Literature DB >> 21030195

Thirty-day mortality and late survival with reinterventions and readmissions after open and endovascular aortic aneurysm repair in Medicare beneficiaries.

Kristina A Giles1, Bruce E Landon, Philip Cotterill, A James O'Malley, Frank B Pomposelli, Marc L Schermerhorn.   

Abstract

OBJECTIVES: Late survival is similar after open and endovascular abdominal aortic aneurysm (AAA) repair (EVAR), despite a perioperative benefit with EVAR. AAA-related reinterventions are more common after EVAR, whereas laparotomy-related reinterventions are more common after open repair. The effect of reinterventions on survival, however, is unknown. We therefore evaluated the rate of reinterventions and readmission after initial AAA repair, 30-day mortality, and the effect on long-term survival.
METHODS: We identified AAA-related and laparotomy-related reinterventions for propensity score-matched cohorts of 45,652 Medicare beneficiaries undergoing EVAR and open repair from 2001 to 2004. Follow-up was up to 6 years. Hospitalizations for ruptured AAA without repair and for bowel obstruction or ventral hernia without abdominal surgery were also recorded. Event rates were calculated per year and are presented through 6 years of follow-up as events per 100 person-years. Thirty-day mortality was calculated for each reintervention or readmission.
RESULTS: Through 6 years, overall reinterventions or readmissions were similar between repair methods but slightly more common after EVAR (7.6 vs 7.0/100 person-years; relative risk [RR], 1.1; P < .001). Overall 30-day mortality with any reintervention or readmission was 9.1%. EVAR patients had more ruptures (0.50 vs 0.09 [RR, 5.7; P < .001]), with a mortality of 28%, but these were uncommon. EVAR patients also had more AAA-related reinterventions through 6 years (3.7 vs 0.9 [RR, 4.0; P < .001]; mortality, 5.6%), most of which were minor endovascular reinterventions (2.4 vs 0.2 [RR, 11.4; P < .001]), with a 30-day mortality of 3.0%. However, minor open (0.8 vs 0.5 [RR, 1.4; P < .001]; mortality, 6.9%) and major reinterventions (0.4 vs 0.2 [RR, 2.4; P < .001]; mortality, 12.1%) were also more common after EVAR than open repair. Conversely, EVAR patients had fewer laparotomy-related reinterventions than open patients (1.4 vs 3.0 [RR, 0.5; P < .001]; mortality, 8.1%) and readmissions without surgery (2.0 vs 2.7 [RR, 0.7; P < .001]; mortality 10.9%). Overall, reinterventions or readmission accounted for 9.6% of all EVAR deaths and 7.6% of all open repair deaths in the follow-up period (P < .001).
CONCLUSIONS: Reintervention and readmission are slightly higher after EVAR. Survival is negatively affected by reintervention or readmission after EVAR and open surgery, which likely contributes to the erosion of the survival benefit of EVAR over time.
Copyright © 2011 Society for Vascular Surgery. Published by Mosby, Inc. All rights reserved.

Entities:  

Mesh:

Year:  2010        PMID: 21030195      PMCID: PMC3010445          DOI: 10.1016/j.jvs.2010.08.051

Source DB:  PubMed          Journal:  J Vasc Surg        ISSN: 0741-5214            Impact factor:   4.268


  14 in total

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2.  Risk-adjusted outcome analysis of endovascular abdominal aortic aneurysm repair in a large population: how do stent-grafts compare?

Authors:  Corine J van Marrewijk; Lina J Leurs; Srinivasa R Vallabhaneni; Peter L Harris; Jacob Buth; Robert J F Laheij
Journal:  J Endovasc Ther       Date:  2005-08       Impact factor: 3.487

3.  Should usual criteria for intervention in abdominal aortic aneurysms be "downsized," considering reported risk reduction with endovascular repair?

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Journal:  Ann N Y Acad Sci       Date:  2006-11       Impact factor: 5.691

4.  Long-term outcomes after endovascular abdominal aortic aneurysm repair: the first decade.

Authors:  David C Brewster; John E Jones; Thomas K Chung; Glenn M Lamuraglia; Christopher J Kwolek; Michael T Watkins; Thomas M Hodgman; Richard P Cambria
Journal:  Ann Surg       Date:  2006-09       Impact factor: 12.969

5.  Endovascular aneurysm repair versus open repair in patients with abdominal aortic aneurysm (EVAR trial 1): randomised controlled trial.

Authors: 
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6.  Incidence and risk factors of late rupture, conversion, and death after endovascular repair of infrarenal aortic aneurysms: the EUROSTAR experience. European Collaborators on Stent/graft techniques for aortic aneurysm repair.

Authors:  P L Harris; S R Vallabhaneni; P Desgranges; J P Becquemin; C van Marrewijk; R J Laheij
Journal:  J Vasc Surg       Date:  2000-10       Impact factor: 4.268

7.  Two-year outcomes after conventional or endovascular repair of abdominal aortic aneurysms.

Authors:  Jan D Blankensteijn; Sjors E C A de Jong; Monique Prinssen; Arie C van der Ham; Jaap Buth; Steven M M van Sterkenburg; Hence J M Verhagen; Erik Buskens; Diederick E Grobbee
Journal:  N Engl J Med       Date:  2005-06-09       Impact factor: 91.245

8.  A randomized trial comparing conventional and endovascular repair of abdominal aortic aneurysms.

Authors:  Monique Prinssen; Eric L G Verhoeven; Jaap Buth; Philippe W M Cuypers; Marc R H M van Sambeek; Ron Balm; Erik Buskens; Diederick E Grobbee; Jan D Blankensteijn
Journal:  N Engl J Med       Date:  2004-10-14       Impact factor: 91.245

9.  Comparison of endovascular aneurysm repair with open repair in patients with abdominal aortic aneurysm (EVAR trial 1), 30-day operative mortality results: randomised controlled trial.

Authors:  R M Greenhalgh; L C Brown; G P S Kwong; J T Powell; S G Thompson
Journal:  Lancet       Date:  2004 Sep 4-10       Impact factor: 79.321

10.  Diameter of abdominal aortic aneurysm and outcome of endovascular aneurysm repair: does size matter? A report from EUROSTAR.

Authors:  Noud Peppelenbosch; Jacob Buth; Peter L Harris; Corine van Marrewijk; Gerdine Fransen
Journal:  J Vasc Surg       Date:  2004-02       Impact factor: 4.268

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  24 in total

1.  Current Endovascular Management of Abdominal Aortic Aneurysm.

Authors:  April A Grant; Stephen L Chastain; Bruce H Gray
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2.  A one-stage operation for abdominal aortic aneurysm and intraductal papillary mucinous neoplasms of the pancreas: report of a case.

Authors:  Yoshihiko Tsuji; Ikurou Kitano; Katsuhiro Sawada
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3.  Readmission After Liver Resection for Intrahepatic Cholangiocarcinoma: a Multi-Institutional Analysis.

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Journal:  J Gastrointest Surg       Date:  2015-04-23       Impact factor: 3.452

4.  Improving observational study estimates of treatment effects using joint modeling of selection effects and outcomes: the case of AAA repair.

Authors:  A James O'Malley; Philip Cotterill; Marc L Schermerhorn; Bruce E Landon
Journal:  Med Care       Date:  2011-12       Impact factor: 2.983

Review 5.  Open versus endovascular abdominal aortic aneurysm repair in Medicare beneficiaries.

Authors:  Sarah E Deery; Marc L Schermerhorn
Journal:  Surgery       Date:  2017-03-23       Impact factor: 3.982

6.  Developing strategies for predicting and preventing readmissions in vascular surgery.

Authors:  Benjamin S Brooke; Randall R De Martino; Micah Girotti; Justin B Dimick; Philip P Goodney
Journal:  J Vasc Surg       Date:  2012-06-26       Impact factor: 4.268

7.  Early reintervention after open and endovascular abdominal aortic aneurysm repair is associated with high mortality.

Authors:  Sarah E Deery; Thomas F X O'Donnell; Thomas C F Bodewes; Barbara A Dalebout; Alexander B Pothof; Katie E Shean; Jeremy D Darling; Marc L Schermerhorn
Journal:  J Vasc Surg       Date:  2017-09-21       Impact factor: 4.268

8.  Ten-year comparison of all-cause mortality after endovascular or open repair of abdominal aortic aneurysms: a propensity score analysis.

Authors:  Hong-Gi Lee; Daniel G Clair; Kenneth Ouriel
Journal:  World J Surg       Date:  2013-03       Impact factor: 3.352

9.  Causes and implications of readmission after abdominal aortic aneurysm repair.

Authors:  David Yu Greenblatt; Caprice C Greenberg; Amy J H Kind; Jeffrey A Havlena; Matthew W Mell; Matthew T Nelson; Maureen A Smith; K Craig Kent
Journal:  Ann Surg       Date:  2012-10       Impact factor: 12.969

10.  Ten-year results of endovascular abdominal aortic aneurysm repair from a large multicenter registry.

Authors:  Robert W Chang; Philip Goodney; Lue-Yen Tucker; Steven Okuhn; Hong Hua; Ann Rhoades; Nayan Sivamurthy; Bradley Hill
Journal:  J Vasc Surg       Date:  2013-05-14       Impact factor: 4.268

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