Literature DB >> 20885312

Deep intrastromal bevacizumab injection for management of corneal stromal vascularization after deep anterior lamellar keratoplasty, a novel technique.

Mohammad Naser Hashemian1, Mohammad Ali Zare, Firoozeh Rahimi, Mehrdad Mohammadpour.   

Abstract

PURPOSE: To report the effect of intrastromal injection of bevacizumab in an eye with extensive corneal stromal vascularization after deep anterior lamellar keratoplasty.
METHODS: Bevacizumab (2.5 mg/1 mL) was injected into the deep corneal stroma of an eye with severe and extensive stromal vascularization.
RESULTS: Corneal vascularization regressed dramatically after deep stromal injection of bevacizumab with no recurrence after 6 months. Visual acuity was improved, and the patient's complaints subsided.
CONCLUSIONS: Corneal intrastromal injection of bevacizumab can be considered for management of intrastromal vascularization after deep anterior lamellar keratoplasty.

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Year:  2011        PMID: 20885312     DOI: 10.1097/ICO.0b013e3181e291a6

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  15 in total

1.  Update on the Management of High-Risk Penetrating Keratoplasty.

Authors:  Sayena Jabbehdari; Alireza Baradaran Rafii; Ghasem Yazdanpanah; Pedram Hamrah; Edward J Holland; Ali R Djalilian
Journal:  Curr Ophthalmol Rep       Date:  2017-02-02

2.  The effect of different doses of subconjunctival bevacizumab injection on corneal neovascularization.

Authors:  Banu Torun Acar; Elvin Halili; Suphi Acar
Journal:  Int Ophthalmol       Date:  2013-02-13       Impact factor: 2.031

3.  Intrastromal delivery of bevacizumab using microneedles to treat corneal neovascularization.

Authors:  Yoo C Kim; Hans E Grossniklaus; Henry F Edelhauser; Mark R Prausnitz
Journal:  Invest Ophthalmol Vis Sci       Date:  2014-09-11       Impact factor: 4.799

Review 4.  Ocular delivery of proteins and peptides: Challenges and novel formulation approaches.

Authors:  Abhirup Mandal; Dhananjay Pal; Vibhuti Agrahari; Hoang My Trinh; Mary Joseph; Ashim K Mitra
Journal:  Adv Drug Deliv Rev       Date:  2018-01-13       Impact factor: 15.470

Review 5.  Corneal neovascularization: an anti-VEGF therapy review.

Authors:  Jin-Hong Chang; Nitin K Garg; Elisa Lunde; Kyu-Yeon Han; Sandeep Jain; Dimitri T Azar
Journal:  Surv Ophthalmol       Date:  2012-09       Impact factor: 6.048

6.  Corneal thinning following bevacizumab intrastromal injection for the treatment of idiopathic lipid keratopathy.

Authors:  Kristie J Sun; Albert S Jun; Kelley Bohm; Daniel Daroszewski; Samir Jabbour
Journal:  Am J Ophthalmol Case Rep       Date:  2022-06-24

Review 7.  Ocular delivery of macromolecules.

Authors:  Yoo Chun Kim; Bryce Chiang; Xianggen Wu; Mark R Prausnitz
Journal:  J Control Release       Date:  2014-07-03       Impact factor: 9.776

8.  Intrastromal bevacizumab in the management of corneal neovascularization: a retrospective review.

Authors:  Archana A Gupta; Danny A Mammo; Michael A Page
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2019-11-12       Impact factor: 3.117

9.  Prophylactic effect of topical silica nanoparticles as a novel antineovascularization agent for inhibiting corneal neovascularization following chemical burn.

Authors:  Mehrdad Mohammadpour; Mahmoud Jabbarvand; Hassan Hashemi; Elham Delrish
Journal:  Adv Biomed Res       Date:  2015-06-04

10.  Long-term Outcomes of Amniotic Membrane Transplantation in Contact Lens-Induced Pseudomonas Keratitis with Impending Corneal Perforation.

Authors:  Mehrdad Mohammadpour; Fatemeh Alsadat Sabet
Journal:  J Ophthalmic Vis Res       Date:  2016 Jan-Mar
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