Literature DB >> 20881514

Continuous infusion of bupivacaine reduces postoperative morphine use in adolescent idiopathic scoliosis after posterior spine fusion.

Patrick A Ross1, Brendan M Smith, Vernon T Tolo, Robinder G Khemani.   

Abstract

STUDY
DESIGN: Retrospective analysis.
OBJECTIVE: To determine if an infusion of bupivacaine will reduce the need for intravenous opioids following posterior spine fusion. SUMMARY OF BACKGROUND DATA: Adolescent idiopathic scoliosis is estimated to occur with a frequency of 1% to 3% among the at-risk age group of 10 to 18 years. A small percentage of these patients will require surgical intervention. Data are limited regarding continuous infusion of local anesthetic after posterior spine fusion for pain control. METHODS.: Retrospective review of children 10 to 18 years with idiopathic scoliosis admitted to a tertiary care, 20-bed pediatric intensive care unit (P pediatric intensive care unit), following posterior spine fusion. The primary outcome was postoperative opioid use stratified by the presence of a catheter for continuous bupivacaine. Secondary outcomes included pain scores, side effect management, depth of catheter placement, and fluid resuscitation.
RESULTS: Two hundred and forty-four children were eligible, 129 received a catheter for continuous bupivacaine, 115 did not. There were no differences in demographics. Significantly fewer patients receiving bupivacaine required a continuous basal infusion of morphine (32.6% vs. 85.2%, P < 0.001) resulting in an overall reduction opioid use on postoperative day 1 (18.9 vs. 26.4 mg, P < 0.001). Overall, pain scores were low in both groups. Limiting the analysis to only those with a bupivacaine catheter, the depth of catheter placement did not impact postoperative opioid use (P > 0.15).
CONCLUSION: The use of a continuous infusion of bupivacaine provided good analgesia with low pain scores. The significant reduction in basal morphine use may reflect a replacement by bupivacaine, although this is limited by potential treatment bias. Multivariate analysis was required to control for ongoing changes in anesthesia practice over the many years of the study. The optimal depth of catheter placement is unclear from this analysis and should be studied prospectively.

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Year:  2011        PMID: 20881514     DOI: 10.1097/BRS.0b013e3181f352d1

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  8 in total

1.  Regional anaesthesia and postoperative analgesia techniques for spine surgery - a review.

Authors:  Najoua Mokraï Benyahia; Ann Verster; Vera Saldien; Margaretha Breebaart; Luc Sermeus; Marcel Vercauteren
Journal:  Rom J Anaesth Intensive Care       Date:  2015-04

2.  High-volume, multilevel local anesthetics-Epinephrine infiltration in kyphoscoliosis surgery: Intra and postoperative analgesia.

Authors:  Alaa Mazy; Mohamed Serry; Mohamed Kassem
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2021-04-10

Review 3.  Postoperative pain management in patients undergoing posterior spinal fusion for adolescent idiopathic scoliosis: a narrative review.

Authors:  Hiroyuki Seki; Satoshi Ideno; Taiga Ishihara; Kota Watanabe; Morio Matsumoto; Hiroshi Morisaki
Journal:  Scoliosis Spinal Disord       Date:  2018-09-12

4.  Current Trends in Pediatric Spine Deformity Surgery: Multimodal Pain Management and Rapid Recovery.

Authors:  Sagar A Shah; Richard Guidry; Abhishek Kumar; Tyler White; Andrew King; Michael J Heffernan
Journal:  Global Spine J       Date:  2019-09-22

5.  Efficacy of surgeon-directed postoperative local injection with an analgesic mixture in posterior fusion surgery for adolescent idiopathic scoliosis.

Authors:  Hiroto Makino; Shoji Seki; Katsuhiko Kamei; Yasuhito Yahara; Yoshiharu Kawaguchi
Journal:  BMC Musculoskelet Disord       Date:  2022-03-04       Impact factor: 2.362

6.  Postoperative pain relief using intermittent intrapleural analgesia following thoracoscopic anterior correction for progressive adolescent idiopathic scoliosis.

Authors:  Stephen Ac Morris; Maree T Izatt; Clayton J Adam; Robert D Labrom; Geoffrey N Askin
Journal:  Scoliosis       Date:  2013-11-16

7.  Postoperative pain management after spinal fusion surgery: an analysis of the efficacy of continuous infusion of local anesthetics.

Authors:  Richard A K Reynolds; Julie E Legakis; Jillian Tweedie; Youngkey Chung; Emily J Ren; Patricia A Bevier; Ronald L Thomas; Suresh T Thomas
Journal:  Global Spine J       Date:  2013-03-02

Review 8.  Guidelines for Opioid Prescribing in Children and Adolescents After Surgery: An Expert Panel Opinion.

Authors:  Lorraine I Kelley-Quon; Matthew G Kirkpatrick; Robert L Ricca; Robert Baird; Calista M Harbaugh; Ashley Brady; Paula Garrett; Hale Wills; Jonathan Argo; Karen A Diefenbach; Marion C W Henry; Juan E Sola; Elaa M Mahdi; Adam B Goldin; Shawn D St Peter; Cynthia D Downard; Kenneth S Azarow; Tracy Shields; Eugene Kim
Journal:  JAMA Surg       Date:  2021-01-01       Impact factor: 14.766

  8 in total

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