Literature DB >> 20890487

β(1,3) Branched heptadeca- and linear hexadeca-saccharides possessing an aminoalkyl group as a strong ligand to dectin-1.

Hiroshi Tanaka1, Tetsuya Kawai, Yoshiyuki Adachi, Naohito Ohno, Takashi Takahashi.   

Abstract

In this report, we describe the convergent synthesis of β(1,3) oligosaccharides containing an aminoalkyl group. The branched heptadecasaccharide and linear hexadecasaccharide acted as ligands of dectin-1 whose binding affinity was only 10-fold weaker than that of natural SPG and exhibited dectin-1 agonist activity.

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Year:  2010        PMID： 20890487     DOI： 10.1039/c0cc03153d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

1.  Glycal assembly by the in situ generation of glycosyl dithiocarbamates.

Authors:  Panuwat Padungros; Laura Alberch; Alexander Wei
Journal:  Org Lett       Date:  2012-06-11       Impact factor: 6.005

2.  Synthesis and Evaluation of Oligomeric Thioether-Linked Carbacyclic β-(1→3)-Glucan Mimetics.

Authors:  Peng Wen; Václav Větvička; David Crich
Journal:  J Org Chem       Date:  2019-04-15       Impact factor: 4.354

3.  β-(1→3)-Glucan-mannitol conjugates: scope and amazing results.

Authors:  Karine Descroix; Frank Jamois; Jean-Claude Yvin; Vaclav Vetvicka; Vincent Ferrières
Journal:  Ann Transl Med       Date:  2014-02

4.  Synthesis and immunological studies of linear oligosaccharides of β-glucan as antigens for antifungal vaccine development.

Authors:  Guochao Liao; Zhifang Zhou; Srinivas Burgula; Jun Liao; Cheng Yuan; Qiuye Wu; Zhongwu Guo
Journal:  Bioconjug Chem       Date:  2015-02-11       Impact factor: 4.774

5.  Synthesis and Evaluation of 1,5-Dithia-d-laminaribiose, Triose, and Tetraose as Truncated β-(1→3)-Glucan Mimetics.

Authors:  Xiaoxiao Liao; Václav Větvička; David Crich
Journal:  J Org Chem       Date:  2018-12-04       Impact factor: 4.354

6.  NMR study of short β(1-3)-glucans provides insights into the structure and interaction with Dectin-1.

Authors:  Shinya Hanashima; Akemi Ikeda; Hiroshi Tanaka; Yoshiyuki Adachi; Naohito Ohno; Takashi Takahashi; Yoshiki Yamaguchi
Journal:  Glycoconj J       Date:  2013-11-29       Impact factor: 2.916

7.  A Convergent Synthesis of 6-O-Branched β-Glucan Oligosaccharides.

Authors:  Guochao Liao; Srinivas Burgula; Zhifang Zhou; Zhongwu Guo
Journal:  European J Org Chem       Date:  2015-05-01

8.  Influence of side chain conformation and configuration on glycosyl donor reactivity and selectivity as illustrated by sialic acid donors epimeric at the 7-position.

Authors:  Pavan K Kancharla; David Crich
Journal:  J Am Chem Soc       Date:  2013-12-09       Impact factor: 15.419

Review 9.  The Road to Structurally Defined β-Glucans.

Authors:  Patrick Ross; Mark P Farrell
Journal:  Chem Rec       Date:  2021-05-19       Impact factor: 6.935

Review 10.  Recent Advances in the Synthesis of Glycoconjugates for Vaccine Development.

Authors:  Cinzia Colombo; Olimpia Pitirollo; Luigi Lay
Journal:  Molecules       Date:  2018-07-13       Impact factor: 4.411
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