Literature DB >> 20929354

A 2009 varicella outbreak in a Connecticut residential facility for adults with intellectual disability.

Jessica Leung1, Kathy Kudish, Chengbin Wang, Latetia Moore, Paul Gacek, Kay Radford, Adriana Lopez, Lynn Sosa, D Scott Schmid, Matthew Cartter, Stephanie Bialek.   

Abstract

We investigated a varicella outbreak in a residential facility for adults with intellectual disabilities. A case of varicella was defined as a generalized maculopapular rash that developed in a facility resident or employee. Immunoglobulin M testing was conducted on serologic samples, and polymerase chain reaction testing was performed on environmental and skin lesion samples. Eleven cases were identified among 70 residents and 2 among ∼145 staff. An unrecognized case of herpes zoster was the likely source. Case patients first entered any residential facility at a younger age than non-case residents (9.5 vs 15.0 years; P < .01). Varicella zoster virus DNA was detected 2 months after the outbreak in environmental samples obtained from case patients' residences. This outbreak exemplifies the potential for at-risk pockets of varicella-susceptible adults, especially among those who have lived in residential facilities from a young age. Evidence of immunity should be verified for all adults and healthcare staff in similar residential settings.

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Year:  2010        PMID: 20929354     DOI: 10.1086/656773

Source DB:  PubMed          Journal:  J Infect Dis        ISSN: 0022-1899            Impact factor:   5.226


  5 in total

1.  Comparison of surface sampling methods for virus recovery from fomites.

Authors:  Timothy R Julian; Francisco J Tamayo; James O Leckie; Alexandria B Boehm
Journal:  Appl Environ Microbiol       Date:  2011-08-05       Impact factor: 4.792

2.  Varicella Vaccine Effectiveness in Preventing Community Transmission in the 2-Dose Era.

Authors:  Dana Perella; Chengbin Wang; Rachel Civen; Kendra Viner; Karen Kuguru; Irini Daskalaki; D Scott Schmid; Adriana S Lopez; Hung Fu Tseng; E Claire Newbern; Laurene Mascola; Stephanie R Bialek
Journal:  Pediatrics       Date:  2016-03-14       Impact factor: 7.124

3.  Challenges with controlling varicella in prison settings: experience of California, 2010 to 2011.

Authors:  Jessica Leung; Adriana S Lopez; Elena Tootell; Nikki Baumrind; Janet Mohle-Boetani; Bruce Leistikow; Kathleen H Harriman; Christopher P Preas; Giorgio Cosentino; Stephanie R Bialek; Mona Marin
Journal:  J Correct Health Care       Date:  2014-09-07

4.  Varicella immunization requirements for US colleges: 2014-2015 academic year.

Authors:  Jessica Leung; Mona Marin; Victor Leino; Susan Even; Stephanie R Bialek
Journal:  J Am Coll Health       Date:  2016-01-30

5.  Containment of varicella outbreak in intensive care unit of a tertiary level hospital.

Authors:  Raman Sharma; Kapil Goyal; Nidhi Bhatia; Vikas Rana; Mini P Singh; Ashish Bhalla; Gurpreet Singh; Ashok Kumar; Kajal Jain
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2021-07-15
  5 in total

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