Literature DB >> 20856765

Barriers to enrollment of elderly adults in early-phase cancer clinical trials.

Michele Basche1, Anna E Barón, S Gail Eckhardt, Lodovico Balducci, Martha Persky, Adrah Levin, Nathaniel Jackson, Chan Zeng, Pamela Vranas, John F Steiner.   

Abstract

Potential strategies to overcome barriers to enrollment of seniors into early-phase trials.

Entities:  

Year:  2008        PMID： 20856765      PMCID： PMC2793956          DOI： 10.1200/JOP.0842001

Source DB:  PubMed          Journal:  J Oncol Pract        ISSN： 1554-7477            Impact factor:   3.840


  14 in total

Review 1.  Aging and cancer in America. Demographic and epidemiologic perspectives.

Authors:  R Yancik; L A Ries
Journal:  Hematol Oncol Clin North Am       Date:  2000-02       Impact factor: 3.722

2.  Underrepresentation of patients 65 years of age or older in cancer-treatment trials.

Authors:  L F Hutchins; J M Unger; J J Crowley; C A Coltman; K S Albain
Journal:  N Engl J Med       Date:  1999-12-30       Impact factor: 91.245

Review 3.  Systematic review of barriers to the recruitment of older patients with cancer onto clinical trials.

Authors:  Carol A Townsley; Rita Selby; Lillian L Siu
Journal:  J Clin Oncol       Date:  2005-05-01       Impact factor: 44.544

Review 4.  Cancer statistics, 2004.

Authors:  Ahmedin Jemal; Ram C Tiwari; Taylor Murray; Asma Ghafoor; Alicia Samuels; Elizabeth Ward; Eric J Feuer; Michael J Thun
Journal:  CA Cancer J Clin       Date:  2004 Jan-Feb       Impact factor: 508.702

5.  Representation of older patients in cancer treatment trials.

Authors:  E L Trimble; C L Carter; D Cain; B Freidlin; R S Ungerleider; M A Friedman
Journal:  Cancer       Date:  1994-10-01       Impact factor: 6.860

6.  Obstacles to the accrual of patients to clinical trials in the community setting.

Authors:  R J Winn
Journal:  Semin Oncol       Date:  1994-08       Impact factor: 4.929

7.  Oncologists' reluctance to accrue patients onto clinical trials: an Illinois Cancer Center study.

Authors:  A B Benson; J P Pregler; J A Bean; A W Rademaker; B Eshler; K Anderson
Journal:  J Clin Oncol       Date:  1991-11       Impact factor: 44.544

8.  Barriers to clinical trial participation by older women with breast cancer.

Authors:  M Margaret Kemeny; Bercedis L Peterson; Alice B Kornblith; Hyman B Muss; Judith Wheeler; Ellis Levine; Nancy Bartlett; Gini Fleming; Harvey J Cohen
Journal:  J Clin Oncol       Date:  2003-06-15       Impact factor: 44.544

9.  Enrollment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration.

Authors:  Lilia Talarico; Gang Chen; Richard Pazdur
Journal:  J Clin Oncol       Date:  2004-11-15       Impact factor: 44.544

10.  Understanding the attitudes of the elderly towards enrolment into cancer clinical trials.

Authors:  Carol A Townsley; Kelvin K Chan; Gregory R Pond; Christine Marquez; Lillian L Siu; Sharon E Straus
Journal:  BMC Cancer       Date:  2006-02-08       Impact factor: 4.430
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  22 in total

1.  Caring for the elderly cancer patient: training the next generation of oncologists.

Authors:  Gary H Lyman
Journal:  J Oncol Pract       Date:  2008-07       Impact factor: 3.840

2.  Overturning barriers will take heavy lifting.

Authors:  Harvey Jay Cohen
Journal:  J Oncol Pract       Date:  2008-07       Impact factor: 3.840

3.  The role of age on dose-limiting toxicities in phase I dose-escalation trials.

Authors:  A Schwandt; P J Harris; S Hunsberger; A Deleporte; G L Smith; D Vulih; B D Anderson; S P Ivy
Journal:  Clin Cancer Res       Date:  2014-07-15       Impact factor: 12.531

4.  Do we protect or discriminate? Representation of senior adults in clinical trials.

Authors:  Joanna Kaźmierska
Journal:  Rep Pract Oncol Radiother       Date:  2012-09-26

Review 5.  Health-Related Quality of Life in Older Adults with Colorectal Cancer.

Authors:  Evan Lapinsky; Lillian C Man; Amy R MacKenzie
Journal:  Curr Oncol Rep       Date:  2019-07-29       Impact factor: 5.075

6.  Biological, clinical, and psychosocial correlates at the interface of cancer and aging research.

Authors:  William Dale; Supriya G Mohile; Basil A Eldadah; Edward L Trimble; Richard L Schilsky; Harvey J Cohen; Hyman B Muss; Kenneth E Schmader; Betty Ferrell; Martine Extermann; Susan G Nayfield; Arti Hurria
Journal:  J Natl Cancer Inst       Date:  2012-03-27       Impact factor: 13.506

7.  Accrual of Older Patients With Breast Cancer to Alliance Systemic Therapy Trials Over Time: Protocol A151527.

Authors:  Rachel A Freedman; Jared C Foster; Drew K Seisler; Jacqueline M Lafky; Hyman B Muss; Harvey J Cohen; Jeanne Mandelblatt; Eric P Winer; Clifford A Hudis; Ann H Partridge; Lisa A Carey; Constance Cirrincione; Alvaro Moreno-Aspitia; Gretchen Kimmick; Aminah Jatoi; Arti Hurria
Journal:  J Clin Oncol       Date:  2016-12-19       Impact factor: 44.544

8.  Participation and survival of geriatric patients in Phase I clinical trials: the Karmanos Cancer Institute (KCI) experience.

Authors:  Syed F Zafar; Lance K Heilbrun; Prakash Vishnu; Pallavi Jasti; Raghu Venkatramanamoorthy; Li Ding; Patricia M Lorusso; Elisabeth I Heath
Journal:  J Geriatr Oncol       Date:  2011-01-01       Impact factor: 3.599

9.  Different patterns in the prognostic value of age for bladder cancer-specific survival depending on tumor stages.

Authors:  Huan Feng; Wei Zhang; Jiajun Li; Xiaozhe Lu
Journal:  Am J Cancer Res       Date:  2015-05-15       Impact factor: 6.166

10.  Randomized Trial of a Web-Based Intervention to Address Barriers to Clinical Trials.

Authors:  Neal J Meropol; Yu-Ning Wong; Terrance Albrecht; Sharon Manne; Suzanne M Miller; Anne Lederman Flamm; Al Bowen Benson; Joanne Buzaglo; Michael Collins; Brian Egleston; Linda Fleisher; Michael Katz; Tyler G Kinzy; Tasnuva M Liu; Seunghee Margevicius; Dawn M Miller; David Poole; Nancy Roach; Eric Ross; Mark D Schluchter
Journal:  J Clin Oncol       Date:  2015-12-23       Impact factor: 44.544
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