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Literature DB >> 20972498

Drug encapsulation within self-assembled microglobules formed by thermoresponsive supramolecules.

José E Betancourt¹, Chandramouleeswaran Subramani, José L Serrano-Velez, Eduardo Rosa-Molinar, Vincent M Rotello, José M Rivera.

Abstract

An 8-(phenyl)-2'-deoxyguanosine derivative self-assembles in aqueous media into discrete hexadecamers that further self-assemble above 32 °C into microglobules that encapsulate the drug doxorubicin.

Entities: Chemical Disease Gene

Mesh：

Substances：

Year: 2010 PMID： 20972498 PMCID： PMC3021979 DOI： 10.1039/c0cc04063k

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

18 in total

1. Toward self-organization and complex matter.

Authors: Jean-Marie Lehn
Journal: Science Date: 2002-03-29 Impact factor: 47.728

Review 2. Multifunctional nanocarriers.

Authors: Vladimir P Torchilin
Journal: Adv Drug Deliv Rev Date: 2006-09-28 Impact factor: 15.470

3. Solvent-induced high fidelity switching between two discrete supramolecules.

Authors: José E Betancourt; Mariana Martín-Hidalgo; Vladimir Gubala; José M Rivera
Journal: J Am Chem Soc Date: 2009-03-11 Impact factor: 15.419

4. Structure of the first parallel DNA quadruplex-drug complex.

Authors: George R Clark; Patrycja D Pytel; Christopher J Squire; Stephen Neidle
Journal: J Am Chem Soc Date: 2003-04-09 Impact factor: 15.419

5. Incorporation and in vitro release of doxorubicin in thermally sensitive micelles made from poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide)-b-poly(D,L-lactide-co-glycolide) with varying compositions.

Authors: S Q Liu; Y W Tong; Yi-Yan Yang
Journal: Biomaterials Date: 2005-08 Impact factor: 12.479

6. Self-assembled thermo- and pH responsive micelles of poly(10-undecenoic acid-b-N-isopropylacrylamide) for drug delivery.

Authors: Hua Wei; Xian-Zheng Zhang; Han Cheng; Wen-Qin Chen; Si-Xue Cheng; Ren-Xi Zhuo
Journal: J Control Release Date: 2006-09-01 Impact factor: 9.776

7. A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas.

Authors: Cameron C Lee; Elizabeth R Gillies; Megan E Fox; Steven J Guillaudeu; Jean M J Fréchet; Edward E Dy; Francis C Szoka
Journal: Proc Natl Acad Sci U S A Date: 2006-10-30 Impact factor: 11.205

Review 8. Targeted drug delivery by thermally responsive polymers.

Authors: Ashutosh Chilkoti; Matthew R Dreher; Dan E Meyer; Drazen Raucher
Journal: Adv Drug Deliv Rev Date: 2002-09-13 Impact factor: 15.470

9. Tumor-targeting peptide conjugated pH-responsive micelles as a potential drug carrier for cancer therapy.

Authors: Xiang Lan Wu; Jong Ho Kim; Heebeom Koo; Sang Mun Bae; Hyeri Shin; Min Sang Kim; Byung-Heon Lee; Rang-Woon Park; In-San Kim; Kuiwon Choi; Ick Chan Kwon; Kwangmeyung Kim; Doo Sung Lee
Journal: Bioconjug Chem Date: 2010-02-17 Impact factor: 4.774

6. Construction of a cross-layer linked G-octamer via conformational control: a stable G-quadruplex in H-bond competitive solvents.

Authors: Ying He; Yanbin Zhang; Lukasz Wojtas; Novruz G Akhmedov; David Thai; Heng Wang; Xiaopeng Li; Hao Guo; Xiaodong Shi
Journal: Chem Sci Date: 2019-03-06 Impact factor: 9.825

6 in total

Drug encapsulation within self-assembled microglobules formed by thermoresponsive supramolecules.

1. Toward self-organization and complex matter.

Review 2. Multifunctional nanocarriers.

3. Solvent-induced high fidelity switching between two discrete supramolecules.

4. Structure of the first parallel DNA quadruplex-drug complex.

5. Incorporation and in vitro release of doxorubicin in thermally sensitive micelles made from poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide)-b-poly(D,L-lactide-co-glycolide) with varying compositions.

6. Self-assembled thermo- and pH responsive micelles of poly(10-undecenoic acid-b-N-isopropylacrylamide) for drug delivery.

7. A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas.

Review 8. Targeted drug delivery by thermally responsive polymers.

9. Tumor-targeting peptide conjugated pH-responsive micelles as a potential drug carrier for cancer therapy.

10. Walking a supramolecular tightrope: a self-assembled dodecamer from an 8-aryl-2'-deoxyguanosine derivative.

1. Tuning thermoresponsive supramolecular G-quadruplexes.

2. Patchy supramolecules as versatile tools to probe hydrophobicity in nanoglobular systems.

3. Organic Nanoflowers from a Wide Variety of Molecules Templated by a Hierarchical Supramolecular Scaffold.

4. An aquatic host-guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin.

5. Tracking the formation of supramolecular G-quadruplexes via self-assembly enhanced emission.

6. Construction of a cross-layer linked G-octamer via conformational control: a stable G-quadruplex in H-bond competitive solvents.