Literature DB >> 20921864

Persistent insomnia in chronic hypnotic users presenting to a sleep medical center: a retrospective chart review of 137 consecutive patients.

Barry Krakow1, Victor A Ulibarri, Eddie Romero.   

Abstract

Chronic insomnia patients may fail pharmacotherapy. We reviewed charts on 137 chronic insomnia patients new to our sleep medical center who reported persisting insomnia despite long-term usage of pharmacotherapy. We examined 4 areas: (1) patient views on encounters with prescribing physicians; (2) self-reported medication efficacy; (3) treatment-seeking goals; and (4) completion of a sleep medicine workup. Insomnia chronicity averaged 13 years; use of prescription medication for sleep averaged 3.81 years. Encounters with prescribing physicians yielded few options beyond drugs. Drug efficacy was not optimal for most of these patients. Sleeping better or drug-free were their chief goals. Subjective and objective sleep measures confirmed moderately severe residual insomnia as well as fair to poor waking impairment and quality of life. Sleep workup revealed high rates of maladaptive behavioral influences (96%), psychiatric complaints (89%), and obstructive sleep apnea (71%). In chronic insomnia patients who failed pharmacotherapy, comorbid mental and physical factors indicated a sleep disturbance complexity unlikely to respond fully to medication.

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Year:  2010        PMID: 20921864     DOI: 10.1097/NMD.0b013e3181f4aca1

Source DB:  PubMed          Journal:  J Nerv Ment Dis        ISSN: 0022-3018            Impact factor:   2.254


  16 in total

1.  High dosage of hypnotics predicts subsequent sleep-related breathing disorders and is associated with worse outcomes for depression.

Authors:  Cheng-Ta Li; Ya-Mei Bai; Ying-Chiao Lee; Wei-Chung Mao; Mu-Hong Chen; Pei-Chi Tu; Ying-Sheue Chen; Tzeng-Ji Chen; Wen-Hang Chang; Tung-Ping Su
Journal:  Sleep       Date:  2014-04-01       Impact factor: 5.849

Review 2.  Comorbid insomnia in sleep-related breathing disorders: an under-recognized association.

Authors:  Suhaila E Al-Jawder; Ahmed S Bahammam
Journal:  Sleep Breath       Date:  2011-03-29       Impact factor: 2.816

3.  Sleep-wake time perception varies by direct or indirect query.

Authors:  Y Alameddine; J M Ellenbogen; M T Bianchi
Journal:  J Clin Sleep Med       Date:  2015-01-15       Impact factor: 4.062

4.  Prevalence of sleep breathing complaints reported by treatment-seeking chronic insomnia disorder patients on presentation to a sleep medical center: a preliminary report.

Authors:  Barry Krakow; Victor A Ulibarri
Journal:  Sleep Breath       Date:  2012-04-01       Impact factor: 2.816

5.  Clinical and polysomnographic predictors of the natural history of poor sleep in the general population.

Authors:  Julio Fernandez-Mendoza; Alexandros N Vgontzas; Edward O Bixler; Ravi Singareddy; Michele L Shaffer; Susan L Calhoun; Maria Karataraki; Antonio Vela-Bueno; Duanping Liao
Journal:  Sleep       Date:  2012-05-01       Impact factor: 5.849

Review 6.  Cognitive behavioral treatment of insomnia.

Authors:  Jacob Williams; Alicia Roth; Karlyn Vatthauer; Christina S McCrae
Journal:  Chest       Date:  2013-02-01       Impact factor: 9.410

7.  Prevalence and symptoms of occult sleep disordered breathing among older veterans with insomnia.

Authors:  Constance H Fung; Jennifer L Martin; Joseph M Dzierzewski; Stella Jouldjian; Karen Josephson; Michelle Park; Cathy Alessi
Journal:  J Clin Sleep Med       Date:  2013-11-15       Impact factor: 4.062

8.  Sleep-wake misperception in sleep apnea patients undergoing diagnostic versus titration polysomnography.

Authors:  Jelina Castillo; Balaji Goparaju; Matt T Bianchi
Journal:  J Psychosom Res       Date:  2014-03-22       Impact factor: 3.006

9.  Efficacy of eight months of nightly zolpidem: a prospective placebo-controlled study.

Authors:  Surilla Randall; Timothy A Roehrs; Thomas Roth
Journal:  Sleep       Date:  2012-11-01       Impact factor: 5.849

10.  Gender Differences in the Efficacy and Safety of Chronic Nightly Zolpidem.

Authors:  Timothy A Roehrs; Thomas Roth
Journal:  J Clin Sleep Med       Date:  2016-03       Impact factor: 4.062

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