Literature DB >> 2094230

Management of autonomic dysfunction in severe tetanus: the use of magnesium sulphate and clonidine.

D N Sutton1, M R Tremlett, T E Woodcock, M S Nielsen.   

Abstract

The treatment of severe tetanus with autonomic dysfunction is discussed, with emphasis on the use of magnesium sulphate. An exemplary case is reported, describing the inadequate response to magnesium, but the previously unreported and successful use of clonidine to control sympathetic overactivity. The properties of clonidine are reviewed. Clonidine is felt to be a logical and appropriate drug for the treatment of autonomic dysfunction in severe tetanus.

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Year:  1990        PMID： 2094230     DOI： 10.1007/bf02575297

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN： 0342-4642            Impact factor:   17.440


  14 in total

Review 1.  Tetanus.

Authors:  J J Farrar; L M Yen; T Cook; N Fairweather; N Binh; J Parry; C M Parry
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-09       Impact factor: 10.154

Review 2.  [Treatment strategies for tetanus].

Authors:  T Duning; W R Schäbitz
Journal:  Nervenarzt       Date:  2007-02       Impact factor: 1.214

3.  Autonomous dysfunction in severe tetanus.

Authors:  F E Udwadia; Z F Udwadia; A Lall
Journal:  Intensive Care Med       Date:  1990       Impact factor: 17.440

4.  Management of tetanus: a review of 18 cases.

Authors:  T P Bleck
Journal:  J R Soc Med       Date:  1994-09       Impact factor: 5.344

5.  Management of tetanus.

Authors:  T P Bleck
Journal:  J R Soc Med       Date:  1994-11       Impact factor: 5.344

Review 6.  Tetanus in Ethiopia: unveiling the blight of an entirely vaccine-preventable disease.

Authors:  Yohannes Woubishet Woldeamanuel
Journal:  Curr Neurol Neurosci Rep       Date:  2012-12       Impact factor: 5.081

Review 7.  Critical care pharmacotherapy. A review.

Authors:  M Tryba; P J Kulka
Journal:  Drugs       Date:  1993-03       Impact factor: 9.546

8.  Prolonged high-dose intravenous magnesium therapy for severe tetanus in the intensive care unit: a case series.

Authors:  Menelaos Karanikolas; Dimitrios Velissaris; Markos Marangos; Vassilios Karamouzos; Fotini Fligou; Kriton S Filos
Journal:  J Med Case Rep       Date:  2010-03-31

9.  Use of intrathecal and intravenous clonidine in a case of severe tetanus with acute renal failure.

Authors:  Alok Kumar; Raktima Anand; Anita Rahal; Sandhya Od
Journal:  Indian J Anaesth       Date:  2009-04

10.  Respiratory, metabolic and hemodynamic effects of clonidine in ventilated patients presenting with withdrawal syndrome.

Authors:  Domniki Liatsi; Basilis Tsapas; Smaro Pampori; Matthew Tsagourias; Ioannis Pneumatikos; Dimitrios Matamis
Journal:  Intensive Care Med       Date:  2008-08-16       Impact factor: 17.440
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