| Literature DB >> 20868526 |
Gail Gilchrist1, Kelsey Hegarty, Patty Chondros, Helen Herrman, Jane Gunn.
Abstract
BACKGROUND: Depressive symptoms, intimate partner violence and hazardous drinking are common among patients attending general practice. Despite the high prevalence of these three problems; the relationship between them remains relatively unexplored.Entities:
Mesh:
Year: 2010 PMID: 20868526 PMCID: PMC2954955 DOI: 10.1186/1471-2296-11-72
Source DB: PubMed Journal: BMC Fam Pract ISSN: 1471-2296 Impact factor: 2.497
Depressive symptoms by patient characteristics and test for interaction for patient characteristics and sex
| N | Mean | (SD) | Diff | (95% CI) | P-value | Interaction term | P-value | |
|---|---|---|---|---|---|---|---|---|
| Male | 2491 | 9.76 | (10.08) | Ref | ||||
| Female | 4991 | 10.9 | (10.53) | 1.03 | (0.51, 1.54) | < 0.001 | ||
| 18-24 | 323 | 14.4 | (11.44) | Ref | 0.18 | |||
| 25-34 | 842 | 12.54 | (10.82) | -1.84 | (-3.15, -0.52) | < 0.001 | -3.39 | |
| 35-44 | 1443 | 11.15 | (10.88) | -3.10 | (-4.34, -1.86) | -2.88 | ||
| 45-54 | 1763 | 10.83 | (10.90) | -3.47 | (-4.69, -2.25) | -2.50 | ||
| 55-64 | 1694 | 9.67 | (9.95) | -4.59 | (-5.81, -3.36) | -3.02 | ||
| 65-75 | 1361 | 8.37 | (8.48) | -5.87 | (-7.12, -4.61) | -1.68 | ||
| Not ever afraid | 6042 | 9.23 | (9.36) | Ref | ||||
| Ever afraid of partner | 1202 | 16.49 | (12.55) | 7.14 | (6.52, 7.76) | < 0.001 | -2.5 | 0.003 |
| No | 6218 | 10.01 | (10.09) | Ref | ||||
| Yes | 1228 | 12.93 | (11.42) | 2.97 | (2.34, 3.60) | < 0.001 | 1.41 | 0.03 |
| No | 6107 | 9.55 | (9.56) | Ref | ||||
| Yes | 1357 | 14.76 | (12.58) | 5.12 | (4.52, 5.72) | < 0.001 | -1.1 | 0.09 |
| Never married/single | 1334 | 13.46 | (11.63) | Ref | < 0.001 | 0.01 | ||
| Widowed/divorced/aaseparated | 1312 | 13.38 | (12.28) | -0.11 | (-0.88, 0.66) | -1.37 | ||
| Married | 4770 | 8.9 | (9.04) | -4.51 | (-5.14, -3.89) | 0.82 | ||
| Exclusively heterosexual | 6803 | 10.16 | (10.21) | Ref | ||||
| Not exclusively heterosexual | 354 | 14.65 | (11.76) | 4.44 | (3.31, 5.57) | < 0.001 | 2.35 | 0.05 |
| No | 6476 | 10.11 | (10.05) | Ref | ||||
| Yes | 996 | 13.17 | (12.05) | 3.09 | (2.40, 3.78) | < 0.001 | -3.82 | < 0.001 |
| Employed/Student | 4802 | 9.93 | (9.87) | Ref | < 0.001 | 0.75 | ||
| Not employed/not in paid employment | 2274 | 9.89 | (9.72) | 0.07 | (-0.44, 0.57) | -0.06 | ||
| Unable to work | 401 | 20.85 | (13.85) | 11.01 | (9.98, 12.04) | 0.77 | ||
| Completed year 12 or less | 4182 | 11.07 | (10.57) | Ref | < 0.001 | 0.57 | ||
| Certificate or diploma | 1566 | 10.53 | (10.64) | -0.71 | (-1.31, -0.11) | 0.65 | ||
| Bachelor degree or higher | 1718 | 9.1 | (9.52) | -2.18 | (-2.79, -1.57) | 0.41 | ||
| No | 5518 | 9.6 | (9.60) | Ref | ||||
| Yes | 1890 | 13.11 | (12.06) | 3.62 | (3.08, 4.16) | < 0.001 | -0.28 | 0.62 |
| Urban (RRMA 1 & 2) | 5063 | 10.56 | (10.46) | Ref | ||||
| Rural (RRMA 3-5) | 2433 | 10.42 | (10.22) | -0.14 | (-1.22, 0.95) | 0.81 | -0.55 | 0.32 |
| Other | 1384 | 10.51 | (10.20) | Ref | -0.11 | 0.86 | ||
| Australia | 6093 | 10.53 | (10.43) | 0.11 | (-0.50, 0.72) | 0.72 | ||
| No | 4964 | 8.81 | (9.06) | Ref | ||||
| Yes | 2363 | 14.06 | (12.00) | 5.33 | (4.83, 5.82) | < 0.001 | -1.64 | 0.002 |
| Excellent | 763 | 5.4 | (6.79) | Ref | < 0.001 | 0.05 | ||
| Very good | 2782 | 7.37 | (7.69) | 2.04 | (1.28, 2.78) | 1.53 | ||
| Good | 2644 | 11.54 | (10.00) | 6.18 | (5.42, 6.94) | 2.07 | ||
| Fair | 1012 | 17.19 | (12.28) | 11.9 | (11.02, 12.79) | 0.37 | ||
| Poor | 206 | 25 | (14.18) | 19.6 | (18.19, 21.08) | 1.83 |
Ref = reference category for patient characteristics
SD = Standard deviation
Difference in mean depressive symptoms (Diff), respective 95% confidence intervals (CI) and p-values calculated using mixed effects linear regression using restricted maximum likelihood estimation (REML), treating GP practice as a random effect
Interaction term for each patient characteristic and sex and related p-value
Depressive symptoms by patient characteristics separately for males and females
| Males (N = 2491) | ||||||
|---|---|---|---|---|---|---|
| Not ever afraid | 2185 | 8.88 | (9.28) | Ref | ||
| Ever afraid of partner | 179 | 18.23 | (12.61) | 9.17 | (7.66, 10.69) | < 0.001 |
| No | 1841 | 9.09 | (9.62) | Ref | ||
| Yes | 620 | 11.52 | (11.02) | 2.51 | (1.58, 3.45) | < 0.001 |
| No | 2051 | 8.73 | (8.98) | Ref | ||
| Yes | 430 | 14.73 | (13.14) | 5.84 | (4.78, 6.89) | < 0.001 |
| Never married/single | 423 | 13.16 | (11.92) | < 0.001 | ||
| Widowed/divorced/separated | 321 | 14.09 | (12.42) | 0.89 | (-0.59, 2.37) | |
| Married | 1729 | 8.1 | (8.55) | -5.03 | (-6.13, -3.94) | |
| Exclusively heterosexual | 2240 | 9.4 | (9.90) | Ref | ||
| Not exclusively heterosexual | 147 | 12.76 | (11.12) | 3.07 | (1.26, 4.88) | 0.001 |
| No | 2171 | 9.03 | (9.41) | Ref | ||
| Yes | 314 | 14.74 | (12.76) | 5.67 | (4.45, 6.89) | < 0.001 |
| No | 1405 | 7.08 | (7.52) | Ref | ||
| Yes | 1021 | 13.62 | (11.90) | 6.57 | (5.76, 7.38) | < 0.001 |
| Excellent | 205 | 4.9 | (6.05) | Ref | < 0.001 | |
| Very good | 808 | 5.84 | (6.32) | 0.94 | (-0.49, 2.37) | |
| Good | 962 | 9.86 | (9.17) | 4.89 | (3.48, 6.30) | |
| Fair | 397 | 16.58 | (12.18) | 11.71 | (10.13, 13.28) | |
| Poor | 92 | 23.64 | (13.46) | 18.66 | (16.35, 20.96) | |
| Not ever afraid | 3845 | 9.44 | (9.40) | Ref | ||
| Ever afraid of partner | 1022 | 16.19 | (12.52) | 6.67 | (5.99, 7.36) | < 0.001 |
| No | 4364 | 10.41 | (10.27) | Ref | ||
| Yes | 608 | 14.38 | (11.65) | 3.93 | (3.05, 4.80) | < 0.001 |
| No | 4043 | 9.98 | (9.82) | Ref | ||
| Yes | 926 | 14.78 | (12.33) | 4.74 | (4.01, 5.47) | < 0.001 |
| Never married/single | 911 | 13.61 | (11.50) | < 0.001 | ||
| Widowed/divorced/separated | 991 | 13.15 | (12.23) | -0.48 | (-1.40, 0.43) | |
| Married | 3040 | 9.36 | (9.27) | -4.22 | (-4.97, -3.46) | |
| Exclusively heterosexual | 4563 | 10.53 | (10.33) | Ref | ||
| Not exclusively heterosexual | 207 | 15.99 | (12.03) | 5.41 | (3.98, 6.84) | < 0.001 |
| No | 4304 | 10.66 | (10.32) | Ref | ||
| Yes | 682 | 12.44 | (11.65) | 1.85 | (1.02, 2.68) | < 0.001 |
| No | 3552 | 9.5 | (9.53) | Ref | ||
| Yes | 1336 | 14.42 | (12.08) | 4.93 | (4.30, 5.57) | < 0.001 |
| Excellent | 557 | 5.58 | (7.05) | Ref | < 0.001 | |
| Very good | 1969 | 7.99 | (8.11) | 2.47 | (1.59, 3.35) | |
| Good | 1677 | 12.51 | (10.33) | 6.96 | (6.06, 7.86) | |
| Fair | 612 | 17.61 | (12.36) | 12.08 | (11.01, 13.15) | |
| Poor | 114 | 26.1 | (14.71) | 20.48 | (18.60, 22.37) | |
Ref = reference category for patient characteristics
SD = Standard deviation
Difference in mean depressive symptoms (Diff), respective 95% confidence intervals (CI) and p-values calculated using mixed effects linear regression using restricted maximum likelihood estimation (REML), treating GP practice as a random effect
Analysis reported separately for males and females when p-value for interaction was 10% or greater in Table 1
Multivariable analysis for Hazardous drinking in last year and ever-afraid of partner
| Males | ||||||
|---|---|---|---|---|---|---|
| (N = 2336) | (N = 2261) | |||||
| 8.93 | (7.47, 10.40) | < 0.001 | 6.87 | (5.42, 8.33) | < 0.001 | |
| 1.99 | (1.09, 2.88) | < 0.001 | 1.07 | (0.21, 1.94) | 0.015 | |
| 6.45 | (5.75, 7.15) | < 0.001 | 5.26 | (4.55, 5.97) | < 0.001 | |
| 3.20 | (2.33, 4.08) | < 0.001 | 2.23 | (1.35, 3.11) | < 0.001 | |
Model 1 - Adjusted model - Ever afraid of partner and hazardous drinking fitted in the same model, but not adjusted for any other
Model 2 - Adjusted for all factors, except sexuality - Ever afraid of partner and hazardous drinking fitted in the same model adjusted for all factors: Age group, education level, employment status, pension or benefit as main source of income, marital status, live alone, but not sexuality due to large proportion of missing data
Difference in mean depressive symptoms (Diff), respective 95% confidence intervals (CI) and p-values calculated using mixed effects linear regression using restricted maximum likelihood estimation (REML), treating GP practice as a random effect