Literature DB >> 20940728

Dynamics of regional distribution of ischemic lesions in middle cerebral artery trunk occlusion relates to collateral circulation.

Bastian Cheng1, Amir Golsari, Jens Fiehler, Michael Rosenkranz, Christian Gerloff, Götz Thomalla.   

Abstract

We describe the regional distribution of acute perfusion, diffusion, and final infarct lesions in middle cerebral artery (MCA) trunk occlusion. A total of 31 patients with acute ischemic stroke and MCA trunk occlusion were studied by multiparametric magnetic resonance imaging. Probabilistic maps of lesion distribution were generated. The probability of initial and final infarcts was highest in the central MCA region with decreasing probability toward the periphery where the probability of the tissue at risk of infarction to be saved was highest. The probability of brain regions being involved in acute diffusion lesions and evolving into or escaping from the final infarct relates to the anatomy of arterial blood supply.

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Year:  2010        PMID： 20940728      PMCID： PMC3049469          DOI： 10.1038/jcbfm.2010.185

Source DB:  PubMed          Journal:  J Cereb Blood Flow Metab        ISSN： 0271-678X            Impact factor:   6.200


  15 in total

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Review 2.  Collateral circulation.

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