Literature DB >> 20980645

Beta-carotene is an important vitamin A source for humans.

Tilman Grune1, Georg Lietz, Andreu Palou, A Catharine Ross, Wilhelm Stahl, Guangweng Tang, David Thurnham, Shi-an Yin, Hans K Biesalski.   

Abstract

Experts in the field of carotenoids met at the Hohenheim consensus conference in July 2009 to elucidate the current status of β-carotene research and to summarize the current knowledge with respect to the chemical properties, physiological function, and intake of β-carotene. The experts discussed 17 questions and reached an agreement formulated in a consensus answer in each case. These consensus answers are based on published valid data, which were carefully reviewed by the individual experts and are justified here by background statements. Ascertaining the impact of β-carotene on the total dietary intake of vitamin A is complicated, because the efficiency of conversion of β-carotene to retinol is not a single ratio and different conversion factors have been used in various surveys and following governmental recommendations within different countries. However, a role of β-carotene in fulfilling the recommended intake for vitamin A is apparent from a variety of studies. Thus, besides elucidating the various functions, distribution, and uptake of β-carotene, the consensus conference placed special emphasis on the provitamin A function of β-carotene and the role of β-carotene in the realization of the required/recommended total vitamin A intake in both developed and developing countries. There was consensus that β-carotene is a safe source of vitamin A and that the provitamin A function of β-carotene contributes to vitamin A intake.

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Year:  2010        PMID: 20980645      PMCID: PMC3139236          DOI: 10.3945/jn.109.119024

Source DB:  PubMed          Journal:  J Nutr        ISSN: 0022-3166            Impact factor:   4.798


  138 in total

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5.  A clinical trial of the effects of oral beta-carotene on the responses of human skin to solar radiation.

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  86 in total

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6.  Role of vitamin A metabolism in IIH: Results from the idiopathic intracranial hypertension treatment trial.

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8.  Effects of cooking methods on the β-carotene levels of selected plant food materials.

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9.  Eat Your Carrots! β-Carotene and Cholesterol Homeostasis.

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10.  Retinoic acid and the transcription factor MafB act together and differentially to regulate aggrecan and matrix metalloproteinase gene expression in neonatal chondrocytes.

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