Literature DB >> 20922231

Novel interstrand communication systems within DNA duplexes based on 1-, 2- and 4-(phenylethynyl)pyrenes attached to 2'-amino-LNA: high-affinity hybridization and fluorescence sensing.

Irina V Astakhova1, Dorthe Lindegaard, Vladimir A Korshun, Jesper Wengel.   

Abstract

Functionalisation of 2'-amino-LNA oligonucleotides with 1-, 2- and 4-(phenylethynyl)pyrene fluorophores via a carbonyl linker (PEPyc) resulted in efficient interstrand communication systems in nucleic acid duplexes, providing effective tools for stabilization of nanostructures and fluorescence monitoring of DNA self-assembly.

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Year:  2010        PMID: 20922231     DOI: 10.1039/c0cc03026k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  8 in total

Review 1.  Pyrene-functionalized oligonucleotides and locked nucleic acids (LNAs): tools for fundamental research, diagnostics, and nanotechnology.

Authors:  Michael E Østergaard; Patrick J Hrdlicka
Journal:  Chem Soc Rev       Date:  2011-04-13       Impact factor: 54.564

2.  Synthesis and biological evaluation of 2',4'- and 3',4'-bridged nucleoside analogues.

Authors:  K C Nicolaou; Shelby P Ellery; Fatima Rivas; Karen Saye; Eric Rogers; Tyler J Workinger; Mark Schallenberger; Rommel Tawatao; Ana Montero; Ann Hessell; Floyd Romesberg; Dennis Carson; Dennis Burton
Journal:  Bioorg Med Chem       Date:  2011-07-23       Impact factor: 3.641

3.  DNA strands with alternating incorporations of LNA and 2'-O-(pyren-1-yl)methyluridine: SNP-discriminating RNA detection probes.

Authors:  Saswata Karmakar; Patrick J Hrdlicka
Journal:  Chem Sci       Date:  2013-09-01       Impact factor: 9.825

4.  Identification and characterization of second-generation invader locked nucleic acids (LNAs) for mixed-sequence recognition of double-stranded DNA.

Authors:  Sujay P Sau; Andreas S Madsen; Peter Podbevsek; Nicolai K Andersen; T Santhosh Kumar; Sanne Andersen; Rie L Rathje; Brooke A Anderson; Dale C Guenther; Saswata Karmakar; Pawan Kumar; Janez Plavec; Jesper Wengel; Patrick J Hrdlicka
Journal:  J Org Chem       Date:  2013-09-25       Impact factor: 4.354

Review 5.  Recent Advances in Nucleic Acid Targeting Probes and Supramolecular Constructs Based on Pyrene-Modified Oligonucleotides.

Authors:  Olga A Krasheninina; Darya S Novopashina; Evgeny K Apartsin; Alya G Venyaminova
Journal:  Molecules       Date:  2017-11-30       Impact factor: 4.411

6.  Synthesis, Photophysical and Electronic Properties of New Red-to-NIR Emitting Donor-Acceptor Pyrene Derivatives.

Authors:  Julia Merz; Maximilian Dietz; Yvonne Vonhausen; Frederik Wöber; Alexandra Friedrich; Daniel Sieh; Ivo Krummenacher; Holger Braunschweig; Michael Moos; Marco Holzapfel; Christoph Lambert; Todd B Marder
Journal:  Chemistry       Date:  2019-11-19       Impact factor: 5.236

7.  Methyl Viologens of Bis-(4'-Pyridylethynyl)Arenes - Structures, Photophysical and Electrochemical Studies, and their Potential Application in Biology.

Authors:  Goutam Kumar Kole; Marta Košćak; Anissa Amar; Dragomira Majhen; Ksenija Božinović; Zlatko Brkljaca; Matthias Ferger; Evripidis Michail; Sabine Lorenzen; Alexandra Friedrich; Ivo Krummenacher; Michael Moos; Holger Braunschweig; Abdou Boucekkine; Christoph Lambert; Jean-François Halet; Ivo Piantanida; Klaus Müller-Buschbaum; Todd B Marder
Journal:  Chemistry       Date:  2022-05-30       Impact factor: 5.020

8.  Synthesis and biophysical properties of C5-functionalized LNA (locked nucleic acid).

Authors:  Pawan Kumar; Michael E Østergaard; Bharat Baral; Brooke A Anderson; Dale C Guenther; Mamta Kaura; Daniel J Raible; Pawan K Sharma; Patrick J Hrdlicka
Journal:  J Org Chem       Date:  2014-05-13       Impact factor: 4.354

  8 in total

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