed both low-dose chest CT and abdominal fat CT for medical check-up. Maximum bi-dimensional axial diameters of paracardial fats at right (RPF) and left (LPF) cardiophrenic angle portions, and epicardial fats around right (REF) and left (LEF) coronary arteries, and coronary sinus (SEF) were measured. Correlation between pericardial fat diameters and metabolic parameters were statistically analyzed. RESULTS: RPF, LPF, REF, LEF, and SEF diameters were moderately correlated with abdominal visceral fat (AVF) area (R = 0.74, 0.70, 0.48, 0.41, and 0.53, respectively, p < 0.01) in Pearson's correlation analysis. In multiple linear regression analysis, coefficient of RPF for AVF showed highest value. Means of each PF and EF diameters in subjects with metabolic syndrome were significantly larger than those without metabolic syndrome (p < 0.001). All PF and EF diameters were well-discriminated for prediction of metabolic syndrome in ROC analysis (AUC values, from 0.696 to 0.795). CONCLUSION: RPF diameter at low-dose chest CT would be a simple method for prediction of metabolic syndrome.
PURPOSE: To assess the usefulness of simple axial bi-dimensional diameters of pericardial fat tissues at low-dose chest CT, in correlation with metabolic parameters in predicting metabolic syndrome. MATERIALS AND METHODS: Subjects were 373 asymptomatic individuals who performed both low-dose chest CT and abdominal fat CT for medical check-up. Maximum bi-dimensional axial diameters of paracardial fats at right (RPF) and left (LPF) cardiophrenic angle portions, and epicardial fats around right (REF) and left (LEF) coronary arteries, and coronary sinus (SEF) were measured. Correlation between pericardial fat diameters and metabolic parameters were statistically analyzed. RESULTS: RPF, LPF, REF, LEF, and SEF diameters were moderately correlated with abdominal visceral fat (AVF) area (R = 0.74, 0.70, 0.48, 0.41, and 0.53, respectively, p < 0.01) in Pearson's correlation analysis. In multiple linear regression analysis, coefficient of RPF for AVF showed highest value. Means of each PF and EF diameters in subjects with metabolic syndrome were significantly larger than those without metabolic syndrome (p < 0.001). All PF and EF diameters were well-discriminated for prediction of metabolic syndrome in ROC analysis (AUC values, from 0.696 to 0.795). CONCLUSION: RPF diameter at low-dose chest CT would be a simple method for prediction of metabolic syndrome.
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