Literature DB >> 20946240

Etiology of chronic leg ulcers in 31,619 patients in Germany analyzed by an expert survey.

Andreas Körber1, Joachim Klode, Samy Al-Benna, Caroline Wax, Dirk Schadendorf, Lars Steinstraesser, Joachim Dissemond.   

Abstract

BACKGROUND: The etiology of chronic leg ulcers is heterogenous and they exhibit quite different healing rates depending on the underlying cause. Although the prevalence and incidence of chronic leg ulcers appear to be increasing, data on these patients in Germany are lacking. PATIENTS AND METHODS: Altogether 100 German wound care professionals were asked to complete a questionnaire regarding the diagnosis and etiology of their patients with chronic leg ulcers.
RESULTS: We received the data on 31,619 patients. In these patients, venous insufficiency was the dominating causative factor in 47.6 % and arterial insufficiency in 14.5 %, 17.6 % of ulcers were due to combined arterial and venous insufficiency. Rarer causes included vasculitis (5.1 %), exogenous factors (3.8 %), pyoderma gangrenosum (3.0 %), infection (1.4 %), neoplasia (1.1 %), calciphylaxis (1.1 %) and drug-induced (1.1 %). The used diagnostic methods used varied widely between the medical and surgical specialties.
CONCLUSIONS: Even though the results of our study cannot claim to be a representative overview, they demonstrate clearly that next to known etiologies, e. g. chronic venous insufficiency or peripheral arterial insufficiency, which are relevant in 79.7 % of all patients a multitude of other causes exist, which are responsible in 20.3 % of all patients for the development of chronic leg ulcers.
© The Authors • Journal compilation © Blackwell Verlag GmbH, Berlin.

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Year:  2010        PMID: 20946240     DOI: 10.1111/j.1610-0387.2010.07535.x

Source DB:  PubMed          Journal:  J Dtsch Dermatol Ges        ISSN: 1610-0379            Impact factor:   5.584


  39 in total

1.  Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial.

Authors:  Philippe Humbert; Jacek Mikosinki; Hakima Benchikhi; François-André Allaert
Journal:  Int Wound J       Date:  2012-03-08       Impact factor: 3.315

2.  [Wound healing in the elderly].

Authors:  S A Eming; M Wlaschek; K Scharffetter-Kochanek
Journal:  Hautarzt       Date:  2016-02       Impact factor: 0.751

3.  The financial and quality-of-life cost to patients living with a chronic wound in the community.

Authors:  Suzanne Kapp; Nick Santamaria
Journal:  Int Wound J       Date:  2017-06-20       Impact factor: 3.315

Review 4.  [Chronic leg ulcers].

Authors:  J Dissemond
Journal:  Hautarzt       Date:  2017-08       Impact factor: 0.751

5.  [Quality of self-applied compression bandages in patients with chronic venous ulcers : Results of a prospective clinical study].

Authors:  M Stoffels-Weindorf; I Stoffels; F Jockenhöfer; J Dissemond
Journal:  Hautarzt       Date:  2018-04       Impact factor: 0.751

6.  Pyoderma gangrenosum associated with chronic polyarthritis.

Authors:  Norman-Philipp Hoff; Peter Arne Gerber
Journal:  CMAJ       Date:  2011-08-22       Impact factor: 8.262

7.  Oxygenation Status in Chronic Leg Ulcer After Topical Hemoglobin Application May Act as a Surrogate Marker to Find the Best Treatment Strategy and to Avoid Ineffective Conservative Long-term Therapy.

Authors:  Maximilian Petri; Ingo Stoffels; Klaus Griewank; Jithin Jose; Peter Engels; Andrea Schulz; Harald Pötzschke; Philipp Jansen; Dirk Schadendorf; Joachim Dissemond; Joachim Klode
Journal:  Mol Imaging Biol       Date:  2018-02       Impact factor: 3.488

8.  [Panton-Valentine leukocidin in patients with chronic wounds. Results from a clinical investigation in 100 patients].

Authors:  C Hammer; P-M Rath; J Steinmann; M Stoffels-Weindorf; J Klode; J Dissemond
Journal:  Hautarzt       Date:  2014-02       Impact factor: 0.751

9.  Aetiology, comorbidities and cofactors of chronic leg ulcers: retrospective evaluation of 1 000 patients from 10 specialised dermatological wound care centers in Germany.

Authors:  Finja Jockenhöfer; Harald Gollnick; Katharina Herberger; Georg Isbary; Regina Renner; Markus Stücker; Eva Valesky; Uwe Wollina; Michael Weichenthal; Sigrid Karrer; Bernhard Kuepper; Alexander Roesch; Joachim Dissemond
Journal:  Int Wound J       Date:  2014-12-05       Impact factor: 3.315

10.  Impact of Gram-negative bacteria on the treatment of venous leg ulcers.

Authors:  Wibke L Engelberg; Martin Dörler; Markus Stücker; Stefanie Reich-Schupke
Journal:  Int Wound J       Date:  2018-08-05       Impact factor: 3.315

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