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Literature DB >> 20860360

Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms.

Abstract

A xanthene-forming condensation reaction yields rhodol and rhodamine dyes carrying a zinc-binding ligand that includes the aniline-type nitrogen donor of the fluorophores. Upon zinc coordination in neutral aqueous solution, rhodol RF3 behaves as a ratiometric sensor, and rhodamine RA1 acts as a turn-off intensity-based indicator. Both fluorescent compounds bind the divalent zinc cation with micromolar affinity.

Entities: Chemical Disease Gene Species

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Year: 2010 PMID： 20860360 PMCID： PMC2956166 DOI： 10.1021/ic101513a

Source DB: PubMed Journal: Inorg Chem ISSN： 0020-1669 Impact factor: 5.165

20 in total

1. Measuring zinc in living cells. A new generation of sensitive and selective fluorescent probes.

Authors: K R Gee; Z-L Zhou; D Ton-That; S L Sensi; J H Weiss
Journal: Cell Calcium Date: 2002-05 Impact factor: 6.817

Review 2. Metals and Alzheimer's disease.

Authors: Paul A Adlard; Ashley I Bush
Journal: J Alzheimers Dis Date: 2006-11 Impact factor: 4.472

Review 3. Ratiometric and near-infrared molecular probes for the detection and imaging of zinc ions.

Authors: Priya Carol; Sivaramapanicker Sreejith; Ayyappanpillai Ajayaghosh
Journal: Chem Asian J Date: 2007-03-05

Review 4. A new trend in rhodamine-based chemosensors: application of spirolactam ring-opening to sensing ions.

Authors: Ha Na Kim; Min Hee Lee; Hyun Jung Kim; Jong Seung Kim; Juyoung Yoon
Journal: Chem Soc Rev Date: 2008-06-23 Impact factor: 54.564

5. Design and synthesis of regioisomerically pure unsymmetrical xanthene derivatives for staining live cells and their photochemical properties.

Authors: Shinichiro Kamino; Hayato Ichikawa; Shun-ichi Wada; Yuka Horio; Yoshihide Usami; Takako Yamaguchi; Toshiki Koda; Aki Harada; Kazusa Shimanuki; Masao Arimoto; Mitsunobu Doi; Yoshikazu Fujita
Journal: Bioorg Med Chem Lett Date: 2008-06-21 Impact factor: 2.823

Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms.

1. Measuring zinc in living cells. A new generation of sensitive and selective fluorescent probes.

Review 2. Metals and Alzheimer's disease.

Review 3. Ratiometric and near-infrared molecular probes for the detection and imaging of zinc ions.

Review 4. A new trend in rhodamine-based chemosensors: application of spirolactam ring-opening to sensing ions.

5. Design and synthesis of regioisomerically pure unsymmetrical xanthene derivatives for staining live cells and their photochemical properties.

6. Small-molecule fluorescent sensors for investigating zinc metalloneurochemistry.

Review 7. Metals in neurobiology: probing their chemistry and biology with molecular imaging.

8. The rhodafluor family. An initial study of potential ratiometric fluorescent sensors for Zn2+.

Review 9. The biochemical basis of zinc physiology.

10. Fluorescent rhodol derivatives: versatile, photostable labels and tracers.

1. Understanding zinc quantification with existing and advanced ditopic fluorescent Zinpyr sensors.

Review 2. Fluorescent sensors for measuring metal ions in living systems.

3. Near-Infrared Fluorescent Probes with Large Stokes Shifts for Sensing Zn(II) Ions in Living Cells.

Review 4. Visualizing metal ions in cells: an overview of analytical techniques, approaches, and probes.

Review 5. Tools and techniques for illuminating the cell biology of zinc.

6. Convergent Ca2+ and Zn2+ signaling regulates apoptotic Kv2.1 K+ currents.

7. Rhodamine-Appended Benzophenone Probe for Trace Quantity Detection of Pd²⁺ in Living Cells.

8. Solid-State Emissive Metallo-Supramolecular Assemblies of Quinoline-Based Acyl Hydrazone.