Literature DB >> 20881598

The association of serum ionized calcium and vitamin D with adult cognitive performance.

Anna-Maija Tolppanen1, Dylan M Williams, Debbie A Lawlor.   

Abstract

BACKGROUND: High serum calcium levels have been associated with cognitive decline in older adults. These associations have not been studied in younger adults. The possible association of vitamin D with cognitive function, independent of calcium, is unknown.
METHODS: A cross-sectional study of associations of serum ionized calcium and 25-hydroxyvitamin D levels with cognitive function in younger adults (20-59 years) and older adults (60-90 years) was conducted using data from the US third National Health and Nutrition Examination Survey (NHANES III).
RESULTS: Neither serum ionized calcium nor 25-hydroxyvitamin D was associated with cognitive function in either age group. For example, the confounder-adjusted mean difference in reaction time in young adults was 0.00 (95% confidence interval = -0.07 to 0.06) per 1 SD calcium.
CONCLUSION: Our results do not support an important role for calcium or vitamin D in cognitive performance in adults.

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Year:  2011        PMID： 20881598      PMCID： PMC3957006          DOI： 10.1097/EDE.0b013e3181f74683

Source DB:  PubMed          Journal:  Epidemiology        ISSN： 1044-3983            Impact factor:   4.822


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