BACKGROUND: The epidemiological evidence supporting a causal link between Mediterranean diets and body weight is contrasting. We evaluated the effect of Mediterranean diets on body weight in randomized controlled trials (RCTs) using a meta-analysis. METHODS: We searched English and non-English publications in PubMed, Embase, Scopus, and the Cochrane Central Register of Controlled Trials from inception to January, 2010. Two evaluators independently selected and reviewed eligible studies. Sixteen randomized controlled trials, with 19 arms and 3,436 participants (1,848 assigned to a Mediterranean diet and 1,588 assigned to a control diet) were included. RESULTS: In a random-effects meta-analysis of all 19 arms, the Mediterranean diet group had a significant effect on weight [mean difference between Mediterranean diet and control diet, -1.75 kg; 95% confidence interval (CI), -2.86 to -0.64 kg] and body mass index (mean difference, -0.57 kg/m², -0.93 to -0.21 kg/m²). The effect of Mediterranean diet on body weight was greater in association with energy restriction (mean difference, -3.88 kg, -6.54 to -1.21 kg), increased physical activity (-4.01 kg, -5.79 to -2.23 kg), and follow up longer than 6 months (-2.69 kg, -3.99 to -1.38 kg). No study reported significant weight gain with a Mediterranean diet. CONCLUSIONS: Mediterranean diet may be a useful tool to reduce body weight, especially when the Mediterranean diet is energy-restricted, associated with physical activity, and more than 6 months in length. Mediterranean diet does not cause weight gain, which removes the objection to its relatively high fat content. These results may be useful for helping people to lose weight.
BACKGROUND: The epidemiological evidence supporting a causal link between Mediterranean diets and body weight is contrasting. We evaluated the effect of Mediterranean diets on body weight in randomized controlled trials (RCTs) using a meta-analysis. METHODS: We searched English and non-English publications in PubMed, Embase, Scopus, and the Cochrane Central Register of Controlled Trials from inception to January, 2010. Two evaluators independently selected and reviewed eligible studies. Sixteen randomized controlled trials, with 19 arms and 3,436 participants (1,848 assigned to a Mediterranean diet and 1,588 assigned to a control diet) were included. RESULTS: In a random-effects meta-analysis of all 19 arms, the Mediterranean diet group had a significant effect on weight [mean difference between Mediterranean diet and control diet, -1.75 kg; 95% confidence interval (CI), -2.86 to -0.64 kg] and body mass index (mean difference, -0.57 kg/m², -0.93 to -0.21 kg/m²). The effect of Mediterranean diet on body weight was greater in association with energy restriction (mean difference, -3.88 kg, -6.54 to -1.21 kg), increased physical activity (-4.01 kg, -5.79 to -2.23 kg), and follow up longer than 6 months (-2.69 kg, -3.99 to -1.38 kg). No study reported significant weight gain with a Mediterranean diet. CONCLUSIONS: Mediterranean diet may be a useful tool to reduce body weight, especially when the Mediterranean diet is energy-restricted, associated with physical activity, and more than 6 months in length. Mediterranean diet does not cause weight gain, which removes the objection to its relatively high fat content. These results may be useful for helping people to lose weight.
Authors: Katherine Esposito; Maria Ida Maiorino; Giuseppe Bellastella; Demosthenes B Panagiotakos; Dario Giugliano Journal: Endocrine Date: 2016-07-09 Impact factor: 3.633
Authors: Luigi Barrea; Giuseppe Annunziata; Laura Bordoni; Giovanna Muscogiuri; Annamaria Colao; Silvia Savastano Journal: Int J Obes Suppl Date: 2020-07-20
Authors: Laura Esteban-Gonzalo; Óscar L Veiga; Enrique Regidor; David Martínez; Ascensión Marcos; Maria Elisa Calle Journal: J Immigr Minor Health Date: 2015-04
Authors: Carmen Sayón-Orea; Cristina Razquin; Mónica Bulló; Dolores Corella; Montserrat Fitó; Dora Romaguera; Jesús Vioque; Ángel M Alonso-Gómez; Julia Wärnberg; J Alfredo Martínez; Luís Serra-Majem; Ramón Estruch; Francisco J Tinahones; José Lapetra; Xavier Pintó; Josep A Tur; José López-Miranda; Aurora Bueno-Cavanillas; Miguel Delgado-Rodríguez; Pilar Matía-Martín; Lidia Daimiel; Vicente Martín Sánchez; Josep Vidal; Clotilde Vázquez; Emilio Ros; Miguel Ruiz-Canela; José V Sorlí; Olga Castañer; Miquel Fiol; Eva M Navarrete-Muñoz; Fernando Arós; Enrique Gómez-Gracia; M Angeles Zulet; Almudena Sánchez-Villegas; Rosa Casas; Rosa Bernal-López; José M Santos-Lozano; Emili Corbella; Cristina Bouzas; Ana García-Arellano; Josep Basora; Eva M Asensio; Helmut Schröder; Manuel Moñino; Manoli García de la Hera; Lucas Tojal-Sierra; Estefanía Toledo; Andrés Díaz-López; Albert Goday; Jordi Salas-Salvadó; Miguel A Martínez-González Journal: JAMA Date: 2019-10-15 Impact factor: 56.272