Literature DB >> 21028

Effect of metabolic alkalosis on respiratory function in patients with chronic obstructive lung disease.

R Bear, M Goldstein, E Phillipson, M Ho, M Hammeke, R Feldman, S Handelsman, M Halperin.   

Abstract

Eleven instances of a mixed acid-base disorder consisting of chronic respiratory acidosis and metabolic alkalosis were recognized in eight patients with chronic obstructive lung disease and carbon dioxide retention. Correction of the metabolic alkalosis led to substantial improvement in blood gas values and clinical symptoms. Patients with mixed chronic respiratory acidosis and metabolic alkalosis constitute a common subgroup of patients with chronic obstructive lung disease and carbon dioxide retention; these patients benefit from correction of the metabolic alkalosis.

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Year:  1977        PMID: 21028      PMCID: PMC1880127     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  15 in total

1.  THE RESPONSE OF EXTRACELLULAR HYDROGEN ION CONCENTRATION TO GRADED DEGREES OF CHRONIC HYPERCAPNIA: THE PHYSIOLOGIC LIMITS OF THE DEFENSE OF PH.

Authors:  W B SCHWARTZ; N C BRACKETT; J J COHEN
Journal:  J Clin Invest       Date:  1965-02       Impact factor: 14.808

2.  ROLE OF CEREBRAL FLUIDS IN CONTROL OF RESPIRATION AS STUDIED IN UNANESTHETIZED GOATS.

Authors:  J R PAPPENHEIMER; V FENCL; S R HEISEY; D HELD
Journal:  Am J Physiol       Date:  1965-03

3.  Effects of the carbonic anhydrase inhibitor "6063" (diamox) on respiration and electrolyte metabolism of patients with respiratory acidosis.

Authors:  A L L BELL; C N SMITH; E ANDREAE
Journal:  Am J Med       Date:  1955-04       Impact factor: 4.965

4.  The effects of the carbonic anhydrase inhibitor 6063 on electrolytes and acid-base balance in two normal subjects and two patients with respiratory acidosis.

Authors:  J NADELL
Journal:  J Clin Invest       Date:  1953-07       Impact factor: 14.808

Review 5.  Bicarbonate and the regulation of ventilation.

Authors:  H O Heinemann; R M Goldring
Journal:  Am J Med       Date:  1974-09       Impact factor: 4.965

Review 6.  Regulation of cerebrospinal fluid composition with reference to breathing.

Authors:  I Leusen
Journal:  Physiol Rev       Date:  1972-01       Impact factor: 37.312

7.  An in vivo acid-base nomogram for clinical use.

Authors:  G S Arbus
Journal:  Can Med Assoc J       Date:  1973-08-18       Impact factor: 8.262

8.  Severe alveolar hypoventilation in a patient with metabolic alkalosis.

Authors:  P B Oliva
Journal:  Am J Med       Date:  1972-06       Impact factor: 4.965

9.  Respiratory-renal adjustments in chronic hypercapnia in man. Extracellular bicarbonate concentration and the regulation of ventilation.

Authors:  R M Goldring; G M Turino; H O Heinemann
Journal:  Am J Med       Date:  1971-12       Impact factor: 4.965

10.  CSF bicarbonate regulation in respiratory acidosis and alkalosis.

Authors:  J Wichser; H Kazemi
Journal:  J Appl Physiol       Date:  1975-03       Impact factor: 3.531

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  11 in total

1.  [Medical therapy of heart and lung diseases. Effects on the respective other organ].

Authors:  S Möhlenkamp; G Weinreich; T Neumann; T Voshaar; H Teschler
Journal:  Herz       Date:  2014-02       Impact factor: 1.443

2.  A clinical approach to the diagnosis of Acid-base disorders.

Authors:  R A Bear
Journal:  Can Fam Physician       Date:  1986-04       Impact factor: 3.275

3.  Therapeutic use of respiratory stimulants. An overview of newer developments.

Authors:  B M Galko; A S Rebuck
Journal:  Drugs       Date:  1985-12       Impact factor: 9.546

4.  Clinical approach to the diagnosis of acid-base disorders.

Authors:  R A Bear; R F Dyck
Journal:  Can Med Assoc J       Date:  1979-01-20       Impact factor: 8.262

5.  Case in Point: Correction of Dialysis-Induced Metabolic Alkalosis.

Authors:  Assad Mohammedzein; Tarek Naguib
Journal:  Fed Pract       Date:  2021-04

Review 6.  Hemokinins and endokinins.

Authors:  N M Page
Journal:  Cell Mol Life Sci       Date:  2004-07       Impact factor: 9.261

7.  Cardiovascular performance and oxyhemoglobin dissociation after acetazolamide in metabolic alkalosis.

Authors:  P Berthelsen
Journal:  Intensive Care Med       Date:  1982       Impact factor: 17.440

8.  Elevated carbon dioxide tension as a predictor of subsequent adverse events in infants with bronchopulmonary dysplasia.

Authors:  Thomas Kovesi; Adel Abdurahman; Marc Blayney
Journal:  Lung       Date:  2006 Jan-Feb       Impact factor: 3.777

9.  Current perspectives on treatment of hypertensive patients with chronic obstructive pulmonary disease.

Authors:  Dipak Chandy; Wilbert S Aronow; Maciej Banach
Journal:  Integr Blood Press Control       Date:  2013-07-09

10.  Mixed acid-base disorders, hydroelectrolyte imbalance and lactate production in hypercapnic respiratory failure: the role of noninvasive ventilation.

Authors:  Claudio Terzano; Fabio Di Stefano; Vittoria Conti; Marta Di Nicola; Gregorino Paone; Angelo Petroianni; Alberto Ricci
Journal:  PLoS One       Date:  2012-04-23       Impact factor: 3.240

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