Literature DB >> 210062

Receptor regulation and target cell responses: studies in the ovarian luteal cell.

J P Harwood, M Conti, P M Conn, M L Dufau, K J Catt.   

Abstract

Studies of hormone-induced 'desensitization' in the luteinized rat ovary show that changes in receptor number and adenylate cyclase at the cell surface result in an altered biological effect of luteinizing hormone on progesterone production. The sensitivity of these effects to changes in gonadotropin levels suggests that receptor turnover or processing is involved in the normal mechanism of hormone action.

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Year:  1978        PMID： 210062     DOI： 10.1016/0303-7207(78)90001-1

Source DB:  PubMed          Journal:  Mol Cell Endocrinol        ISSN： 0303-7207            Impact factor:   4.102


  9 in total

1.  Desensitization of the beta-adrenoceptor-adenylate cyclase system of immature erythrocytes by in-vivo treatment of rats with isoprenaline.

Authors:  G Wiemer; G Kaiser; J Dietz; M Reinhardt; A Wellstein; D Palm
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1981       Impact factor: 3.000

2.  Regulation of ovarian LH/HCG receptors in pregnant rats.

Authors:  U Müller; T Bauknecht; J W Siebers
Journal:  Arch Gynecol       Date:  1980

3.  Aggregation of luteinizing hormone receptors in granulosa cells: a possible mechanism of desensitization to the hormone.

Authors:  A Amsterdam; A Berkowitz; A Nimrod; F Kohen
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

4.  Regulation of primate testicular luteinizing hormone receptors and steroidogenesis.

Authors:  T F Davies; G D Hodgen; M L Dufau; K J Catt
Journal:  J Clin Invest       Date:  1979-10       Impact factor: 14.808

5.  Desensitization of steroidogenesis in cultured Leydig tumor cells: role of cholesterol.

Authors:  D A Freeman; M Ascoli
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

6.  Secretin and VIP-stimulated adenylate cyclase from rat heart. II. Impairment in spontaneous hypertension.

Authors:  P Chatelain; P Robberecht; P De Neef; J C Camus; D Heuse; J Christophe
Journal:  Pflugers Arch       Date:  1980-12       Impact factor: 3.657

7.  Electron-microscopic and morphometric study of vesiculation in the epithelial cell layer of the toad urinary bladder. Effect of antidiuretic hormone.

Authors:  W L Davis; R G Jones; J Ciumei; J P Knight; D B Goodman
Journal:  Cell Tissue Res       Date:  1982       Impact factor: 5.249

8.  Desensitization to gonadotropins in cultured Leydig tumor cells involves loss of gonadotropin receptors and decreased capacity for steroidogenesis.

Authors:  D A Freeman; M Ascoli
Journal:  Proc Natl Acad Sci U S A       Date:  1981-10       Impact factor: 11.205

9.  Rapid stimulation of pinocytosis in human carcinoma cells A-431 by epidermal growth factor.

Authors:  H T Haigler; J A McKanna; S Cohen
Journal:  J Cell Biol       Date:  1979-10       Impact factor: 10.539
  9 in total

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