Literature DB >> 20889872

Quantiferon-Leishmania as an epidemiological tool for evaluating the exposure to Leishmania infection.

Nevin Turgay1, I Cuneyt Balcioglu, Seray Ozensoy Toz, Yusuf Ozbel, Stephen L Jones.   

Abstract

The aim of the present preliminary study was to investigate the potential of measurement of IFN-γ secretion by T cells into blood plasma using QuantiFERON assay with leishmanial antigens to determine the presence of Leishmania infection. Blood samples from cured visceral (N = 18), and cutaneous (N = 20) leishmaniasis cases, and 20 healthy controls were tested. The IFN-γ responses to Leishmania major H2B and Leishmania infantum H2B antigens were detected from the majority of treated old visceral leishmaniasis cases, but not from controls. Future studies using larger groups will be required to establish the true potential of the assay for epidemiological screening of leishmaniasis.

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Year:  2010        PMID： 20889872      PMCID： PMC2946749          DOI： 10.4269/ajtmh.2010.09-0605

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  9 in total

1.  QuantiFERON-TB GOLD--An innovation in tuberculosis screening.

Authors:  Christopher J Mol; Susan M Koethe
Journal:  AAOHN J       Date:  2006-06

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Authors:  Kamlesh Gidwani; Madhukar Rai; Jaya Chakravarty; Marleen Boelaert; Shyam Sundar
Journal:  Am J Trop Med Hyg       Date:  2009-04       Impact factor: 2.345

3.  Cell-mediated immune response to tuberculosis antigens: comparison of skin testing and measurement of in vitro gamma interferon production in whole-blood culture.

Authors:  R K Katial; J Hershey; T Purohit-Seth; J T Belisle; P J Brennan; J S Spencer; R J Engler
Journal:  Clin Diagn Lab Immunol       Date:  2001-03

4.  Comparison of a whole-blood interferon gamma assay with tuberculin skin testing for detecting latent Mycobacterium tuberculosis infection.

Authors:  G H Mazurek; P A LoBue; C L Daley; J Bernardo; A A Lardizabal; W R Bishai; M F Iademarco; J S Rothel
Journal:  JAMA       Date:  2001-10-10       Impact factor: 56.272

5.  Loss of leishmanin skin test antigen sensitivity and potency in a longitudinal study of visceral leishmaniasis in Bangladesh.

Authors:  Caryn Bern; Josef Amann; Rashidul Haque; Rajib Chowdhury; Mustakim Ali; Katie M Kurkjian; Louise Vaz; Yukiko Wagatsuma; Robert F Breiman; W Evan Secor; James H Maguire
Journal:  Am J Trop Med Hyg       Date:  2006-10       Impact factor: 2.345

Review 6.  Leishmaniasis.

Authors:  B L Herwaldt
Journal:  Lancet       Date:  1999-10-02       Impact factor: 79.321

7.  Evaluation of leishmanin skin test and its relationship with the clinical form and duration of cutaneous leishmaniasis.

Authors:  Giti Sadeghian; Ali Momeni; Amir Hossein Siadat; Pedram Yousefi
Journal:  Dermatol Online J       Date:  2006-12-10

Review 8.  T-cell interferon-gamma release assays for the rapid immunodiagnosis of tuberculosis: clinical utility in high-burden vs. low-burden settings.

Authors:  Keertan Dheda; Richard van Zyl Smit; Motasim Badri; Madhukar Pai
Journal:  Curr Opin Pulm Med       Date:  2009-05       Impact factor: 3.155

9.  Differentiation of T cell lymphokine gene expression: the in vitro acquisition of T cell memory.

Authors:  S Ehlers; K A Smith
Journal:  J Exp Med       Date:  1991-01-01       Impact factor: 14.307
  9 in total
  13 in total

1.  Th1/Th2 cytokine profile in patients coinfected with HIV and Leishmania in Brazil.

Authors:  Maria Zilma Andrade Rodrigues; Maria Fernanda Rios Grassi; Sanjay Mehta; Xing-Quan Zhang; Luana Leandro Gois; Robert T Schooley; Roberto Badaro
Journal:  Clin Vaccine Immunol       Date:  2011-08-10

2.  Synergistic antigen combinations for the development of interferon gamma release assays for paucibacillary leprosy.

Authors:  R M Oliveira; E M Hungria; A de Araújo Freitas; A L O M de Sousa; M B Costa; S G Reed; M S Duthie; M M A Stefani
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-03-12       Impact factor: 3.267

3.  Assessment of interferon-γ levels and leishmanin skin test results in persons recovered for leishmaniasis.

Authors:  Mohammad H Alimohammadian; Stephen L Jones; Haideh Darabi; Farhad Riazirad; Soheila Ajdary; Aliakbar Shabani; Mohammad A Rezaee; Mehdi Mohebali; Zohreh Hosseini; Farrokh Modabber
Journal:  Am J Trop Med Hyg       Date:  2012-07       Impact factor: 2.345

Review 4.  Whole blood assay and visceral leishmaniasis: Challenges and promises.

Authors:  Om Prakash Singh; Shyam Sundar
Journal:  Immunobiology       Date:  2014-01-31       Impact factor: 3.144

5.  Interferon-gamma release assay (modified QuantiFERON) as a potential marker of infection for Leishmania donovani, a proof of concept study.

Authors:  Kamlesh Gidwani; Stephen Jones; Rajiv Kumar; Marleen Boelaert; Shyam Sundar
Journal:  PLoS Negl Trop Dis       Date:  2011-04-19

6.  Prevalence and determinants of Leishmania major infection in emerging and old foci in Tunisia.

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Review 7.  Visceral leishmaniasis and HIV coinfection in the Mediterranean region.

Authors:  Begoña Monge-Maillo; Francesca F Norman; Israel Cruz; Jorge Alvar; Rogelio López-Vélez
Journal:  PLoS Negl Trop Dis       Date:  2014-08-21

Review 8.  A review of the leishmanin skin test: A neglected test for a neglected disease.

Authors:  Jessica Carstens-Kass; Kayla Paulini; Patrick Lypaczewski; Greg Matlashewski
Journal:  PLoS Negl Trop Dis       Date:  2021-07-22

Review 9.  A screen-and-treat strategy targeting visceral leishmaniasis in HIV-infected individuals in endemic East African countries: the way forward?

Authors:  Johan van Griensven; Ermias Diro; Rogelio Lopez-Velez; Koert Ritmeijer; Marleen Boelaert; Ed E Zijlstra; Asrat Hailu; Lutgarde Lynen
Journal:  PLoS Negl Trop Dis       Date:  2014-08-07

10.  Cytokine Release Assays as Tests for Exposure to Leishmania, and for Confirming Cure from Leishmaniasis, in Solid Organ Transplant Recipients.

Authors:  Eugenia Carrillo; Nerea Carrasco-Antón; Francisco López-Medrano; Efrén Salto; Laura Fernández; Juan Víctor San Martín; Jorge Alvar; Jose María Aguado; Javier Moreno
Journal:  PLoS Negl Trop Dis       Date:  2015-10-23
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