Miwako Kimura1, Ted Mau, Roger W Chan. 1. Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390-9035, USA.
Abstract
OBJECTIVE: To evaluate the in vitro rheometric properties of the canine vocal fold lamina propria and muscle at phonatory frequencies, and their changes with anatomic location. METHODS: Six canine larynges were harvested immediately postmortem. Viscoelastic shear properties of anterior, middle, and posterior portions of the vocal fold cover (lamina propria) as well as those of the medial thyroarytenoid (TA) muscle (vocalis muscle) were quantified by a linear, controlled-strain simple-shear rheometer. Measurements of elastic shear modulus (G') and dynamic viscosity (η') of the specimens were conducted with small-amplitude sinusoidal shear deformation over a frequency range of 1-250Hz. RESULTS: All specimens showed similar frequency dependence of the viscoelastic functions, with G' gradually increasing with frequency and η' decreasing with frequency monotonically. G' and η' of the canine vocalis muscle were significantly higher than those of the canine vocal fold cover, and η' of the canine vocal fold cover was significantly higher than that of the human vocal fold cover. There were no significant differences in G' and in η' between different portions of the canine vocal fold cover. CONCLUSION: These preliminary data based on the canine model suggested that the vocalis muscle, while in a relaxed state in vitro, is significantly stiffer and more viscous than the vocal fold cover during vibration at phonatory frequencies. For large-amplitude vocal fold vibration involving the medial portion of the TA muscle, such distinct differences in viscoelastic properties of different layers of the vocal fold should be taken into account in multi-layered biomechanical models of phonation.
OBJECTIVE: To evaluate the in vitro rheometric properties of the canine vocal fold lamina propria and muscle at phonatory frequencies, and their changes with anatomic location. METHODS: Six canine larynges were harvested immediately postmortem. Viscoelastic shear properties of anterior, middle, and posterior portions of the vocal fold cover (lamina propria) as well as those of the medial thyroarytenoid (TA) muscle (vocalis muscle) were quantified by a linear, controlled-strain simple-shear rheometer. Measurements of elastic shear modulus (G') and dynamic viscosity (η') of the specimens were conducted with small-amplitude sinusoidal shear deformation over a frequency range of 1-250Hz. RESULTS: All specimens showed similar frequency dependence of the viscoelastic functions, with G' gradually increasing with frequency and η' decreasing with frequency monotonically. G' and η' of the canine vocalis muscle were significantly higher than those of the canine vocal fold cover, and η' of the canine vocal fold cover was significantly higher than that of the human vocal fold cover. There were no significant differences in G' and in η' between different portions of the canine vocal fold cover. CONCLUSION: These preliminary data based on the canine model suggested that the vocalis muscle, while in a relaxed state in vitro, is significantly stiffer and more viscous than the vocal fold cover during vibration at phonatory frequencies. For large-amplitude vocal fold vibration involving the medial portion of the TA muscle, such distinct differences in viscoelastic properties of different layers of the vocal fold should be taken into account in multi-layered biomechanical models of phonation.
Authors: Mariah S Hahn; James B Kobler; Barry C Starcher; Steven M Zeitels; Robert Langer Journal: Ann Otol Rhinol Laryngol Date: 2006-02 Impact factor: 1.547
Authors: Gregory R Dion; Seema Jeswani; Scott Roof; Mark Fritz; Paulo G Coelho; Michael Sobieraj; Milan R Amin; Ryan C Branski Journal: Mater Sci Eng C Mater Biol Appl Date: 2016-04-08 Impact factor: 7.328