Literature DB >> 20848166

An analysis tool to calculate permeability based on the Patlak method.

Ozdemir Cetin1.   

Abstract

Strokes are commonly diagnosed by utilizing images obtained from magnetic resonance imaging (MRI) technology. Nowadays, computer software can play a large role in analyzing these images and arriving at diagnoses quickly and accurately. Additionally, this software can reduce workload for medical personnel and lower misdiagnoses. In this paper a flexible permeability calculation tool called PCT based on the Patlak plot method is presented. Using the PCT we can calculate the permeability co-efficient of the Blood-Brain Barrier (BBB) function. The PCT tool offers both manual and automatic options for diagnosing the regions of the brain affected by stroke. Moreover, the PCT tool supports various extensions such as dicom, nifty and analyze.

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Year:  2010        PMID: 20848166     DOI: 10.1007/s10916-010-9592-y

Source DB:  PubMed          Journal:  J Med Syst        ISSN: 0148-5598            Impact factor:   4.460


  13 in total

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Journal:  J Cereb Blood Flow Metab       Date:  1985-12       Impact factor: 6.200

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Authors:  C S Patlak; R G Blasberg; J D Fenstermacher
Journal:  J Cereb Blood Flow Metab       Date:  1983-03       Impact factor: 6.200

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7.  Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke.

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Authors:  A Gjedde
Journal:  J Neurochem       Date:  1981-04       Impact factor: 5.372

9.  Post-ischemic leakiness of the blood-brain barrier: a quantitative and systematic assessment by Patlak plots.

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Journal:  Exp Neurol       Date:  2009-06-09       Impact factor: 5.330

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Journal:  Magn Reson Imaging       Date:  2006-11-28       Impact factor: 2.546

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  2 in total

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