Literature DB >> 20974188

Adaptation of a novel operant orofacial testing system to characterize both mechanical and thermal pain.

Todd A Nolan1, Jordan Hester, Yvonne Bokrand-Donatelli, Robert M Caudle, John K Neubert.   

Abstract

Mechanical pain sensitivity is characteristic of many orofacial pain conditions; however, few models exist to quantify this pain. Here we evaluated a novel adaptation of our existing operant system to characterize orofacial pain following mechanical and thermal stimuli. We demonstrate that the operant system is able to detect painful and analgesic responses to mechanical stimuli. These findings allow comparison of both mechanical and thermal stimuli using the same outcome measures. Copyright Â
© 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID: 20974188      PMCID: PMC3010421          DOI: 10.1016/j.bbr.2010.10.022

Source DB:  PubMed          Journal:  Behav Brain Res        ISSN: 0166-4328            Impact factor:   3.332


  23 in total

1.  Use of a novel thermal operant behavioral assay for characterization of orofacial pain sensitivity.

Authors:  John K Neubert; Charles G Widmer; Wendi Malphurs; Heather L Rossi; Charles J Vierck; Robert M Caudle
Journal:  Pain       Date:  2005-08       Impact factor: 6.961

2.  The orofacial formalin test in rats: effects of different formalin concentrations.

Authors:  Pierre Clavelou; Radhouane Dallel; Thierry Orliaguet; Alain Woda; Patrick Raboisson
Journal:  Pain       Date:  1995-09       Impact factor: 6.961

3.  Characterization of heat-hyperalgesia in an experimental trigeminal neuropathy in rats.

Authors:  Y Imamura; H Kawamoto; O Nakanishi
Journal:  Exp Brain Res       Date:  1997-08       Impact factor: 1.972

4.  Progressive degradation of serial grooming chains by descending decerebration.

Authors:  K C Berridge
Journal:  Behav Brain Res       Date:  1989-07-01       Impact factor: 3.332

5.  Differentiation between capsaicin-induced allodynia and hyperalgesia using a thermal operant assay.

Authors:  John K Neubert; Heather L Rossi; Wendi Malphurs; Charles J Vierck; Robert M Caudle
Journal:  Behav Brain Res       Date:  2006-05-03       Impact factor: 3.332

6.  Behavioral evidence of trigeminal neuropathic pain following chronic constriction injury to the rat's infraorbital nerve.

Authors:  B P Vos; A M Strassman; R J Maciewicz
Journal:  J Neurosci       Date:  1994-05       Impact factor: 6.167

7.  Pain measurement: an overview.

Authors:  C R Chapman; K L Casey; R Dubner; K M Foley; R H Gracely; A E Reading
Journal:  Pain       Date:  1985-05       Impact factor: 6.961

8.  Local and remote modifications of nociceptive sensitivity during carrageenin-induced inflammation in the rat.

Authors:  V Kayser; G Guilbaud
Journal:  Pain       Date:  1987-01       Impact factor: 6.961

9.  Influence of spinalization on spinal withdrawal reflex responses varies depending on the submodality of the test stimulus and the experimental pathophysiological condition in the rat.

Authors:  T Kauppila; V K Kontinen; A Pertovaara
Journal:  Brain Res       Date:  1998-06-29       Impact factor: 3.252

10.  Characterization of cold sensitivity and thermal preference using an operant orofacial assay.

Authors:  Heather L Rossi; Charles J Vierck; Robert M Caudle; John K Neubert
Journal:  Mol Pain       Date:  2006-12-13       Impact factor: 3.395

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  22 in total

1.  Meal duration as a measure of orofacial nociceptive responses in rodents.

Authors:  Phillip R Kramer; Larry L Bellinger
Journal:  J Vis Exp       Date:  2014-01-10       Impact factor: 1.355

2.  A novel operant-based behavioral assay of mechanical allodynia in the orofacial region of rats.

Authors:  Eric L Rohrs; Heidi E Kloefkorn; Emily H Lakes; Brittany Y Jacobs; John K Neubert; Robert M Caudle; Kyle D Allen
Journal:  J Neurosci Methods       Date:  2015-03-28       Impact factor: 2.390

3.  Phosphorylation of the N-methyl-d-aspartate receptor is increased in the nucleus accumbens during both acute and extended morphine withdrawal.

Authors:  Ethan M Anderson; Turi Reeves; Katherine Kapernaros; John K Neubert; Robert M Caudle
Journal:  J Pharmacol Exp Ther       Date:  2015-09-16       Impact factor: 4.030

4.  Use of the Operant Orofacial Pain Assessment Device (OPAD) to measure changes in nociceptive behavior.

Authors:  Ethan M Anderson; Richard Mills; Todd A Nolan; Alan C Jenkins; Golam Mustafa; Chris Lloyd; Robert M Caudle; John K Neubert
Journal:  J Vis Exp       Date:  2013-06-10       Impact factor: 1.355

5.  Behavioral characteristics of capsaicin mediated cutaneous, myogenic, and arthrogenic orofacial nociception in rats.

Authors:  Eric L Rohrs; John K Neubert; Robert M Caudle; Kyle D Allen
Journal:  Arch Oral Biol       Date:  2018-04-30       Impact factor: 2.633

6.  Assessment of chronic trigeminal neuropathic pain by the orofacial operant test in rats.

Authors:  Myeounghoon Cha; Kevin J Kohan; Xiaozhuo Zuo; Jennifer X Ling; Jianguo G Gu
Journal:  Behav Brain Res       Date:  2012-06-26       Impact factor: 3.332

7.  Effects of diet-induced obesity on motivation and pain behavior in an operant assay.

Authors:  H L Rossi; A K S Luu; S D Kothari; A Kuburas; J K Neubert; R M Caudle; A Recober
Journal:  Neuroscience       Date:  2013-01-16       Impact factor: 3.590

8.  Anti-nociceptive effect of a conjugate of substance P and light chain of botulinum neurotoxin type A.

Authors:  Golam Mustafa; Ethan M Anderson; Yvonne Bokrand-Donatelli; John K Neubert; Robert M Caudle
Journal:  Pain       Date:  2013-08-08       Impact factor: 6.961

Review 9.  Review of preclinical studies on treatment of mucositis and associated pain.

Authors:  C T Viet; P M Corby; A Akinwande; B L Schmidt
Journal:  J Dent Res       Date:  2014-06-18       Impact factor: 6.116

Review 10.  An overview of animal models of pain: disease models and outcome measures.

Authors:  Nicholas S Gregory; Amber L Harris; Caleb R Robinson; Patrick M Dougherty; Perry N Fuchs; Kathleen A Sluka
Journal:  J Pain       Date:  2013-09-12       Impact factor: 5.820

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