Literature DB >> 22996275

Tetanus in Ethiopia: unveiling the blight of an entirely vaccine-preventable disease.

Yohannes Woubishet Woldeamanuel1.   

Abstract

Today, tetanus exacts its toll only in resource-poor countries like Ethiopia. Agrarian rural life with limited vaccine typifies tetanus risk in Ethiopia where current tetanus control trends on expanding infant immunization and eliminating highly prevalent maternal and neonatal tetanus (MNT). Protection by infant tetanus immunization primers disappears within an average of 3 years, if not followed by boosters. Second-year of life, school-based, and universal 10-yearly tetanus immunizations need to be supplemented. Facility-based reviews in Ethiopia reveal a continued burden of tetanus at tertiary-level hospitals where ICU care is suboptimal. Quality of medical care for tetanus is low - reflected by high case-fatality-rates. Opportunities at primary-health-care-units (antenatal-care, family planning, abortion, wound-care, tetanus-survivors) need to be fully-utilized to expand tetanus immunization. Prompt wound-care with post-exposure prophylaxis and proper footwear must be promoted. Standard ICU care needs to exist. Realization of cold-chain-flexible, needle-less and mono-dose vaccine programs allow avoiding boosters, vaccine-refrigeration, and improve compliance.

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Year:  2012        PMID: 22996275     DOI: 10.1007/s11910-012-0314-3

Source DB:  PubMed          Journal:  Curr Neurol Neurosci Rep        ISSN: 1528-4042            Impact factor:   5.081


  75 in total

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Journal:  Lancet       Date:  2006-04-08       Impact factor: 79.321

2.  Case-fatality of adult tetanus at Jimma University Teaching Hospital, Southwest Ethiopia.

Authors:  A Amare; A Yami
Journal:  Afr Health Sci       Date:  2011-03       Impact factor: 0.927

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Journal:  Trans R Soc Trop Med Hyg       Date:  1970       Impact factor: 2.184

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Journal:  JAMA       Date:  1986-03-07       Impact factor: 56.272

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6.  Placental transfer and maternally acquired neonatal IgG immunity in human immunodeficiency virus infection.

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Journal:  J Infect Dis       Date:  1996-05       Impact factor: 5.226

7.  Protecting adolescent girls against tetanus.

Authors:  L Brabin; J Kemp; S M Maxwell; J Ikimalo; O K Obunge; N D Briggs
Journal:  BMJ       Date:  1995-07-08

8.  A house-to-house survey of neonatal tetanus in urban and rural areas in the Gondar region, Ethiopia.

Authors:  M Maru; A Getahun; S Hosana
Journal:  Trop Geogr Med       Date:  1988-07

9.  The influence of malaria and gestation on the immune response to one and two doses of adsorbed tetanus toxoid in pregnancy.

Authors:  B J Brabin; J Nagel; A M Hagenaars; E Ruitenberg; A M van Tilborgh
Journal:  Bull World Health Organ       Date:  1984       Impact factor: 9.408

10.  Predictors of defaulting from completion of child immunization in south Ethiopia, May 2008: a case control study.

Authors:  Henoke Tadesse; Amare Deribew; Mirkuzie Woldie
Journal:  BMC Public Health       Date:  2009-05-22       Impact factor: 3.295

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  4 in total

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Authors:  Awoke Derbie; Anteneh Amdu; Amanuel Alamneh; Amare Tadege; Amelwork Solomon; Bihanu Elfu; Daniel Mekonnen; Yinebeb Mezgebu; Seble Worku; Fantahun Biadglegne
Journal:  Springerplus       Date:  2016-06-27

2.  Clinical Profile and Outcome of Pediatrics Tetanus: The Experience of a Tertiary Hospital in Ethiopia.

Authors:  Henok Tadele
Journal:  Ethiop J Health Sci       Date:  2017-09

3.  An unusual complication of the traditional treatment of a closed fracture - generalized tetanus: a case report.

Authors:  Landry W Tchuenkam; Emmanuel K Ndame; Marc L Guifo; Celestin Danwang; Ginette C Kalla; Arthur Essomba
Journal:  J Med Case Rep       Date:  2017-10-24

4.  A Novel High-Potency Tetanus Vaccine.

Authors:  Amanda Przedpelski; William H Tepp; Sabine Pellett; Eric A Johnson; Joseph T Barbieri
Journal:  mBio       Date:  2020-08-11       Impact factor: 7.867

  4 in total

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