Literature DB >> 20937944

Beclin 1 complex in autophagy and Alzheimer disease.

Philipp A Jaeger1, Tony Wyss-Coray.   

Abstract

Beclin 1 is a protein involved in the regulation of autophagy and has been shown to be reduced in patients with Alzheimer disease. This review summarizes the current research data that link disturbances in autophagy, a cellular degradation and maintenance pathway, to the development of Alzheimer disease and related neurodegenerative diseases. It also provides a brief overview of the existing pharmacological interventions available to modulate autophagy activity in mammalian cells.

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Year:  2010        PMID： 20937944     DOI： 10.1001/archneurol.2010.258

Source DB:  PubMed          Journal:  Arch Neurol        ISSN： 0003-9942


  36 in total

Review 1.  MicroRNAs in autophagy and their emerging roles in crosstalk with apoptosis.

Authors:  Jianzhen Xu; Yanfei Wang; Xiaorong Tan; Hongjuan Jing
Journal:  Autophagy       Date:  2012-03-23       Impact factor: 16.016

2.  CD2-associated protein (CD2AP) overexpression accelerates amyloid precursor protein (APP) transfer from early endosomes to the lysosomal degradation pathway.

Authors:  Kotaro Furusawa; Toshiyuki Takasugi; Yung-Wen Chiu; Yukiko Hori; Taisuke Tomita; Mitsunori Fukuda; Shin-Ichi Hisanaga
Journal:  J Biol Chem       Date:  2019-05-28       Impact factor: 5.157

Review 3.  Cell death pathways and autophagy in the central nervous system and its involvement in neurodegeneration, immunity and central nervous system infection: to die or not to die--that is the question.

Authors:  A Rosello; G Warnes; U-C Meier
Journal:  Clin Exp Immunol       Date:  2012-04       Impact factor: 4.330

Review 4.  Mechanism and Regulation of Autophagy and Its Role in Neuronal Diseases.

Authors:  Zhiping Hu; Binbin Yang; Xiaoye Mo; Han Xiao
Journal:  Mol Neurobiol       Date:  2014-10-15       Impact factor: 5.590

5.  Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system.

Authors:  Etienne Morel; Zeina Chamoun; Zofia M Lasiecka; Robin B Chan; Rebecca L Williamson; Christopher Vetanovetz; Claudia Dall'Armi; Sabrina Simoes; Kimberly S Point Du Jour; Brian D McCabe; Scott A Small; Gilbert Di Paolo
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

Review 6.  Autophagy in dementias.

Authors:  Christine Lund Kragh; Kiren Ubhi; Tony Wyss-Coray; Tony Wyss-Corey; Eliezer Masliah
Journal:  Brain Pathol       Date:  2012-01       Impact factor: 6.508

7.  Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis.

Authors:  Michela Guglielmotto; Debora Monteleone; Antonio Piras; Valeria Valsecchi; Marta Tropiano; Stefania Ariano; Michele Fornaro; Alessandro Vercelli; Julien Puyal; Ottavio Arancio; Massimo Tabaton; Elena Tamagno
Journal:  Autophagy       Date:  2014-08-12       Impact factor: 16.016

Review 8.  Pathogenesis of age-related HIV neurodegeneration.

Authors:  Miroslaw Mack Mackiewicz; Cassia Overk; Cristian L Achim; Eliezer Masliah
Journal:  J Neurovirol       Date:  2019-02-21       Impact factor: 2.643

9.  Increased expression of Beclin-1-dependent autophagy protects against beta-amyloid-induced cell injury in PC12 cells [corrected].

Authors:  Zhongfeng Xue; Sheng Zhang; Liping Huang; Yuping He; Ruoming Fang; Yongqi Fang
Journal:  J Mol Neurosci       Date:  2013-02-19       Impact factor: 3.444

10.  Anesthetic preconditioning inhibits isoflurane-mediated apoptosis in the developing rat brain.

Authors:  Jun Peng; Julie K Drobish; Ge Liang; Zhen Wu; Chunxia Liu; Donald J Joseph; Hossam Abdou; Maryellen F Eckenhoff; Huafeng Wei
Journal:  Anesth Analg       Date:  2014-10       Impact factor: 5.108
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