Literature DB >> 20843017

Anti-influenza virus compound from Streptomyces sp. RI18.

Motoki Takagi1, Keiichiro Motohashi, Aya Nagai, Miho Izumikawa, Masahiro Tanaka, Shinichiro Fuse, Takayuki Doi, Keiichiro Iwase, Atsushi Kawaguchi, Kyosuke Nagata, Takashi Takahashi, Kazuo Shin-ya.   

Abstract

Screening for anti-influenza virus activity in compounds isolated from Streptomyces sp. RI18, which was isolated using the membrane filter method, uncovered a novel compound, JBIR-68 (1), which contains a unique skeleton. Its structure was established by extensive NMR and MS analyses. In addition, 1 was synthesized to confirm the configuration of its sugar moiety. Compound 1 inhibited influenza virus growth in plaque assays.

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Year:  2010        PMID： 20843017     DOI： 10.1021/ol102007d

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  5 in total

1.  JBIR-76 and JBIR-77, modified naphthoquinones from Streptomyces sp. RI-77.

Authors:  Keiichiro Motohashi; Miho Izumikawa; Noritaka Kagaya; Motoki Takagi; Kazuo Shin-Ya
Journal:  J Antibiot (Tokyo)       Date:  2016-01-06       Impact factor: 2.649

2.  Selective catalytic hydrogenation of the N-acyl and uridyl double bonds in the tunicamycin family of protein N-glycosylation inhibitors.

Authors:  Neil Pj Price; Michael A Jackson; Karl E Vermillion; Judith A Blackburn; Jiakun Li; Biao Yu
Journal:  J Antibiot (Tokyo)       Date:  2017-11-01       Impact factor: 2.649

3.  Farnesides A and B, sesquiterpenoid nucleoside ethers from a marine-derived Streptomyces sp., strain CNT-372 from Fiji.

Authors:  Ella Zafrir Ilan; Manuel R Torres; Jacques Prudhomme; Karine Le Roch; Paul R Jensen; William Fenical
Journal:  J Nat Prod       Date:  2013-08-29       Impact factor: 4.050

Review 4.  Bacterial terpenome.

Authors:  Jeffrey D Rudolf; Tyler A Alsup; Baofu Xu; Zining Li
Journal:  Nat Prod Rep       Date:  2021-05-26       Impact factor: 15.111

Review 5.  Emerging paradigms of viral diseases and paramount role of natural resources as antiviral agents.

Authors:  R Sagaya Jansi; Ameer Khusro; Paul Agastian; Ahmed Alfarhan; Naif Abdullah Al-Dhabi; Mariadhas Valan Arasu; Rajakrishnan Rajagopal; Damia Barcelo; Amal Al-Tamimi
Journal:  Sci Total Environ       Date:  2020-11-07       Impact factor: 7.963
  5 in total

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