Literature DB >> 20923500

Targeting metabolic syndrome: candidate natural agents.

Xuan Xia1, Jianping Weng.   

Abstract

Following on from impressive economic development and urbanization, China is currently experiencing a high prevalence of metabolic syndrome. Patients with metabolic syndrome suffer from the "The Deadly Quartet" of hyperglycemia, hypertriglyceridemia, hypertension, and central (or upper body) obesity. Current treatment strategies directed towards metabolic syndrome tend to be limited to just one of these four conditions, so developing novel drugs to target multiple metabolic abnormalities could be preferable to current approaches. New insights suggest benefits of natural agents as treatments for metabolic syndrome. Herein, we review the evidence for using nine such agents developed on the basis of traditional medicine or herbal preparations.
© 2010 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Blackwell Publishing Asia Pty Ltd.

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Year:  2010        PMID: 20923500     DOI: 10.1111/j.1753-0407.2010.00090.x

Source DB:  PubMed          Journal:  J Diabetes        ISSN: 1753-0407            Impact factor:   4.006


  11 in total

1.  Metabolites as novel biomarkers for childhood obesity-related traits in Mexican-American children.

Authors:  V S Farook; L Reddivari; G Chittoor; S Puppala; R Arya; S P Fowler; K J Hunt; J E Curran; A G Comuzzie; D M Lehman; C P Jenkinson; J L Lynch; R A DeFronzo; J Blangero; D E Hale; R Duggirala; J Vanamala
Journal:  Pediatr Obes       Date:  2014-11-18       Impact factor: 4.000

Review 2.  Pathobiological mechanisms underlying metabolic syndrome (MetS) in chronic obstructive pulmonary disease (COPD): clinical significance and therapeutic strategies.

Authors:  Stanley M H Chan; Stavros Selemidis; Steven Bozinovski; Ross Vlahos
Journal:  Pharmacol Ther       Date:  2019-02-26       Impact factor: 12.310

3.  Chlorogenic acid improves anti-lipogenic activity of metformin by positive regulating of AMPK signaling in HepG2 cells.

Authors:  Fatemeh Namvarjah; Hajar Shokri-Afra; Hemen Moradi-Sardareh; Reyhaneh Babaei Khorzoughi; Parvin Pasalar; Ghodratollah Panahi; Reza Meshkani
Journal:  Cell Biochem Biophys       Date:  2022-06-15       Impact factor: 2.989

Review 4.  Cardiac dysfunction and oxidative stress in the metabolic syndrome: an update on antioxidant therapies.

Authors:  Olesya Ilkun; Sihem Boudina
Journal:  Curr Pharm Des       Date:  2013       Impact factor: 3.116

5.  Genistein: A Novel Anthocyanin Synthesis Promoter that Directly Regulates Biosynthetic Genes in Red Cabbage in a Light-Dependent Way.

Authors:  Na Zhang; Yan Qi; Hai-Jun Zhang; Xiaoyun Wang; Hongfei Li; Yantong Shi; Yang-Dong Guo
Journal:  Front Plant Sci       Date:  2016-12-01       Impact factor: 5.753

6.  The effects of trans-resveratrol on insulin resistance, inflammation, and microbiota in men with the metabolic syndrome: A pilot randomized, placebo-controlled clinical trial.

Authors:  Jeanne M Walker; Patricia Eckardt; Jose O Aleman; Joel Correa da Rosa; Yupu Liang; Tadasu Iizumi; Stephane Etheve; Martin J Blaser; Jan L Breslow; Peter R Holt
Journal:  J Clin Transl Res       Date:  2018-12-07

7.  Dietary isoflavone intake, urinary isoflavone level, and their relationship with metabolic syndrome diagnostic components in korean postmenopausal women.

Authors:  Mi Hyun Kim; Yun Jung Bae
Journal:  Clin Nutr Res       Date:  2013-01-29

8.  Development of a Novel Anti-Obesity Compound with Inhibiting Properties on the Lipid Accumulation in 3T3-L1 Adipocytes

Authors:  Moloud Payab; Shirin Hasani-Ranjbar; Maryam Baeeri; Mahban Rahimifard; Babak Arjmand; Hamed Haghi-Aminjan; Mohammad Abdollahi; Bagher Larijani
Journal:  Iran Biomed J       Date:  2019-11-30

9.  Antihyperglycemic and Antilipidemic Effects of the Ethanol Extract Mixture of Ligularia fischeri and Momordica charantia in Type II Diabetes-Mimicking Mice.

Authors:  Hyun Jin Baek; Yong Joon Jeong; Jeong Eun Kwon; Jong Sung Ra; Sung Ryul Lee; Se Chan Kang
Journal:  Evid Based Complement Alternat Med       Date:  2018-10-02       Impact factor: 2.629

10.  Beneficial Effects of an Aged Black Garlic Extract in the Metabolic and Vascular Alterations Induced by a High Fat/Sucrose Diet in Male Rats.

Authors:  Sara Amor; Daniel González-Hedström; Beatriz Martín-Carro; Antonio Manuel Inarejos-García; Paula Almodóvar; Marin Prodanov; Angel Luis García-Villalón; Miriam Granado
Journal:  Nutrients       Date:  2019-01-12       Impact factor: 5.717

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