BACKGROUND AND AIM OF THE STUDY: The aim of this study is to report the prevalence of menopausal symptoms by severity among the Finnish female population and the association of their symptoms with lifestyle (smoking, use of alcohol, physical activity) and body mass index (BMI). MATERIAL AND METHODS: Health 2000 is a nationally representative population-based study of Finnish adults. Data were collected by home interview, three self-administered questionnaires and a clinical examination by a physician. This study included women aged 45-64 years (n=1427). All symptoms included menopause-specific symptoms. Both univariate analysis and a factor analysis based on symptom factors were performed by menopausal group. Multiple regression analysis included each symptom factor as a dependent variable and confounding and lifestyle factors (age, education, smoking, alcohol use, physical activity, BMI, use of hormonal replacement therapy (HRT) and chronic disease status). RESULTS: Over one-third (38%) of the premenopausal, half of the perimenopausal, and 54% of both postmenopausal and hysterectomized women reported bothersome symptoms. The difference between pre- and perimenopausal women was largest and statistically most significant in the case of back pain and hot flushes. Physically active women reported fewer somatic symptoms than did women with a sedentary lifestyle. Smoking was not related to vasomotor symptoms. CONCLUSION: Bothersome symptoms are common in midlife, regardless of menopausal status. Inverse association between physical activity and menopausal symptoms needs to be confirmed in randomized trials.
BACKGROUND AND AIM OF THE STUDY: The aim of this study is to report the prevalence of menopausal symptoms by severity among the Finnish female population and the association of their symptoms with lifestyle (smoking, use of alcohol, physical activity) and body mass index (BMI). MATERIAL AND METHODS: Health 2000 is a nationally representative population-based study of Finnish adults. Data were collected by home interview, three self-administered questionnaires and a clinical examination by a physician. This study included women aged 45-64 years (n=1427). All symptoms included menopause-specific symptoms. Both univariate analysis and a factor analysis based on symptom factors were performed by menopausal group. Multiple regression analysis included each symptom factor as a dependent variable and confounding and lifestyle factors (age, education, smoking, alcohol use, physical activity, BMI, use of hormonal replacement therapy (HRT) and chronic disease status). RESULTS: Over one-third (38%) of the premenopausal, half of the perimenopausal, and 54% of both postmenopausal and hysterectomized women reported bothersome symptoms. The difference between pre- and perimenopausal women was largest and statistically most significant in the case of back pain and hot flushes. Physically active women reported fewer somatic symptoms than did women with a sedentary lifestyle. Smoking was not related to vasomotor symptoms. CONCLUSION: Bothersome symptoms are common in midlife, regardless of menopausal status. Inverse association between physical activity and menopausal symptoms needs to be confirmed in randomized trials.
Authors: Lisa Gallicchio; Susan R Miller; Judith Kiefer; Teresa Greene; Howard A Zacur; Jodi A Flaws Journal: Menopause Date: 2015-10 Impact factor: 2.953
Authors: Yvonne C Lee; Arun S Karlamangla; Zhi Yu; Chih-Chin Liu; Joel S Finkelstein; Gail A Greendale; Siobán D Harlow; Daniel H Solomon Journal: J Pain Date: 2016-11-09 Impact factor: 5.820
Authors: Rebecca B Lawn; Kristen M Nishimi; Yongjoo Kim; Sun Jae Jung; Andrea L Roberts; Jennifer A Sumner; Rebecca C Thurston; Lori B Chibnik; Eric B Rimm; Andrew D Ratanatharathorn; Shaili C Jha; Karestan C Koenen; Shelley S Tworoger; Laura D Kubzansky Journal: Cancer Epidemiol Biomarkers Prev Date: 2020-12-21 Impact factor: 4.254
Authors: Laura López-Ríos; Miguel A Barber; Julia Wiebe; Rubén P Machín; Tanausú Vega-Morales; Ricardo Chirino Journal: PLoS One Date: 2021-07-21 Impact factor: 3.240