Literature DB >> 22895684

An aquatic host-guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin.

José M Rivera1, Mariana Martín-Hidalgo, Jean C Rivera-Ríos.   

Abstract

We describe the synthesis of a fluorescent deoxyguanosine derivative that co-assembles (in water) with an unlabeled analogue into a heteromeric supramolecular G-quadruplex, which forms a host-guest complex with doxorubicin as evidenced by FRET experiments.

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Year:  2012        PMID： 22895684      PMCID： PMC3646657          DOI： 10.1039/c2ob25913c

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  16 in total

Review 1.  G-quartets 40 years later: from 5'-GMP to molecular biology and supramolecular chemistry.

Authors:  Jeffery T Davis
Journal:  Angew Chem Int Ed Engl       Date:  2004-01-30       Impact factor: 15.336

2.  Expanding the Hoogsteen edge of 2'-deoxyguanosine: consequences for G-quadruplex formation.

Authors:  Vladimir Gubala; José E Betancourt; José M Rivera
Journal:  Org Lett       Date:  2004-12-09       Impact factor: 6.005

Review 3.  Supramolecular architectures generated by self-assembly of guanosine derivatives.

Authors:  Jeffery T Davis; Gian Piero Spada
Journal:  Chem Soc Rev       Date:  2006-11-07       Impact factor: 54.564

4.  Structure of the first parallel DNA quadruplex-drug complex.

Authors:  George R Clark; Patrycja D Pytel; Christopher J Squire; Stephen Neidle
Journal:  J Am Chem Soc       Date:  2003-04-09       Impact factor: 15.419

5.  Aquatic self-assembly of sixteen subunits into a 39-kDa dendrimer.

Authors:  Luis R Rivera; José E Betancourt; José M Rivera
Journal:  Langmuir       Date:  2010-11-30       Impact factor: 3.882

6.  Nonpolymeric thermosensitive supramolecules.

Authors:  José E Betancourt; José M Rivera
Journal:  J Am Chem Soc       Date:  2009-11-25       Impact factor: 15.419

7.  Analysis and optimization of copper-catalyzed azide-alkyne cycloaddition for bioconjugation.

Authors:  Vu Hong; Stanislav I Presolski; Celia Ma; M G Finn
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

8.  A fluorogenic 1,3-dipolar cycloaddition reaction of 3-azidocoumarins and acetylenes.

Authors:  Krishnamoorthy Sivakumar; Fang Xie; Brandon M Cash; Su Long; Hannah N Barnhill; Qian Wang
Journal:  Org Lett       Date:  2004-11-25       Impact factor: 6.005

9.  Isostructural self-assembly of 2'-deoxyguanosine derivatives in aqueous and organic media.

Authors:  Marilyn García-Arriaga; Gerard Hobley; José M Rivera
Journal:  J Am Chem Soc       Date:  2008-07-22       Impact factor: 15.419

10.  Hexadecameric self-assembled dendrimers built from 2'-deoxyguanosine derivatives.

Authors:  José E Betancourt; José M Rivera
Journal:  Org Lett       Date:  2008-05-02       Impact factor: 6.005
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  5 in total

1.  Tracking the formation of supramolecular G-quadruplexes via self-assembly enhanced emission.

Authors:  Diana Silva-Brenes; Loruhama Delgado; José M Rivera
Journal:  Org Biomol Chem       Date:  2017-01-25       Impact factor: 3.876

2.  Role of Chromatin Damage and Chromatin Trapping of FACT in Mediating the Anticancer Cytotoxicity of DNA-Binding Small-Molecule Drugs.

Authors:  Elimelech Nesher; Alfiya Safina; Ieman Aljahdali; Scott Portwood; Eunice S Wang; Igor Koman; Jianmin Wang; Katerina V Gurova
Journal:  Cancer Res       Date:  2018-01-16       Impact factor: 12.701

3.  A photoresponsive supramolecular G-quadruplex.

Authors:  José M Rivera; Diana Silva-Brenes
Journal:  Org Lett       Date:  2013-05-03       Impact factor: 6.005

4.  Understanding complex supramolecular landscapes: non-covalent macrocyclization equilibria examined by fluorescence resonance energy transfer.

Authors:  María J Mayoral; David Serrano-Molina; Jorge Camacho-García; Eva Magdalena-Estirado; Marina Blanco-Lomas; Elham Fadaei; David González-Rodríguez
Journal:  Chem Sci       Date:  2018-08-20       Impact factor: 9.825

5.  Construction of a cross-layer linked G-octamer via conformational control: a stable G-quadruplex in H-bond competitive solvents.

Authors:  Ying He; Yanbin Zhang; Lukasz Wojtas; Novruz G Akhmedov; David Thai; Heng Wang; Xiaopeng Li; Hao Guo; Xiaodong Shi
Journal:  Chem Sci       Date:  2019-03-06       Impact factor: 9.825
  5 in total

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