Literature DB >> 20842579

Tick paralysis.

Jonathan A Edlow1.   

Abstract

OPINION STATEMENT: Tick paralysis is a toxin-mediated cause of acute flaccid paralysis. Most practitioners will go through their entire career without ever encountering a case. An important veterinary disease, tick paralysis is rare in humans. Although it has certain geographical proclivities, it exists worldwide. Although it tends to occur in young girls, it can occur in any age group. Due to its rarity, doctors often forget to consider tick paralysis in the differential diagnosis of the weak patient. Therefore it is perhaps not surprising that the literature is full of cases in which a mother stroking her child's head or an alert nurse bathing her patient made the diagnosis serendipitously.Physicians should consider tick paralysis in any patient with an acute flaccid paralysis. As a general rule, aimed more towards patient safety than the likelihood of making a correct diagnosis, never definitively diagnose Guillain-Barré syndrome without first searching the entire body for a tick. The treatment of tick paralysis is among the simplest and most gratifying in all of medicine. Tick removal results in rapid improvement of all symptoms. Some patients may require mechanical ventilation and support in an intensive care unit as the toxin clears. Since tick paralysis is toxin-mediated and not caused by an infectious agent, antimicrobials are not indicated. Finally, prevention of tick paralysis, as with most tick-borne diseases, involves changing behavior to avoid tick exposure and performing frequent tick checks to remove them if they have already attached.

Entities:  

Year:  2010        PMID: 20842579     DOI: 10.1007/s11940-010-0068-7

Source DB:  PubMed          Journal:  Curr Treat Options Neurol        ISSN: 1092-8480            Impact factor:   3.598


  46 in total

1.  A six-year-old girl with tick paralysis.

Authors:  M W Felz; C D Smith; T R Swift
Journal:  N Engl J Med       Date:  2000-01-13       Impact factor: 91.245

2.  Site and mechanism of tick paralysis.

Authors:  M F MURNAGHAN
Journal:  Science       Date:  1960-02-12       Impact factor: 47.728

3.  TICK PARALYSIS IN BRITISH COLUMBIA.

Authors:  G A Mail; J D Gregson
Journal:  Can Med Assoc J       Date:  1938-12       Impact factor: 8.262

4.  Leg weakness associated with Powassan virus infection--Ontario.

Authors:  A C Jackson
Journal:  Can Dis Wkly Rep       Date:  1989-06-17

5.  Isolation of tick paralysis toxin from Ixodes holocyclus.

Authors:  G H Kaire
Journal:  Toxicon       Date:  1966-08       Impact factor: 3.033

Review 6.  Does this patient have myasthenia gravis?

Authors:  Katalin Scherer; Richard S Bedlack; David L Simel
Journal:  JAMA       Date:  2005-04-20       Impact factor: 56.272

Review 7.  Biochemical perspectives on paralysis and other forms of toxicoses caused by ticks.

Authors:  B J Mans; R Gothe; A W H Neitz
Journal:  Parasitology       Date:  2004       Impact factor: 3.234

Review 8.  Proposed diagnostic criteria and nosology of acute transverse myelitis.

Authors: 
Journal:  Neurology       Date:  2002-08-27       Impact factor: 9.910

9.  Acute transverse myelitis in children: clinical course and prognostic factors.

Authors:  Pierre Defresne; Henri Hollenberg; Béatrice Husson; Brahim Tabarki; Pierre Landrieu; Gilbert Huault; Marc Tardieu; Guillaume Sébire
Journal:  J Child Neurol       Date:  2003-06       Impact factor: 1.987

10.  Tetrodotoxin poisoning.

Authors:  Chorng-Kuang How; Chii-Hwa Chern; Yin-Chieh Huang; Lee-Min Wang; Chen-Hsen Lee
Journal:  Am J Emerg Med       Date:  2003-01       Impact factor: 2.469

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  5 in total

1.  Avoiding misdiagnosis in patients with neurological emergencies.

Authors:  Jennifer V Pope; Jonathan A Edlow
Journal:  Emerg Med Int       Date:  2012-07-25       Impact factor: 1.112

Review 2.  Venomous and poisonous Australian animals of veterinary importance: a rich source of novel therapeutics.

Authors:  Margaret C Hardy; Jonathon Cochrane; Rachel E Allavena
Journal:  Biomed Res Int       Date:  2014-07-21       Impact factor: 3.411

3.  Use of big data in the surveillance of veterinary diseases: early detection of tick paralysis in companion animals.

Authors:  Vanina Guernier; Gabriel J Milinovich; Marcos Antonio Bezerra Santos; Mark Haworth; Glen Coleman; Ricardo J Soares Magalhaes
Journal:  Parasit Vectors       Date:  2016-05-23       Impact factor: 3.876

4.  An Immunosuppressant Peptide from the Hard Tick Amblyomma variegatum.

Authors:  Yufeng Tian; Wenlin Chen; Guoxiang Mo; Ran Chen; Mingqian Fang; Gabriel Yedid; Xiuwen Yan
Journal:  Toxins (Basel)       Date:  2016-05-03       Impact factor: 4.546

5.  A Case of Tick-Borne Paralysis in a Traveling Patient.

Authors:  Kevin Ha; Kathryn Lewis; Vandan Patel; Jennifer Grinceri
Journal:  Case Rep Neurol Med       Date:  2019-06-27
  5 in total

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