Literature DB >> 20856700

Ethical and legal implications of cancer genetic testing: do physicians have a duty to warn patients' relatives about possible genetic risks?

Courtney Storm, Rinki Agarwal, Kenneth Offit.   

Abstract

This vignette raises questions about the extent of physicians' obligations to warn relatives of a patient about a hereditary cancer risk.

Entities:  

Year:  2008        PMID： 20856700      PMCID： PMC2794026          DOI： 10.1200/JOP.0858504

Source DB:  PubMed          Journal:  J Oncol Pract        ISSN： 1554-7477            Impact factor:   3.840


  7 in total

1.  Laws restricting health insurers' use of genetic information: impact on genetic discrimination.

Authors:  M A Hall; S S Rich
Journal:  Am J Hum Genet       Date:  2000-01       Impact factor: 11.025

Review 2.  Controversies and ethical issues in cancer-genetics clinics.

Authors:  Marion Harris; Ingrid Winship; Merle Spriggs
Journal:  Lancet Oncol       Date:  2005-05       Impact factor: 41.316

3.  Prohibiting genetic discrimination.

Authors:  Kathy L Hudson
Journal:  N Engl J Med       Date:  2007-05-17       Impact factor: 91.245

4.  ASHG statement. Professional disclosure of familial genetic information. The American Society of Human Genetics Social Issues Subcommittee on Familial Disclosure.

Authors: 
Journal:  Am J Hum Genet       Date:  1998-02       Impact factor: 11.025

5.  Medical Geneticists' duty to warn at-risk relatives for genetic disease.

Authors:  Marni J Falk; R Beth Dugan; Mary Ann O'Riordan; Anne L Matthews; Nathaniel H Robin
Journal:  Am J Med Genet A       Date:  2003-07-30       Impact factor: 2.802

6.  The "duty to warn" a patient's family members about hereditary disease risks.

Authors:  Kenneth Offit; Elizabeth Groeger; Sam Turner; Eve A Wadsworth; Mary A Weiser
Journal:  JAMA       Date:  2004-09-22       Impact factor: 56.272

7.  American Society of Clinical Oncology policy statement update: genetic testing for cancer susceptibility.

Authors: 
Journal:  J Clin Oncol       Date:  2003-04-11       Impact factor: 44.544
  7 in total
  8 in total

1.  Compare and contrast: a cross-national study across UK, USA and Greek experts regarding return of incidental findings from clinical sequencing.

Authors:  Elli G Gourna; Natalie Armstrong; Susan E Wallace
Journal:  Eur J Hum Genet       Date:  2015-06-10       Impact factor: 4.246

2.  Pediatric and Adult Recommendations Vary for Sibling Testing in Cystic Fibrosis.

Authors:  Kimberly L Brown; Patrick A Flume
Journal:  J Genet Couns       Date:  2018-02-10       Impact factor: 2.537

3.  Integrating genomics into clinical oncology: ethical and social challenges from proponents of personalized medicine.

Authors:  Michelle L McGowan; Richard A Settersten; Eric T Juengst; Jennifer R Fishman
Journal:  Urol Oncol       Date:  2014-02       Impact factor: 3.498

Review 4.  Tumor protein p53 (TP53) testing and Li-Fraumeni syndrome : current status of clinical applications and future directions.

Authors:  April D Sorrell; Carin R Espenschied; Julie O Culver; Jeffrey N Weitzel
Journal:  Mol Diagn Ther       Date:  2013-02       Impact factor: 4.074

5.  Germline Mutations in Predisposition Genes in Pediatric Cancer.

Authors:  Jinghui Zhang; Michael F Walsh; Gang Wu; Kim E Nichols; Michael N Edmonson; Tanja A Gruber; John Easton; Dale Hedges; Xiaotu Ma; Xin Zhou; Donald A Yergeau; Mark R Wilkinson; Bhavin Vadodaria; Xiang Chen; Rose B McGee; Stacy Hines-Dowell; Regina Nuccio; Emily Quinn; Sheila A Shurtleff; Michael Rusch; Aman Patel; Jared B Becksfort; Shuoguo Wang; Meaghann S Weaver; Li Ding; Elaine R Mardis; Richard K Wilson; Amar Gajjar; David W Ellison; Alberto S Pappo; Ching-Hon Pui; James R Downing
Journal:  N Engl J Med       Date:  2015-11-18       Impact factor: 91.245

6.  Tumor genome analysis includes germline genome: are we ready for surprises?

Authors:  Daniel V T Catenacci; Andrea L Amico; Sarah M Nielsen; Daniel M Geynisman; Brittany Rambo; George B Carey; Cassandra Gulden; Jim Fackenthal; Robert D Marsh; Hedy L Kindler; Olufunmilayo I Olopade
Journal:  Int J Cancer       Date:  2014-08-14       Impact factor: 7.396

7.  Incidental findings from clinical sequencing in Greece: reporting experts' attitudes.

Authors:  E G Gourna; N Armstrong; S E Wallace
Journal:  J Community Genet       Date:  2014-07-22

Review 8.  Pharmacogenomics cascade testing (PhaCT): a novel approach for preemptive pharmacogenomics testing to optimize medication therapy.

Authors:  Don Roosan; Angela Hwang; Moom R Roosan
Journal:  Pharmacogenomics J       Date:  2020-08-25       Impact factor: 3.550
  8 in total

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