Literature DB >> 20846807

Detection of metallo-β-lactamase-encoding genes among clinical isolates of Pseudomonas aeruginosa in northwest of Iran.

Saber Yousefi1, Safar Farajnia, Mohammd Reza Nahaei, Mohammad Taghi Akhi, Reza Ghotaslou, Mohammad Hossein Soroush, Behrooz Naghili, Nima Hosseini Jazani.   

Abstract

The prevalence of metallo-β-lactamase (MBL) production among 104 clinical isolates of Pseudomonas aeruginosa from northwest of Iran was investigated by phenotypic and polymerase chain reaction (PCR) methods. Thirty-nine (37.50%) of isolates were MBL positive by double-disk synergy test. Results of PCR revealed that 18 (17.31%) and 6 (5.77%) imipenem nonsusceptible isolates of P. aeruginosa carried bla(VIM) and bla(IMP) genes respectively, while 92.4% (62/67) of isolates contained class 1 integron gene. This is the first report of MBL-producing P. aeruginosa from northwest of Iran.
Copyright © 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 20846807     DOI: 10.1016/j.diagmicrobio.2010.06.018

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN: 0732-8893            Impact factor:   2.803


  20 in total

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