Literature DB >> 20887888

How to survive aneuploidy.

Bulent Cetin1, Don W Cleveland.   

Abstract

Aneuploidy, or an abnormal number of chromosomes, adversely affects cell growth, but it is also linked with cancer and tumorigenesis. Now, Torres et al. (2010) help to resolve this paradox by demonstrating that aneuploid yeast cells can evolve mutations in the proteasome protein degradation pathway that alleviate imbalances in protein production and increase the cell's proliferative capacities.
Copyright © 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID: 20887888      PMCID: PMC2955074          DOI: 10.1016/j.cell.2010.09.030

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  9 in total

1.  Multiple associated proteins regulate proteasome structure and function.

Authors:  David S Leggett; John Hanna; Anna Borodovsky; Bernat Crosas; Marion Schmidt; Rohan T Baker; Thomas Walz; Hidde Ploegh; Daniel Finley
Journal:  Mol Cell       Date:  2002-09       Impact factor: 17.970

2.  Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.

Authors:  John Hanna; Nathaniel A Hathaway; Yoshiko Tone; Bernat Crosas; Suzanne Elsasser; Donald S Kirkpatrick; David S Leggett; Steven P Gygi; Randall W King; Daniel Finley
Journal:  Cell       Date:  2006-10-06       Impact factor: 41.582

3.  G-418, an elongation inhibitor of 80 S ribosomes.

Authors:  S Bar-Nun; Y Shneyour; J S Beckmann
Journal:  Biochim Biophys Acta       Date:  1983-10-13

Review 4.  Mitotic chromosomal instability and cancer: mouse modelling of the human disease.

Authors:  Juan-Manuel Schvartzman; Rocio Sotillo; Robert Benezra
Journal:  Nat Rev Cancer       Date:  2010-02       Impact factor: 60.716

5.  Effects of aneuploidy on cellular physiology and cell division in haploid yeast.

Authors:  Eduardo M Torres; Tanya Sokolsky; Cheryl M Tucker; Leon Y Chan; Monica Boselli; Maitreya J Dunham; Angelika Amon
Journal:  Science       Date:  2007-08-17       Impact factor: 47.728

Review 6.  Chromosome aberrations in solid tumors.

Authors:  Donna G Albertson; Colin Collins; Frank McCormick; Joe W Gray
Journal:  Nat Genet       Date:  2003-08       Impact factor: 38.330

7.  A versatile method for efficient YAC transfer between any two strains.

Authors:  Y Hugerat; F Spencer; D Zenvirth; G Simchen
Journal:  Genomics       Date:  1994-07-01       Impact factor: 5.736

Review 8.  Boveri revisited: chromosomal instability, aneuploidy and tumorigenesis.

Authors:  Andrew J Holland; Don W Cleveland
Journal:  Nat Rev Mol Cell Biol       Date:  2009-07       Impact factor: 94.444

9.  Identification of aneuploidy-tolerating mutations.

Authors:  Eduardo M Torres; Noah Dephoure; Amudha Panneerselvam; Cheryl M Tucker; Charles A Whittaker; Steven P Gygi; Maitreya J Dunham; Angelika Amon
Journal:  Cell       Date:  2010-09-16       Impact factor: 41.582

  9 in total
  4 in total

1.  Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans.

Authors:  Min Ni; Marianna Feretzaki; Wenjun Li; Anna Floyd-Averette; Piotr Mieczkowski; Fred S Dietrich; Joseph Heitman
Journal:  PLoS Biol       Date:  2013-09-10       Impact factor: 8.029

2.  Leaf rolling and stem fasciation in grass pea (Lathyrus sativus L.) mutant are mediated through glutathione-dependent cellular and metabolic changes and associated with a metabolic diversion through cysteine during phenotypic reversal.

Authors:  Dibyendu Talukdar; Tulika Talukdar
Journal:  Biomed Res Int       Date:  2014-05-28       Impact factor: 3.411

3.  Molecular characterization of Chlamydomonas reinhardtii telomeres and telomerase mutants.

Authors:  Stephan Eberhard; Sona Valuchova; Julie Ravat; Jaroslav Fulneček; Pascale Jolivet; Sandrine Bujaldon; Stéphane D Lemaire; Francis-André Wollman; Maria Teresa Teixeira; Karel Riha; Zhou Xu
Journal:  Life Sci Alliance       Date:  2019-06-03

4.  A conserved expression signature predicts growth rate and reveals cell & lineage-specific differences.

Authors:  Zhisheng Jiang; Serena F Generoso; Marta Badia; Bernhard Payer; Lucas B Carey
Journal:  PLoS Comput Biol       Date:  2021-11-11       Impact factor: 4.475

  4 in total

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