| Literature DB >> 20843985 |
Yuan Cao1, Jiayao Wu, Qian Liu, Yalin Zhao, Xiaomin Ying, Lei Cha, Ligui Wang, Wuju Li.
Abstract
Bacterial sRNAs are an emerging class of small regulatory RNAs, 40-500 nt in length, which play a variety of important roles in many biological processes through binding to their mRNA or protein targets. A comprehensive database of experimentally confirmed sRNA targets would be helpful in understanding sRNA functions systematically and provide support for developing prediction models. Here we report on such a database--sRNATarBase. The database holds 138 sRNA-target interactions and 252 noninteraction entries, which were manually collected from peer-reviewed papers. The detailed information for each entry, such as supporting experimental protocols, BLAST-based phylogenetic analysis of sRNA-mRNA target interaction in closely related bacteria, predicted secondary structures for both sRNAs and their targets, and available binding regions, is provided as accurately as possible. This database also provides hyperlinks to other databases including GenBank, SWISS-PROT, and MPIDB. The database is available from the web page http://ccb.bmi.ac.cn/srnatarbase/.Mesh：
Substances：
Year: 2010 PMID： 20843985 PMCID： PMC2957045 DOI： 10.1261/rna.2193110
Source DB: PubMed Journal: RNA ISSN： 1355-8382 Impact factor: 4.942