OBJECTIVE: "Do Bugs Need Drugs" (DBND) is a community education program that was implemented in British Columbia (BC) in September 2005 to decrease inappropriate antibiotic use. This study conducted descriptive analyses of the association between DBND and changes in overall, pediatric, drug-specific, and indication-specific antibiotic utilization rates in Vancouver, BC. METHODS: Utilization data on all oral solid and liquid antibiotics classified as "antibacterials for systemic use" were obtained from BC PharmaNet for the years 1996 to 2008. Utilization data were linked to physician billing data to allow indication-specific analyses. Following conversion to the defined daily dose (DDD), the Holt-Winters exponential smoothing method was used to project expected antibiotic use in the period after implementation based on use prior to implementation. Differences between expected and observed utilization rates were calculated. RESULTS: Overall antibiotic use has stabilized in recent years (16.2 DDD/1000 population/day in 2008). Fluoroquinolone use remains high (1.5 DDD/1000 population/day), as does the steadily increasing use of newer macrolides (1.1 to 2.7 DDD/1000 population/day between 1996 and 2008). Encouraging declines in overall and indication-specific prescription rates among children were observed. Following 3 years of DBND activities, antibiotic use was 5.8% lower than expected and the number of prescriptions dispensed to children was 10.6% lower than expected. CONCLUSIONS: This ecological study reports improvements in antibiotic use that occurred simultaneously to the delivery of the DBND program in Vancouver. However, we did not find a lowering of all targeted classes. Policy directives limiting the use of certain antibiotics may be required.
OBJECTIVE: "Do Bugs Need Drugs" (DBND) is a community education program that was implemented in British Columbia (BC) in September 2005 to decrease inappropriate antibiotic use. This study conducted descriptive analyses of the association between DBND and changes in overall, pediatric, drug-specific, and indication-specific antibiotic utilization rates in Vancouver, BC. METHODS: Utilization data on all oral solid and liquid antibiotics classified as "antibacterials for systemic use" were obtained from BC PharmaNet for the years 1996 to 2008. Utilization data were linked to physician billing data to allow indication-specific analyses. Following conversion to the defined daily dose (DDD), the Holt-Winters exponential smoothing method was used to project expected antibiotic use in the period after implementation based on use prior to implementation. Differences between expected and observed utilization rates were calculated. RESULTS: Overall antibiotic use has stabilized in recent years (16.2 DDD/1000 population/day in 2008). Fluoroquinolone use remains high (1.5 DDD/1000 population/day), as does the steadily increasing use of newer macrolides (1.1 to 2.7 DDD/1000 population/day between 1996 and 2008). Encouraging declines in overall and indication-specific prescription rates among children were observed. Following 3 years of DBND activities, antibiotic use was 5.8% lower than expected and the number of prescriptions dispensed to children was 10.6% lower than expected. CONCLUSIONS: This ecological study reports improvements in antibiotic use that occurred simultaneously to the delivery of the DBND program in Vancouver. However, we did not find a lowering of all targeted classes. Policy directives limiting the use of certain antibiotics may be required.
Authors: Rachel M McKay; Linda Vrbova; Elaine Fuertes; Mei Chong; Samara David; Kim Dreher; Dale Purych; Edith Blondel-Hill; Bonnie Henry; Fawziah Marra; Perry Rw Kendall; David M Patrick Journal: Can J Infect Dis Med Microbiol Date: 2011 Impact factor: 2.471
Authors: Tiscar Graells; Irene A Lambraki; Melanie Cousins; Anaïs Léger; Kate Lillepold; Patrik J G Henriksson; Max Troell; Carolee A Carson; Elizabeth Jane Parmley; Shannon E Majowicz; Didier Wernli; Peter Søgaard Jørgensen Journal: Antibiotics (Basel) Date: 2022-05-10
Authors: Susan Rogers Van Katwyk; Jeremy M Grimshaw; Miriam Nkangu; Ranjana Nagi; Marc Mendelson; Monica Taljaard; Steven J Hoffman Journal: PLoS Med Date: 2019-06-11 Impact factor: 11.069
Authors: Tara Gomes; Daniel McCormack; Sophie A Kitchen; J Michael Paterson; Muhammad M Mamdani; Laurie Proulx; Lorraine Bayliss; Mina Tadrous Journal: CMAJ Open Date: 2021-11-23