Literature DB >> 21031004

Understanding transport through pharmacological barriers--are we there yet?

Balázs Sarkadi, Gergely Szakács.   

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Year:  2010        PMID： 21031004     DOI： 10.1038/nrd3187-c1

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  10 in total

Review 1.  Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings.

Authors:  C A Lipinski; F Lombardo; B W Dominy; P J Feeney
Journal:  Adv Drug Deliv Rev       Date:  2001-03-01       Impact factor: 15.470

Review 2.  Is the multidrug transporter a flippase?

Authors:  C F Higgins; M M Gottesman
Journal:  Trends Biochem Sci       Date:  1992-01       Impact factor: 13.807

Review 3.  Coexistence of passive and carrier-mediated processes in drug transport.

Authors:  Kiyohiko Sugano; Manfred Kansy; Per Artursson; Alex Avdeef; Stefanie Bendels; Li Di; Gerhard F Ecker; Bernard Faller; Holger Fischer; Grégori Gerebtzoff; Hans Lennernaes; Frank Senner
Journal:  Nat Rev Drug Discov       Date:  2010-08       Impact factor: 84.694

Review 4.  Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?

Authors:  Paul D Dobson; Douglas B Kell
Journal:  Nat Rev Drug Discov       Date:  2008-03       Impact factor: 84.694

Review 5.  Membrane transporters in drug development.

Authors:  Kathleen M Giacomini; Shiew-Mei Huang; Donald J Tweedie; Leslie Z Benet; Kim L R Brouwer; Xiaoyan Chu; Amber Dahlin; Raymond Evers; Volker Fischer; Kathleen M Hillgren; Keith A Hoffmaster; Toshihisa Ishikawa; Dietrich Keppler; Richard B Kim; Caroline A Lee; Mikko Niemi; Joseph W Polli; Yuichi Sugiyama; Peter W Swaan; Joseph A Ware; Stephen H Wright; Sook Wah Yee; Maciej J Zamek-Gliszczynski; Lei Zhang
Journal:  Nat Rev Drug Discov       Date:  2010-03       Impact factor: 84.694

Review 6.  Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system.

Authors:  Balázs Sarkadi; László Homolya; Gergely Szakács; András Váradi
Journal:  Physiol Rev       Date:  2006-10       Impact factor: 37.312

Review 7.  Induction of phase I, II and III drug metabolism/transport by xenobiotics.

Authors:  Changjiang Xu; Christina Yong-Tao Li; Ah-Ng Tony Kong
Journal:  Arch Pharm Res       Date:  2005-03       Impact factor: 4.946

Review 8.  Targeting multidrug resistance in cancer.

Authors:  Gergely Szakács; Jill K Paterson; Joseph A Ludwig; Catherine Booth-Genthe; Michael M Gottesman
Journal:  Nat Rev Drug Discov       Date:  2006-03       Impact factor: 84.694

9.  Coordinated induction of drug transporters and phase I and II metabolism in human liver slices.

Authors:  P Olinga; M G L Elferink; A L Draaisma; M T Merema; J V Castell; G Pérez; G M M Groothuis
Journal:  Eur J Pharm Sci       Date:  2008-02-02       Impact factor: 4.384

10.  Nrf2 plays an important role in coordinated regulation of Phase II drug metabolism enzymes and Phase III drug transporters.

Authors:  Guoxiang Shen; Ah-Ng Kong
Journal:  Biopharm Drug Dispos       Date:  2009-10       Impact factor: 1.627
  10 in total
  6 in total

1.  The predictive value of ABCB1, ABCG2, CYP3A4/5 and CYP2D6 polymorphisms for risperidone and aripiprazole plasma concentrations and the occurrence of adverse drug reactions.

Authors:  C Rafaniello; M Sessa; F F Bernardi; M Pozzi; S Cheli; D Cattaneo; S Baldelli; M Molteni; R Bernardini; F Rossi; E Clementi; C Bravaccio; S Radice; A Capuano
Journal:  Pharmacogenomics J       Date:  2017-07-18       Impact factor: 3.550

2.  Human intestinal transporter database: QSAR modeling and virtual profiling of drug uptake, efflux and interactions.

Authors:  Alexander Sedykh; Denis Fourches; Jianmin Duan; Oliver Hucke; Michel Garneau; Hao Zhu; Pierre Bonneau; Alexander Tropsha
Journal:  Pharm Res       Date:  2012-12-27       Impact factor: 4.200

3.  A novel mathematical model describing adaptive cellular drug metabolism and toxicity in the chemoimmune system.

Authors:  Attila Tóth; Anna Brózik; Gergely Szakács; Balázs Sarkadi; Tamás Hegedüs
Journal:  PLoS One       Date:  2015-02-20       Impact factor: 3.240

Review 4.  Targeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance.

Authors:  Gergely Szakács; Matthew D Hall; Michael M Gottesman; Ahcène Boumendjel; Remy Kachadourian; Brian J Day; Hélène Baubichon-Cortay; Attilio Di Pietro
Journal:  Chem Rev       Date:  2014-04-23       Impact factor: 60.622

5.  Interactions of retinoids with the ABC transporters P-glycoprotein and Breast Cancer Resistance Protein.

Authors:  Szabolcs Tarapcsák; Gábor Szalóki; Ágnes Telbisz; Zsuzsanna Gyöngy; Krisztina Matúz; Éva Csősz; Péter Nagy; Imre J Holb; Ralph Rühl; László Nagy; Gábor Szabó; Katalin Goda
Journal:  Sci Rep       Date:  2017-02-01       Impact factor: 4.379

6.  Effects of Polyphenols on P-Glycoprotein (ABCB1) Activity.

Authors:  Kuljeet Singh; Szabolcs Tarapcsák; Zsuzsanna Gyöngy; Zsuzsanna Ritter; Gyula Batta; Rosevalentine Bosire; Judit Remenyik; Katalin Goda
Journal:  Pharmaceutics       Date:  2021-12-02       Impact factor: 6.321
  6 in total

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